Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   SCI_RS07515 Genome accession   NC_022238
Coordinates   1521863..1524142 (+) Length   759 a.a.
NCBI ID   WP_020999401.1    Uniprot ID   -
Organism   Streptococcus constellatus subsp. pharyngis C1050     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1516863..1529142
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCI_RS07495 (SCI_1467) - 1517849..1518391 (-) 543 WP_020997988.1 ClbS/DfsB family four-helix bundle protein -
  SCI_RS10330 (SCI_1468) - 1518465..1518599 (-) 135 WP_003031275.1 FeoB-associated Cys-rich membrane protein -
  SCI_RS07500 (SCI_1469) feoB 1518608..1520753 (-) 2146 Protein_1492 ferrous iron transport protein B -
  SCI_RS07505 (SCI_1470) - 1520750..1521226 (-) 477 WP_003068195.1 FeoA family protein -
  SCI_RS07510 (SCI_1471) - 1521394..1521624 (-) 231 WP_006267994.1 DUF1797 family protein -
  SCI_RS07515 (SCI_1473) clpE 1521863..1524142 (+) 2280 WP_020999401.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  SCI_RS07520 (SCI_1474) - 1524189..1524794 (-) 606 WP_006268194.1 GyrI-like domain-containing protein -
  SCI_RS07525 (SCI_1475) - 1524922..1525575 (-) 654 WP_006268402.1 YafY family protein -
  SCI_RS10950 - 1525541..1525744 (-) 204 WP_003068185.1 YafY family protein -
  SCI_RS07535 (SCI_1476) - 1525901..1526350 (+) 450 Protein_1499 NUDIX hydrolase -
  SCI_RS07540 (SCI_1477) - 1526415..1526714 (+) 300 WP_006268083.1 DUF1827 family protein -
  SCI_RS07545 (SCI_1478) - 1527068..1527706 (-) 639 WP_321163008.1 IS982 family transposase -
  SCI_RS07550 (SCI_1479) - 1527936..1528481 (-) 546 WP_006268095.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 759 a.a.        Molecular weight: 84797.01 Da        Isoelectric Point: 5.0266

>NTDB_id=61605 SCI_RS07515 WP_020999401.1 1521863..1524142(+) (clpE) [Streptococcus constellatus subsp. pharyngis C1050]
MLCQNCKINESTIHLYTNVNGKQHQVDLCQNCYQIMKTDPNNALFRGMTNMNNQNNLDPFDDFFSNLGNFQNHQEPQTPP
TQSGGGYGNGGYGSNQGGSTRQQVPQQPKGLLEEFGINVTEFARRGEIDPVIGRDEEIVRVIEILNRRTKNNPVLIGEPG
VGKTAVVEGLAQKIVDGDVPHKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMNEIRSRQDVILFIDEIHEIVGAGSAG
DGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVKYTDDAI
EAAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKIIDQRLVEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQ
QNKMADQDTPLISEKTIEHIIEQKTNIPVGDLKEKEQSQLISLADDLKAHVIGQDDAVDKIAKAIRRNRVGLGTPDRPIG
SFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYEEAGQLTERVRRNPYSLILLDEI
EKAHLDVMHMFLQVLDDGRLTDGQGRTVNFKDTIIIMTSNAGTGKVEANVGFGAAREGRTNSVLSELGNFFSPEFINRFD
GIIEFKSLSKENLLQIVDLMLEDVNKRLAVNGIHLDVTDKVKEKLVNLGYDPKMGARPLRRTIQDHIEDAITDYYLEHPS
EKELKAVMTSNSKIVIKSSKKSENETEKEIKTTADDTAN

Nucleotide


Download         Length: 2280 bp        

>NTDB_id=61605 SCI_RS07515 WP_020999401.1 1521863..1524142(+) (clpE) [Streptococcus constellatus subsp. pharyngis C1050]
ATGCTTTGTCAAAATTGTAAAATAAACGAATCAACTATTCACCTTTACACAAATGTGAATGGAAAACAACACCAAGTTGA
CCTCTGTCAAAATTGTTATCAAATCATGAAAACAGACCCAAATAATGCCTTATTTCGTGGCATGACCAATATGAACAATC
AAAATAATTTAGACCCTTTTGATGATTTCTTTAGCAATCTAGGGAATTTTCAAAATCATCAAGAACCGCAGACCCCTCCT
ACTCAATCAGGTGGCGGATACGGTAACGGAGGCTATGGTTCCAATCAAGGTGGCAGCACGCGCCAACAAGTACCACAACA
ACCCAAAGGCCTCCTAGAAGAATTTGGTATCAATGTAACTGAATTTGCTCGGCGGGGCGAGATTGACCCTGTAATTGGTC
GTGACGAAGAAATTGTGCGCGTCATTGAAATCCTCAATCGTAGAACGAAGAACAATCCTGTCCTCATCGGAGAGCCCGGT
GTCGGTAAAACAGCAGTTGTCGAAGGCTTGGCTCAGAAAATTGTAGACGGTGATGTGCCACATAAACTCCAAGGCAAAGA
AGTCATTCGTTTAGATGTCGTTAGTTTGGTTCAAGGAACTGGTATCCGTGGTCAATTTGAAGAACGAATGCAAAAACTCA
TGAACGAAATTCGCTCTCGACAAGATGTTATATTATTCATTGATGAAATTCACGAAATTGTTGGAGCTGGTTCTGCTGGC
GATGGAAATATGGATGCTGGAAACATCCTAAAACCAGCACTTGCTCGCGGTGAACTCCAATTAGTCGGTGCCACAACTCT
CAATGAATACCGGATTATCGAAAAAGATGCTGCACTGGAACGCCGTATGCAGCCTGTAAAAGTTGATGAACCAACAGTTG
AAGAAACGATCACTATCCTCAAAGGTATTCAAAAGAAATACGAAGACTATCACCACGTCAAATACACAGACGATGCCATT
GAAGCAGCAGCTGTCTTGTCCAATCGTTATATCCAAGATCGCTTCTTGCCTGATAAGGCCATTGACTTGCTAGACGAAGC
AGGCTCTAAGATGAATCTGACACTTAACTTTGTCGATCCAAAAATCATTGATCAACGATTGGTAGAAGCTGAAAACCTCA
AGGCACAAGCTACTCGTGATGAAGATTTTGAAAAAGCTGCTTATTTCCGTGACCAAATTGCCAAATACAAAGAAATGCAG
CAAAATAAAATGGCTGATCAAGATACGCCTCTTATCAGTGAAAAAACCATTGAACATATCATTGAGCAAAAGACAAATAT
TCCAGTTGGCGACTTGAAAGAAAAGGAACAATCACAATTGATTAGTCTGGCTGATGATTTGAAAGCTCATGTCATTGGTC
AAGATGATGCTGTTGATAAAATTGCGAAGGCCATTCGCCGTAATCGAGTTGGACTAGGTACACCAGACCGACCAATTGGT
TCTTTCCTTTTTGTTGGACCAACCGGTGTCGGCAAAACAGAACTTTCTAAACAACTAGCGATTGAGCTCTTTGGTTCAGC
TGACAGCATGATTCGTTTTGATATGAGTGAGTATATGGAAAAACATAGCGTAGCAAAACTCGTCGGAGCGCCTCCAGGTT
ACGTTGGCTACGAAGAAGCTGGACAATTAACAGAACGTGTACGTCGTAATCCTTATTCTCTCATTTTACTTGATGAAATA
GAAAAAGCTCACCTAGATGTCATGCATATGTTCTTGCAAGTACTTGATGACGGACGTCTGACAGATGGACAAGGTCGGAC
AGTCAATTTCAAAGATACGATTATCATTATGACTTCCAACGCCGGTACTGGAAAAGTCGAAGCAAACGTTGGATTTGGTG
CAGCGCGTGAAGGACGAACCAATTCCGTCCTCAGTGAATTGGGCAACTTCTTCAGCCCAGAATTTATAAATCGTTTCGAT
GGTATTATTGAGTTCAAATCTCTTAGCAAGGAAAATCTCCTACAAATCGTAGATTTGATGCTTGAAGATGTGAATAAACG
CTTAGCTGTAAATGGTATTCACCTAGACGTAACAGACAAAGTCAAGGAAAAATTAGTTAATCTTGGTTACGATCCAAAAA
TGGGAGCTCGTCCACTTCGTCGGACAATCCAAGATCACATCGAGGATGCTATCACCGACTACTATCTTGAACATCCAAGC
GAAAAAGAGCTCAAAGCTGTCATGACGAGCAATAGCAAGATTGTTATCAAGTCGTCCAAAAAGTCTGAAAACGAGACCGA
AAAAGAAATTAAAACAACAGCAGACGACACTGCTAACTGA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(648-722)

AAA domain (Cdc48 subfamily) (AAA_2)

(477-640)

AAA lid domain (AAA_lid_9)

(292-389)

ATPase family associated with various cellular activities (AAA) (AAA)

(154-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

86.436

99.078

0.856
  clpE Streptococcus pneumoniae D39

86.436

99.078

0.856
  clpE Streptococcus pneumoniae R6

86.436

99.078

0.856
  clpE Streptococcus pneumoniae TIGR4

86.436

99.078

0.856
  clpE Streptococcus mutans UA159

84.058

100

0.841
  clpC Lactococcus lactis subsp. cremoris KW2

75.826

99.736

0.756
  clpC Bacillus subtilis subsp. subtilis str. 168

49.857

91.963

0.459
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.393

85.903

0.407
  clpC Streptococcus pneumoniae Rx1

48.392

81.95

0.397
  clpC Streptococcus pneumoniae D39

48.392

81.95

0.397
  clpC Streptococcus pneumoniae TIGR4

48.232

81.95

0.395
  clpC Streptococcus mutans UA159

47.276

82.213

0.389
  clpC Streptococcus thermophilus LMD-9

47.191

82.082

0.387
  clpC Streptococcus thermophilus LMG 18311

47.115

82.213

0.387

Multiple sequence alignment