Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   EKM74_RS02135 Genome accession   NZ_AP019306
Coordinates   414654..415928 (+) Length   424 a.a.
NCBI ID   WP_001279338.1    Uniprot ID   A0A0H2XGV4
Organism   Staphylococcus aureus strain TUM9463     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 409654..420928
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EKM74_RS02115 - 410979..411074 (+) 96 WP_031761395.1 hypothetical protein -
  EKM74_RS02120 - 411035..412165 (-) 1131 WP_000721699.1 HAD family hydrolase -
  EKM74_RS02125 nagE 412271..413737 (-) 1467 WP_042109272.1 N-acetylglucosamine-specific PTS transporter subunit IIBC -
  EKM74_RS02130 - 413865..414482 (-) 618 WP_000287588.1 lysophospholipid acyltransferase family protein -
  EKM74_RS02135 htrA 414654..415928 (+) 1275 WP_001279338.1 S1C family serine protease Regulator
  EKM74_RS02140 tyrS 416022..417284 (-) 1263 WP_000186029.1 tyrosine--tRNA ligase -
  EKM74_RS02145 - 417666..418571 (+) 906 WP_000184370.1 transglycosylase domain-containing protein -
  EKM74_RS02150 - 418551..418643 (-) 93 WP_031761401.1 hypothetical protein -

Sequence

Protein


Download         Length: 424 a.a.        Molecular weight: 45802.98 Da        Isoelectric Point: 9.9696

>NTDB_id=61603 EKM74_RS02135 WP_001279338.1 414654..415928(+) (htrA) [Staphylococcus aureus strain TUM9463]
MSDFNHTDHSTTNHSQTPRYRRPKFPWFKTVIVALIAGIIGALLVLGIGKVLNSTILNKDGSTVQTTNNKGGNQLDGQSK
KFGTVHEMIKSVSPTIVGVINMQKASSVDDLLKGKSSKPSEAGVGSGVIYQINNNSAYIVTNNHVIDGANEIRVQLHNKK
QVKAKLVGKDAVTDIAVLKIENTKGIKAIQFANSSKVQTGDSVFAMGNPLGLQFANSVTSGIISASERTIDAETTGGNTK
VSVLQTDAAINPGNSGGALVDINGNLVGINSMKIAATQVEGIGFAIPSNEVKVTIEQLVKHGKIDRPSIGIGLINLKDIP
EEEREQLHTDREDGIYVAKADSDIDLKKGDIITEIDGKKIKDDVDLRSYLYENKKPGESVTVTVIRDGKTKEVKVKLKQQ
KEQPKRQSRSERQSPGQGDRDFFR

Nucleotide


Download         Length: 1275 bp        

>NTDB_id=61603 EKM74_RS02135 WP_001279338.1 414654..415928(+) (htrA) [Staphylococcus aureus strain TUM9463]
ATGTCAGATTTTAATCATACAGATCATTCTACAACAAACCATAGCCAAACACCTAGATACAGAAGACCTAAATTTCCATG
GTTTAAAACAGTCATCGTTGCATTGATTGCTGGAATTATTGGTGCACTTCTAGTACTTGGTATAGGCAAAGTATTAAATA
GTACAATTTTAAATAAAGATGGTTCAACTGTTCAGACAACAAATAATAAAGGTGGCAATCAATTAGACGGTCAAAGCAAG
AAATTCGGTACCGTTCATGAAATGATAAAATCTGTCTCCCCTACAATTGTTGGAGTTATTAACATGCAAAAAGCATCAAG
TGTAGACGACTTATTAAAAGGCAAATCATCTAAACCATCTGAAGCTGGAGTAGGTTCAGGTGTTATCTATCAAATAAACA
ACAATTCAGCTTATATCGTTACAAACAATCATGTTATTGATGGCGCAAATGAAATTAGAGTCCAATTACATAATAAAAAA
CAAGTTAAAGCGAAATTAGTTGGTAAAGATGCAGTAACTGATATTGCTGTACTTAAAATTGAAAATACAAAAGGTATTAA
AGCGATTCAATTTGCCAACTCTTCAAAAGTACAAACTGGCGATAGCGTATTCGCAATGGGTAACCCATTAGGATTACAAT
TTGCTAACTCTGTAACATCTGGTATCATTTCAGCAAGCGAACGTACGATTGACGCTGAGACAACTGGTGGCAATACAAAA
GTTAGCGTTCTTCAAACAGATGCTGCTATTAACCCAGGTAACTCAGGTGGCGCATTAGTAGATATTAATGGTAATTTAGT
TGGTATTAACTCAATGAAAATTGCTGCGACACAAGTTGAAGGTATCGGGTTTGCTATTCCAAGTAATGAAGTTAAAGTAA
CAATTGAACAACTTGTAAAACATGGTAAAATTGACCGCCCTTCGATTGGTATTGGTTTAATTAATTTGAAAGATATTCCT
GAAGAAGAGCGCGAGCAACTTCATACTGATAGAGAAGACGGTATTTATGTCGCCAAAGCTGATAGTGATATTGATCTTAA
AAAAGGTGATATTATTACAGAAATTGATGGCAAGAAAATTAAAGATGATGTTGATTTAAGAAGCTATTTATATGAAAATA
AAAAACCTGGTGAATCAGTCACTGTTACCGTTATCCGTGATGGTAAAACAAAAGAAGTTAAAGTGAAATTAAAACAACAA
AAAGAACAACCAAAACGTCAAAGCCGATCAGAACGTCAATCACCTGGCCAAGGCGATAGAGATTTCTTTAGATAA

Domains

Predicted by InterProScan.

Trypsin-like peptidase domain (Trypsin_2)

(125-269)

PDZ domain (PDZ_2)

(307-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XGV4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

39.055

94.811

0.37

Multiple sequence alignment