Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE2   Type   Regulator
Locus tag   NQZ93_RS05185 Genome accession   NZ_CP102141
Coordinates   1068771..1069520 (-) Length   249 a.a.
NCBI ID   WP_024381039.1    Uniprot ID   -
Organism   Streptococcus suis strain DNR48     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1063771..1074520
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ93_RS05180 (NQZ93_05180) - 1067549..1068184 (-) 636 WP_024381040.1 hypothetical protein -
  NQZ93_RS05185 (NQZ93_05185) comE/comE2 1068771..1069520 (-) 750 WP_024381039.1 LytTR family transcriptional regulator DNA-binding domain-containing protein Regulator
  NQZ93_RS05190 (NQZ93_05190) - 1069535..1070404 (-) 870 WP_228380944.1 GHKL domain-containing protein -
  NQZ93_RS05195 (NQZ93_05195) - 1070864..1071019 (-) 156 WP_024381037.1 hypothetical protein -
  NQZ93_RS05200 (NQZ93_05200) comA 1071041..1073191 (-) 2151 WP_024390738.1 peptide cleavage/export ABC transporter Regulator
  NQZ93_RS05205 (NQZ93_05205) - 1073395..1073586 (-) 192 WP_024381035.1 hypothetical protein -
  NQZ93_RS05210 (NQZ93_05210) - 1073675..1073947 (-) 273 WP_024381592.1 DUF3884 family protein -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29330.83 Da        Isoelectric Point: 7.3690

>NTDB_id=615288 NQZ93_RS05185 WP_024381039.1 1068771..1069520(-) (comE/comE2) [Streptococcus suis strain DNR48]
MNIIVLDDNIHHQLRLESALYDVARSLHIHINIECARTIQALREYMNQEEVNQIYFLDLEIGNQKNLGFEIAKEIRNNNP
YAVIIFVTSYSDLMPLVFQYHLSALDFIIKDLKETEFRNRLKQCLEQVIISFKKKSDGELLRYSYQNRTGICIPFSDILF
IQTSVKPHRLIIYTVDFIKEFYGTLNDILDLDSKNYFEKVDRSTIINVDNVTEYSSKTREVKFFEGTTCLVSRLRIKDVK
TRLRNKGII

Nucleotide


Download         Length: 750 bp        

>NTDB_id=615288 NQZ93_RS05185 WP_024381039.1 1068771..1069520(-) (comE/comE2) [Streptococcus suis strain DNR48]
ATGAATATTATTGTTCTGGATGACAATATTCATCATCAGTTGCGACTAGAATCTGCTCTTTATGATGTAGCTCGGTCTTT
ACATATTCATATCAATATTGAATGTGCTAGAACAATACAGGCATTAAGAGAGTATATGAATCAAGAAGAAGTAAATCAGA
TATATTTTCTAGATTTAGAAATTGGCAACCAAAAAAATTTAGGTTTTGAGATTGCTAAAGAAATAAGAAATAATAATCCT
TATGCAGTTATTATATTTGTGACTTCATATTCCGACTTGATGCCCCTAGTATTTCAATATCATCTTTCGGCATTAGATTT
TATTATTAAAGATCTTAAAGAAACAGAATTTCGTAATCGGTTAAAGCAGTGTTTGGAACAAGTAATAATTTCATTTAAGA
AAAAATCTGATGGGGAATTGTTAAGATATAGTTACCAGAACAGAACTGGTATCTGCATACCTTTTTCCGATATACTTTTT
ATTCAAACCTCAGTTAAACCGCATCGATTAATTATTTATACAGTAGATTTTATTAAAGAATTTTATGGTACTTTGAATGA
TATTCTAGATTTAGATAGTAAGAATTATTTTGAAAAAGTAGATCGTTCAACAATAATAAATGTGGATAATGTTACTGAGT
ACAGTTCGAAAACAAGAGAAGTAAAATTTTTTGAAGGAACAACATGTCTTGTATCTAGATTGAGAATTAAGGATGTAAAA
ACTAGATTAAGAAATAAAGGAATAATATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(152-243)

Response regulator receiver domain (Response_reg)

(4-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

37.751

100

0.378
  comE/comE2 Streptococcus gordonii strain NCTC7865

37.751

100

0.378
  comE Streptococcus mitis SK321

36.614

100

0.373
  comE Streptococcus pneumoniae Rx1

36.614

100

0.373
  comE Streptococcus mitis NCTC 12261

36.614

100

0.373
  comE Streptococcus pneumoniae R6

36.614

100

0.373
  comE Streptococcus pneumoniae TIGR4

36.614

100

0.373
  comE Streptococcus pneumoniae D39

36.614

100

0.373
  comE Streptococcus infantis strain Atu-4

36.546

100

0.365
  comE/blpR Streptococcus mutans UA159

36.145

100

0.361