Detailed information NTG0615155

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: LIO34_RS00820
• Genome accession: NZ_CP085085
• Coordinates: 127952..128905 (+)
• Length: 317 a.a.
• NCBI ID: WP_024409299.1
• Uniprot ID: A0A7Y6VE95
• Organism: Streptococcus suis strain Ssuis_MA8
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 122952..133905

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LIO34_RS00780	-	123215..124165 (-)	951	WP_002936565.1	S66 peptidase family protein	-
LIO34_RS00785	comYA	124251..125201 (+)	951	WP_002936562.1	competence type IV pilus ATPase ComGA	Machinery gene
LIO34_RS00790	comYB	125113..126150 (+)	1038	WP_255195823.1	competence type IV pilus assembly protein ComGB	Machinery gene
LIO34_RS00795	comYC	126152..126433 (+)	282	WP_009909092.1	competence type IV pilus major pilin ComGC	Machinery gene
LIO34_RS00800	comGD	126414..126821 (+)	408	WP_009909093.1	competence type IV pilus minor pilin ComGD	-
LIO34_RS00805	comYE	126793..127086 (+)	294	WP_024390433.1	competence type IV pilus minor pilin ComGE	Machinery gene
LIO34_RS00810	comGF/cglF	127073..127507 (+)	435	WP_009909097.1	competence type IV pilus minor pilin ComGF	Machinery gene
LIO34_RS00815	comGG	127485..127895 (+)	411	WP_009909099.1	competence type IV pilus minor pilin ComGG	-
LIO34_RS00820	comYH	127952..128905 (+)	954	WP_024409299.1	class I SAM-dependent methyltransferase	Machinery gene
LIO34_RS00825	-	128955..130142 (+)	1188	WP_013730078.1	acetate kinase	-
LIO34_RS00830	-	130457..131053 (+)	597	WP_009909104.1	folate family ECF transporter S component	-
LIO34_RS00835	-	131064..132320 (+)	1257	WP_013730079.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-
LIO34_RS00840	pepA	132366..133427 (-)	1062	WP_002936538.1	glutamyl aminopeptidase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 35807.97 Da
• Isoelectric Point: 4.4571

>NTDB_id=615155 LIO34_RS00820 WP_024409299.1 127952..128905(+) (comYH) [Streptococcus suis strain Ssuis_MA8]
MNFEKIEQAYDLLLENVQTIQNQLGTNIYDAMIEQNAAYVANQHEMDLVVNNNKTLKQLDLTKEEWRRAYQFLLIKANQT
EPMQYNHQFTPDSIGFILSFLVDQLMPTQKVTVLEIGSGTGNLAQTILNASQKELDYLGIEVDDLLIDLSASIADVMQAD
ISFAQGDAVRPQILKESQVILGDLPIGYYPDDQIASRYQVASPNEHTYAHHLLMEQSLKYLEKDGFAILLAPNDLLTSPQ
SDLLKGWLQEQANIVAMIALPPNLFGKAAMAKSIFVLQKKAARSLTPFVYPLQSLQEPEAIQKFMLNFKNWKQENAI

Nucleotide

• Length: 954 bp

>NTDB_id=615155 LIO34_RS00820 WP_024409299.1 127952..128905(+) (comYH) [Streptococcus suis strain Ssuis_MA8]
ATGAATTTTGAAAAGATCGAACAGGCTTACGACCTGCTATTAGAAAACGTACAGACTATCCAAAACCAGCTAGGTACCAA
TATCTATGATGCCATGATTGAGCAAAATGCTGCTTACGTAGCTAATCAGCATGAGATGGACCTTGTTGTCAATAATAACA
AGACCTTGAAACAACTAGATTTAACCAAGGAAGAATGGCGTCGTGCCTATCAATTCTTGCTCATCAAGGCCAATCAGACT
GAACCCATGCAGTACAATCACCAGTTCACACCAGACTCTATCGGATTTATCCTATCTTTTCTAGTAGACCAATTGATGCC
GACTCAAAAGGTGACGGTTCTGGAAATTGGTTCGGGGACAGGCAATCTAGCTCAGACCATTCTCAACGCCAGCCAGAAAG
AATTGGATTACTTGGGGATCGAAGTGGACGACCTCTTGATTGATTTGTCGGCAAGTATTGCGGATGTCATGCAGGCAGAT
ATTTCTTTTGCTCAGGGAGATGCGGTACGTCCGCAGATTTTGAAGGAAAGTCAAGTAATTTTGGGAGATTTGCCTATTGG
CTACTATCCAGATGACCAGATTGCTAGCCGCTATCAGGTCGCCAGCCCAAATGAACATACCTACGCCCATCATTTACTCA
TGGAACAATCCCTGAAATATCTGGAAAAAGATGGCTTTGCGATTTTGTTGGCTCCAAATGATTTATTGACTAGTCCGCAA
AGCGATTTGCTGAAAGGTTGGTTACAGGAGCAAGCCAATATTGTTGCCATGATTGCCCTGCCACCAAATCTCTTTGGGAA
GGCTGCTATGGCCAAGTCTATTTTTGTCTTGCAAAAGAAAGCTGCAAGATCGTTGACGCCGTTTGTTTATCCCTTACAAA
GTCTTCAAGAACCAGAAGCTATTCAGAAGTTCATGCTCAATTTCAAAAATTGGAAGCAAGAGAATGCAATTTAA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (68-283)

3D structure

• AlphaFold DB: A0A7Y6VE95

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA140	60.759	99.685	0.606
comYH	Streptococcus mutans UA159	60.443	99.685	0.603