Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   SII_RS01950 Genome accession   NC_022237
Coordinates   373581..375848 (-) Length   755 a.a.
NCBI ID   WP_020998370.1    Uniprot ID   -
Organism   Streptococcus intermedius C270     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 368581..380848
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SII_RS01920 (SII_0378) - 368612..368866 (+) 255 WP_003071936.1 hypothetical protein -
  SII_RS01925 (SII_0379) - 368878..370932 (+) 2055 WP_020998368.1 cation:proton antiporter -
  SII_RS01930 (SII_0380) - 371007..371306 (-) 300 WP_003071940.1 DUF1827 family protein -
  SII_RS01935 (SII_0381) - 371370..371819 (-) 450 WP_009569172.1 NUDIX hydrolase -
  SII_RS01940 (SII_0382) - 371976..372869 (+) 894 WP_009569171.1 helix-turn-helix transcriptional regulator -
  SII_RS01945 (SII_0383) - 372929..373534 (+) 606 WP_020998369.1 GyrI-like domain-containing protein -
  SII_RS01950 (SII_0384) clpE 373581..375848 (-) 2268 WP_020998370.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  SII_RS01955 (SII_0385) - 376088..376318 (+) 231 WP_003023686.1 DUF1797 family protein -
  SII_RS01960 (SII_0386) - 376487..376963 (+) 477 WP_020998371.1 FeoA family protein -
  SII_RS01965 (SII_0387) feoB 376960..379092 (+) 2133 WP_020998372.1 ferrous iron transport protein B -
  SII_RS09615 (SII_0388) - 379101..379238 (+) 138 WP_003071957.1 FeoB-associated Cys-rich membrane protein -
  SII_RS01970 (SII_0389) - 379370..379912 (+) 543 WP_003077029.1 ClbS/DfsB family four-helix bundle protein -

Sequence

Protein


Download         Length: 755 a.a.        Molecular weight: 84305.54 Da        Isoelectric Point: 5.2134

>NTDB_id=61512 SII_RS01950 WP_020998370.1 373581..375848(-) (clpE) [Streptococcus intermedius C270]
MLCQNCKINESTIHLYTNVNGKQHQVDLCQNCYQIMKTDPNNALFRGMTNMNNQNNLDPFDDFFSNIGNFQNHQEPQTPP
TQSGGGYGNGGYGSNQGNSTRQQASQQPKGLLEEFGINVTEFARRGEIDPVIGRDEEIVRVIEILNRRTKNNPVLIGEPG
VGKTAVVEGLAQKIVDGDVPHKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMNEIRSRQDVILFIDEIHEIVGAGSAG
DGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVKYTDDAI
EAAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLVEAGNLKAQATRDEDFEKAAYFRDQIAKYKEMQ
QNKMADQDTPLISEKTIEHIIEQKTNIPVGDLKEKEQSQLISLADDLKTHVIGQDDAVDKIAKAIRRNRVGLGTPNRPIG
SFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYEEAGQLTERVRRNPYSLILLDEI
EKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGRTNSVIGELGNFFSPEFMNRFD
GIIEFKSLSKENLLQIVDLMLKDVNERLATNDIYLDVTDKVKEKLVNLGYDPKMGARPLRRTIQDHIEDAITDYYLEHPS
DKELKAIMISNGKIVIKPAKKSENKSKTTIDNNAN

Nucleotide


Download         Length: 2268 bp        

>NTDB_id=61512 SII_RS01950 WP_020998370.1 373581..375848(-) (clpE) [Streptococcus intermedius C270]
ATGCTTTGTCAAAACTGTAAAATAAATGAATCTACCATTCATCTTTACACAAATGTTAATGGGAAACAACATCAAGTTGA
CCTCTGTCAAAATTGTTATCAAATCATGAAAACGGATCCAAATAATGCCTTATTTCGTGGCATGACCAATATGAATAATC
AAAACAACCTAGACCCATTTGATGATTTCTTTAGCAATATAGGGAATTTTCAAAATCATCAAGAACCGCAGACTCCTCCT
ACTCAATCAGGTGGTGGATATGGCAATGGAGGCTATGGCTCCAATCAAGGCAATAGTACACGCCAACAAGCATCACAGCA
ACCTAAAGGTCTCCTAGAGGAATTCGGTATCAATGTGACTGAATTTGCTCGGCGTGGTGAAATTGACCCCGTGATTGGTC
GTGATGAGGAAATTGTTCGTGTTATTGAAATCCTTAATCGTAGAACGAAGAACAACCCTGTCCTCATCGGAGAGCCCGGT
GTCGGGAAAACAGCAGTTGTCGAAGGCTTAGCTCAGAAAATTGTAGACGGTGATGTGCCACATAAACTCCAAGGCAAAGA
AGTTATCCGCTTAGATGTCGTTAGCTTGGTTCAAGGAACTGGTATCCGTGGTCAATTTGAAGAACGAATGCAAAAACTCA
TGAACGAAATTCGCTCTCGTCAGGATGTGATATTATTCATTGATGAAATTCACGAAATTGTTGGAGCTGGTTCTGCCGGT
GATGGAAATATGGATGCTGGAAACATTCTAAAACCAGCACTTGCTCGCGGTGAACTCCAATTAGTTGGTGCCACAACTCT
CAATGAATACCGGATTATCGAAAAAGATGCTGCACTGGAACGCCGTATGCAGCCTGTAAAAGTTGATGAACCAACAGTTG
AAGAAACGATCACTATCCTCAAAGGTATTCAAAAGAAATACGAAGACTATCACCACGTCAAATACACCGACGATGCCATT
GAAGCAGCAGCTGTCTTGTCCAATCGGTATATCCAAGATCGCTTCTTGCCTGATAAGGCCATTGACTTGCTAGATGAAGC
AGGCTCTAAGATGAATCTGACACTTAACTTTGTCGATCCAAAAGTCATTGATCAACGATTGGTAGAAGCTGGAAATCTCA
AGGCACAAGCTACTCGTGATGAAGATTTTGAAAAAGCTGCTTATTTCCGTGACCAAATTGCCAAATACAAAGAAATGCAG
CAAAATAAAATGGCTGATCAAGATACGCCTCTTATCAGTGAAAAAACCATTGAACATATCATTGAGCAAAAGACCAATAT
TCCAGTTGGCGACTTGAAAGAAAAGGAACAATCACAATTGATTAGTCTGGCTGATGATTTGAAAACTCATGTCATTGGTC
AAGATGATGCTGTTGATAAAATTGCCAAAGCTATTCGCCGTAATCGAGTTGGACTAGGTACACCAAACCGACCAATTGGT
TCTTTCCTTTTTGTTGGGCCAACCGGTGTCGGCAAAACAGAACTTTCTAAACAACTAGCGATTGAGCTCTTTGGTTCAGC
TGACAGCATGATTCGCTTTGATATGAGTGAGTATATGGAAAAACATAGCGTAGCAAAACTCGTCGGAGCGCCTCCAGGTT
ATGTTGGCTACGAAGAGGCTGGGCAATTAACAGAACGCGTACGTCGTAATCCTTATTCTCTCATTTTACTTGATGAAATA
GAAAAAGCTCACCCAGATGTCATGCACATGTTCTTGCAAGTACTGGATGACGGACGTCTGACAGATGGACAAGGTCGGAC
AGTCAGTTTCAAAGATACGATTATCATTATGACTTCCAACGCCGGTACTGGAAAAGTTGAAGCAAACGTTGGATTTGGTG
CAGCGCGTGAAGGACGAACTAATTCTGTTATCGGTGAATTAGGAAACTTCTTCAGTCCAGAATTTATGAACCGTTTTGAT
GGTATTATTGAGTTCAAATCTCTTAGCAAGGAAAATCTCCTACAAATCGTAGATTTGATGCTTAAAGATGTCAATGAACG
GCTTGCCACGAATGACATTTACCTAGATGTAACAGATAAAGTCAAGGAAAAATTAGTTAATCTTGGTTACGATCCGAAAA
TGGGAGCTCGTCCACTTCGTCGGACAATCCAAGATCACATTGAGGATGCTATCACTGACTACTATCTTGAACATCCAAGC
GACAAAGAGCTCAAAGCTATCATGATAAGTAATGGTAAGATTGTCATCAAACCAGCTAAAAAATCTGAGAATAAATCCAA
GACAACAATAGATAACAATGCTAATTAG

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(154-273)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(648-722)

AAA lid domain (AAA_lid_9)

(292-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(477-640)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

86.497

99.073

0.857
  clpE Streptococcus pneumoniae D39

86.497

99.073

0.857
  clpE Streptococcus pneumoniae R6

86.497

99.073

0.857
  clpE Streptococcus pneumoniae TIGR4

86.497

99.073

0.857
  clpE Streptococcus mutans UA159

84.636

100

0.846
  clpC Lactococcus lactis subsp. cremoris KW2

76.79

99.868

0.767
  clpC Bacillus subtilis subsp. subtilis str. 168

51.493

88.742

0.457
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.546

86.358

0.411
  clpC Streptococcus pneumoniae Rx1

48.387

82.119

0.397
  clpC Streptococcus pneumoniae D39

48.387

82.119

0.397
  clpC Streptococcus pneumoniae TIGR4

48.226

82.119

0.396
  clpC Streptococcus thermophilus LMD-9

47.04

82.781

0.389
  clpC Streptococcus thermophilus LMG 18311

46.955

82.649

0.388
  clpC Streptococcus mutans UA159

47.173

81.987

0.387

Multiple sequence alignment