Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   LH706_RS12100 Genome accession   NZ_CP085043
Coordinates   2622834..2625377 (-) Length   847 a.a.
NCBI ID   WP_247394034.1    Uniprot ID   -
Organism   Ralstonia pseudosolanacearum strain RS638     
Function   DNA uptake (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2622834..2644080 2622834..2625377 within 0


Gene organization within MGE regions


Location: 2622834..2644080
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LH706_RS12100 (LH706_12115) comA 2622834..2625377 (-) 2544 WP_247394034.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  LH706_RS12105 (LH706_12120) - 2625387..2626202 (-) 816 WP_071015028.1 TatD family hydrolase -
  LH706_RS12110 (LH706_12125) lolD 2626231..2626965 (-) 735 WP_011001068.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  LH706_RS12115 (LH706_12130) - 2626958..2628208 (-) 1251 WP_011001067.1 lipoprotein-releasing ABC transporter permease subunit -
  LH706_RS12120 (LH706_12135) - 2628281..2629360 (+) 1080 WP_020831663.1 Regulatory protein, RpfE type -
  LH706_RS12125 (LH706_12140) recJ 2629361..2631058 (+) 1698 WP_221743422.1 single-stranded-DNA-specific exonuclease RecJ -
  LH706_RS12130 (LH706_12145) fdxA 2631229..2631555 (+) 327 WP_011001064.1 ferredoxin FdxA -
  LH706_RS12140 (LH706_12155) - 2631917..2633029 (+) 1113 WP_058907060.1 site-specific integrase -
  LH706_RS12145 (LH706_12160) - 2633263..2633481 (+) 219 WP_058907061.1 hypothetical protein -
  LH706_RS12150 (LH706_12165) - 2633498..2633833 (+) 336 WP_265069425.1 hypothetical protein -
  LH706_RS12155 (LH706_12170) - 2633830..2635413 (+) 1584 WP_265069426.1 phage/plasmid primase, P4 family -
  LH706_RS12160 (LH706_12175) - 2635530..2635829 (+) 300 WP_265069427.1 helix-turn-helix domain-containing protein -
  LH706_RS12165 (LH706_12180) - 2636149..2637090 (+) 942 WP_265069428.1 hypothetical protein -
  LH706_RS12170 (LH706_12185) - 2637090..2637464 (+) 375 WP_265069429.1 hypothetical protein -
  LH706_RS12175 (LH706_12190) - 2637467..2637649 (+) 183 WP_265069430.1 hypothetical protein -
  LH706_RS12180 (LH706_12195) - 2637788..2638006 (+) 219 WP_265069431.1 hypothetical protein -
  LH706_RS12185 (LH706_12200) - 2638009..2638206 (+) 198 WP_265069432.1 hypothetical protein -
  LH706_RS12190 (LH706_12205) - 2638203..2638415 (+) 213 WP_058907069.1 hypothetical protein -
  LH706_RS12195 (LH706_12210) - 2638412..2638756 (+) 345 WP_248139048.1 hypothetical protein -
  LH706_RS12200 (LH706_12215) - 2638753..2638965 (+) 213 WP_265069433.1 hypothetical protein -
  LH706_RS12205 (LH706_12220) - 2639002..2639229 (+) 228 WP_265069434.1 hypothetical protein -
  LH706_RS12210 (LH706_12225) - 2639285..2639668 (-) 384 WP_265069435.1 hypothetical protein -
  LH706_RS12215 (LH706_12230) - 2639799..2640668 (+) 870 WP_265069436.1 ComEC/Rec2 family competence protein -
  LH706_RS12220 (LH706_12235) - 2640740..2641309 (+) 570 WP_265069437.1 hypothetical protein -
  LH706_RS12230 (LH706_12245) - 2641695..2642429 (-) 735 WP_247394075.1 thioredoxin family protein -
  LH706_RS12235 (LH706_12250) - 2642517..2643011 (+) 495 WP_028852895.1 MarR family winged helix-turn-helix transcriptional regulator -
  LH706_RS12240 (LH706_12255) - 2642980..2644080 (-) 1101 WP_247394077.1 YeiH family protein -

Sequence

Protein


Download         Length: 847 a.a.        Molecular weight: 90903.79 Da        Isoelectric Point: 10.5253

>NTDB_id=614880 LH706_RS12100 WP_247394034.1 2622834..2625377(-) (comA) [Ralstonia pseudosolanacearum strain RS638]
MRALLIGFVAGCMALQTRPALAPVWQPALLGLACLLAMALLRRGARLPRLVPVMAALVAACAGFGWSDWRAQQRLSVVLA
PAWEGKDIRATGVVAELPEVTEDATRFLFRIESSDAGDAVPPRVRLSWYGLRSWHERQREAEAATDRRAGIPDLQPGQRW
QLTLRLKRPHSLMNPGGFDGEYAMLADDVRAAGYVYTGKRARNALMGEADAGSGVGLRVERWRAAVRRHLLAALPEARYA
PVIVALVVGDQSGIAQADWERFRRTGISHLVSISGLHITMIAGLFGALWMALWRRSFGLARWLRTPLPLRMPAQRAGAVA
AMAAAFAYCLLAGMGVPAQRTLLMLATVAVARLADRSVPVSLSLCWAAALVALVDPWAVMSAGGWLSFGAVAVIFLVARI
VAADARDDVRRPAWPVRAWRGLRGAARVQLAVTFGLLPLTLLLFQQVSVVSAVANALAIPVVSFVTTPLALMGTALPEPW
SQPLLIWAEASFAWLMPWLDALALPGGSVWVAPAAPAWAWGLAVVGVPLLLVPGGYRAWAWRAQGAVLLLPMLLARAPAP
PPGEFRMVAFDIGQGAATLVETAGHRLLFDTGPRQGDLADAADRVIVPYLRGHGVQAIDTLVVSHEDSDHAGGTETVMAG
VPVRTMLASLPPGHRLERQARALGIEPAGCVAGQRWAWDGVAFEILYPVQVPSDRAAVSSNARSCVLRIANARYAAMLAG
DIGRAQEAALIAAEAPERLMADILLVPHHGSRTSSSGAFLDAVSPQVAVFQVGYRNRYGHPHPQVWQRYGARGIERLRTD
ATGAVVIETRGDALAVRTARSMRPRYWSSALEVAALAETTEPTGAQP

Nucleotide


Download         Length: 2544 bp        

>NTDB_id=614880 LH706_RS12100 WP_247394034.1 2622834..2625377(-) (comA) [Ralstonia pseudosolanacearum strain RS638]
ATGCGCGCCCTGCTGATCGGCTTCGTCGCGGGGTGCATGGCGCTGCAGACGCGGCCGGCGCTGGCGCCGGTGTGGCAGCC
GGCGCTGCTTGGGCTCGCTTGCCTGCTGGCGATGGCGTTGCTGCGGCGCGGCGCTCGGTTGCCCAGGCTCGTTCCCGTGA
TGGCCGCGCTGGTGGCGGCCTGCGCCGGCTTCGGCTGGAGCGATTGGCGCGCGCAGCAGCGCTTGTCCGTGGTGCTGGCG
CCCGCATGGGAGGGCAAGGACATCCGCGCGACGGGCGTCGTGGCCGAGCTGCCCGAGGTCACCGAGGACGCCACGCGCTT
CCTGTTCCGGATTGAATCCAGCGACGCGGGCGATGCCGTACCGCCGCGCGTGCGGCTGTCGTGGTACGGCCTGCGCAGCT
GGCATGAGCGGCAGCGGGAGGCGGAGGCCGCCACCGATCGCCGCGCCGGCATTCCCGATCTGCAGCCCGGCCAGCGCTGG
CAGCTGACGCTGCGGCTCAAGCGGCCGCACAGCCTGATGAATCCCGGCGGCTTCGATGGCGAATACGCGATGCTTGCCGA
CGATGTCCGTGCCGCGGGCTACGTGTACACGGGCAAACGCGCGCGCAATGCGTTGATGGGCGAAGCCGATGCCGGTTCCG
GTGTTGGGCTCCGTGTCGAGCGCTGGCGCGCCGCGGTGCGGCGGCACCTCCTGGCTGCGCTGCCCGAGGCACGCTACGCG
CCGGTGATCGTCGCGCTGGTGGTGGGCGACCAGAGCGGCATCGCGCAGGCGGATTGGGAGCGCTTCCGCCGCACCGGCAT
CAGCCATCTCGTCAGCATTTCCGGTCTGCACATCACGATGATCGCCGGGCTGTTCGGCGCACTGTGGATGGCGCTGTGGC
GGCGCTCGTTCGGCCTGGCCCGCTGGCTGCGCACACCGCTGCCGCTGCGCATGCCGGCCCAGCGTGCGGGCGCCGTCGCC
GCCATGGCGGCGGCGTTTGCCTATTGCCTGCTGGCGGGGATGGGCGTGCCGGCGCAGCGCACGCTGCTGATGCTCGCGAC
CGTTGCCGTGGCGCGGCTGGCCGATCGCAGCGTGCCGGTCAGCCTGTCGCTGTGCTGGGCGGCGGCCTTGGTGGCGCTGG
TGGATCCGTGGGCGGTCATGTCGGCGGGAGGCTGGCTGTCGTTCGGCGCCGTGGCGGTCATCTTCCTGGTCGCGCGGATC
GTTGCCGCCGATGCGCGGGACGACGTCCGCCGGCCCGCCTGGCCGGTGCGCGCCTGGCGCGGCCTGCGCGGCGCCGCGCG
CGTCCAGCTGGCCGTGACGTTCGGCCTGCTGCCGTTGACCTTGCTGCTGTTCCAGCAGGTCTCGGTGGTGTCGGCCGTGG
CCAACGCGCTGGCGATCCCGGTGGTCAGCTTTGTCACGACGCCGCTGGCGCTGATGGGCACGGCGTTGCCCGAGCCATGG
TCGCAGCCGCTGCTGATATGGGCCGAGGCCAGCTTCGCCTGGCTCATGCCGTGGCTGGATGCGCTGGCGCTGCCCGGCGG
GTCGGTGTGGGTGGCGCCCGCCGCGCCGGCCTGGGCCTGGGGGCTGGCGGTGGTCGGTGTGCCGTTGCTGCTCGTGCCGG
GCGGGTATCGCGCCTGGGCCTGGCGGGCGCAGGGCGCGGTGCTGCTGCTGCCGATGCTGCTGGCACGCGCACCGGCGCCG
CCGCCGGGCGAGTTCCGCATGGTCGCATTCGACATCGGCCAGGGCGCCGCCACGCTGGTCGAGACGGCCGGCCACCGGCT
GCTGTTCGATACCGGTCCCCGCCAAGGCGACCTGGCCGATGCCGCCGATCGCGTGATCGTCCCGTATCTGCGCGGACATG
GGGTGCAGGCCATCGACACGCTGGTGGTCAGCCATGAGGACAGCGATCACGCCGGCGGCACCGAAACGGTGATGGCCGGT
GTGCCGGTGCGCACCATGCTGGCGTCCCTGCCGCCCGGCCACCGGCTGGAGCGGCAGGCCCGCGCGCTCGGCATCGAGCC
CGCCGGCTGCGTGGCCGGGCAGCGCTGGGCATGGGACGGCGTCGCCTTCGAAATCCTGTATCCGGTGCAGGTGCCCTCCG
ATCGGGCGGCCGTGTCCAGCAATGCCCGCAGCTGTGTGCTGCGCATCGCCAACGCGCGCTACGCCGCCATGCTGGCCGGC
GACATCGGCCGCGCCCAGGAAGCGGCGCTGATTGCCGCCGAAGCGCCGGAGCGGCTCATGGCAGATATCTTGCTTGTGCC
CCATCATGGCAGCAGGACGAGCTCCAGCGGCGCGTTCCTGGACGCGGTCTCGCCGCAGGTGGCGGTGTTCCAGGTCGGCT
ACCGCAACCGGTACGGTCATCCGCATCCGCAGGTCTGGCAGCGCTACGGCGCGCGCGGCATCGAGCGGCTGCGCACCGAT
GCCACCGGGGCCGTCGTCATCGAGACGCGCGGCGATGCGCTGGCGGTGCGGACGGCGCGGTCGATGCGGCCGCGCTACTG
GTCCTCGGCGCTGGAGGTGGCCGCCCTGGCAGAGACCACGGAGCCCACGGGCGCGCAGCCGTAA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(246-532)

Domain of unknown function (DUF4131) (DUF4131)

(24-198)

Beta-lactamase superfamily domain (Lactamase_B_2)

(585-745)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Ralstonia pseudosolanacearum GMI1000

99.292

100

0.993