Detailed information NTG0614742

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: NQZ84_RS10300
• Genome accession: NZ_CP102094
• Coordinates: 2127889..2130429 (-)
• Length: 846 a.a.
• NCBI ID: WP_044694067.1
• Uniprot ID: -
• Organism: Streptococcus suis strain 12RC1
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2122889..2135429

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQZ84_RS10260 (NQZ84_10260)	-	2123271..2124014 (-)	744	WP_013730659.1	amino acid ABC transporter ATP-binding protein	-
NQZ84_RS10265 (NQZ84_10265)	-	2124014..2124817 (-)	804	WP_024407716.1	amino acid ABC transporter permease	-
NQZ84_RS10270 (NQZ84_10270)	-	2125003..2125854 (-)	852	WP_257047596.1	amino acid ABC transporter substrate-binding protein	-
NQZ84_RS10280 (NQZ84_10280)	-	2125887..2126494 (-)	608	Protein_1992	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	-
NQZ84_RS10285 (NQZ84_10285)	-	2126670..2126843 (-)	174	WP_002941962.1	hypothetical protein	-
NQZ84_RS10290 (NQZ84_10290)	-	2126877..2127317 (-)	441	WP_024409072.1	DUF3021 domain-containing protein	-
NQZ84_RS10295 (NQZ84_10295)	-	2127314..2127757 (-)	444	WP_024409071.1	LytTR family DNA-binding domain-containing protein	-
NQZ84_RS10300 (NQZ84_10300)	hexA	2127889..2130429 (-)	2541	WP_044694067.1	DNA mismatch repair protein MutS	Machinery gene
NQZ84_RS10305 (NQZ84_10305)	argR	2130444..2130884 (-)	441	WP_002937036.1	arginine repressor	-
NQZ84_RS10310 (NQZ84_10310)	argS	2130991..2132679 (+)	1689	WP_015647550.1	arginine--tRNA ligase	-
NQZ84_RS10315 (NQZ84_10315)	-	2132859..2133773 (+)	915	WP_257047593.1	SH3 domain-containing protein	-
NQZ84_RS10320 (NQZ84_10320)	-	2133827..2134351 (-)	525	WP_024384267.1	ABC transporter permease	-
NQZ84_RS10325 (NQZ84_10325)	-	2134463..2134645 (+)	183	WP_015647552.1	hypothetical protein	-

Sequence

Protein

• Length: 846 a.a.
• Molecular weight: 95064.47 Da
• Isoelectric Point: 4.7721

>NTDB_id=614742 NQZ84_RS10300 WP_044694067.1 2127889..2130429(-) (hexA) [Streptococcus suis strain 12RC1]
MATEKISPGMQQYLDIKAQYPDAFLLFRMGDFYELFYEDAVEAAQILELSLTSRNKNAENPIPMAGVPYHAAQQYIDTLV
ELGHKVAIAEQMEDPKQAVGVVKREVVQVITPGTVTDSSKMGADSNYLVAIDRQGVQFALSYMDVSTGQFFVTSLDDFTS
LCGEIRNLRARELVIGYALSEEEEQVFSNQMNLLLSFEDEVTEDVQLIDNSLTDLEKAAAGKLLSYLHRTQMRDLSHLQK
VVHYEIKDYLQMDYATKSSLDLLENGRTGKKHGSLYWLLDETKTAMGMRLLRTWIDRPLIDLKRIENRQAVVQVFLDYFF
ERSDLVEALKGVYDIERLASRVSFGKTMPKDLLQLSQTLGNIPAIKNILQQINEPALGNLVAGLDPIPELHALISSAIDP
EAQGTITDGNIIRTGFDETLDQYRLVMREGAGWIAEIEAKEREASGINNLKIDYNKKDGYYFHVTNSNLGNVPDHFFRKA
TLKNSERYGTEELAKIEGQMLEARDKSANLEYEIFMRIRQEVEKYIGRLQKLARTIATIDVLQAFAVVAEQQHLVCPRFT
DQRELTIDRGRHAVVEKVMGKQTYIPNSIHLDTDTHMQLITGPNMSGKSTYMRQLAVIVIMAQMGSYVPADQAELPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANKAVRLATDRSLILFDELGRGTATYDGMALAQSIIEYIHDKIGAKTLFATHYHEL
TDLSQTLEHLENVHVSTLEKDGQVTFLHKIAQGPADKSYGIHVAKIAGMPEELLQRADRILQTLENQAPTAPANPAPSVV
EEPSGQIDLFADTPSHPVLDELEKLDIYNMTPMEVMMAVAELKKKI

Nucleotide

• Length: 2541 bp

>NTDB_id=614742 NQZ84_RS10300 WP_044694067.1 2127889..2130429(-) (hexA) [Streptococcus suis strain 12RC1]
ATGGCAACAGAAAAAATTTCTCCGGGAATGCAGCAGTATCTGGATATAAAAGCACAGTATCCAGATGCTTTTTTGCTTTT
CCGTATGGGAGACTTTTATGAGTTATTTTATGAAGATGCGGTAGAGGCTGCACAGATTTTGGAATTGTCCTTGACCAGTC
GGAATAAGAATGCGGAAAATCCGATTCCTATGGCGGGGGTACCGTATCACGCGGCACAACAGTATATCGACACACTTGTT
GAATTGGGGCACAAGGTCGCAATTGCCGAGCAGATGGAAGATCCTAAGCAGGCAGTCGGCGTGGTCAAGCGAGAAGTAGT
GCAGGTCATTACTCCTGGTACGGTAACAGACTCGTCCAAAATGGGAGCAGACAGTAACTATTTGGTTGCGATTGACCGTC
AGGGAGTGCAGTTCGCACTTTCTTATATGGATGTGTCAACAGGTCAGTTTTTTGTGACTAGTTTGGATGATTTTACTAGT
CTTTGCGGTGAGATCCGCAATTTACGGGCACGTGAATTAGTCATCGGCTACGCTTTATCTGAGGAAGAAGAGCAGGTCTT
TTCGAACCAGATGAACCTCCTGCTCTCTTTTGAGGATGAGGTGACGGAAGATGTCCAGCTGATTGACAACTCCTTGACAG
ACTTGGAAAAGGCTGCGGCAGGGAAACTCCTCAGCTACCTACATCGGACTCAGATGCGAGATCTGAGCCACTTGCAAAAG
GTGGTCCACTATGAAATCAAGGACTATCTACAAATGGACTATGCAACCAAGTCCAGTCTGGATCTGCTTGAAAACGGTCG
GACAGGCAAGAAGCATGGTAGTTTGTACTGGTTGCTAGACGAAACTAAGACAGCCATGGGTATGCGACTATTGCGGACAT
GGATTGATCGTCCCTTGATTGATCTTAAGCGGATTGAGAATCGTCAGGCTGTCGTTCAGGTTTTTCTGGATTACTTCTTT
GAACGGAGTGACTTGGTCGAGGCTTTAAAAGGTGTCTATGACATCGAACGCTTGGCCAGCCGGGTGTCTTTTGGAAAAAC
CATGCCCAAGGATCTCTTGCAGCTCTCCCAGACTCTGGGAAATATCCCAGCAATCAAGAATATCTTGCAACAAATCAATG
AGCCTGCTCTAGGCAATCTGGTAGCTGGATTGGACCCAATCCCAGAACTGCACGCTCTCATCAGCTCTGCTATTGACCCA
GAAGCCCAAGGGACCATCACAGATGGAAACATCATCCGTACAGGCTTTGACGAAACGCTGGATCAGTATCGTCTGGTCAT
GCGTGAGGGAGCGGGTTGGATTGCGGAGATTGAGGCCAAGGAGCGTGAAGCGTCTGGTATCAACAATCTTAAGATTGATT
ACAACAAAAAAGACGGTTACTATTTCCATGTGACCAATTCCAATCTGGGTAATGTGCCGGACCATTTTTTCCGTAAGGCG
ACCTTGAAAAACTCGGAGCGCTATGGAACGGAAGAGTTGGCTAAGATCGAAGGGCAGATGTTGGAGGCGCGTGATAAGTC
TGCTAATTTGGAGTATGAGATTTTCATGCGGATTCGCCAAGAGGTTGAGAAGTATATCGGTCGCTTGCAGAAGCTGGCTC
GGACTATTGCAACCATCGATGTTTTGCAGGCCTTTGCAGTTGTGGCGGAGCAGCAACATTTGGTTTGTCCACGTTTTACA
GATCAAAGAGAACTGACCATTGACCGTGGTCGTCATGCGGTGGTGGAGAAGGTCATGGGCAAGCAGACCTACATTCCCAA
CTCTATTCACTTGGATACCGATACGCATATGCAACTGATTACTGGTCCAAACATGAGTGGTAAGTCTACCTATATGCGAC
AGTTGGCGGTTATCGTCATCATGGCGCAGATGGGTTCCTATGTACCTGCGGATCAGGCTGAATTACCGATTTTCGATGCT
ATTTTCACCCGAATTGGGGCGGCAGACGACTTGGTTAGTGGTCAATCGACCTTCATGGTCGAAATGATGGAGGCCAATAA
GGCAGTCCGTCTGGCGACAGATCGGTCGCTCATCCTCTTTGATGAGTTGGGACGGGGAACGGCCACCTATGACGGTATGG
CTCTGGCTCAGTCTATCATCGAGTACATCCACGACAAGATTGGAGCCAAGACCCTCTTTGCTACCCACTACCATGAGTTG
ACAGACCTTAGCCAGACCTTGGAACACCTAGAGAATGTCCATGTATCGACCTTGGAGAAGGACGGCCAAGTCACCTTCCT
CCACAAGATTGCCCAAGGTCCAGCTGACAAGTCCTACGGGATTCATGTGGCTAAGATTGCGGGAATGCCAGAGGAACTAT
TGCAGCGGGCGGATAGGATTTTGCAGACGCTTGAAAACCAAGCCCCTACTGCACCAGCTAATCCAGCACCGTCAGTAGTG
GAAGAGCCGTCTGGTCAAATCGACCTCTTCGCAGACACGCCTTCTCACCCAGTCCTTGATGAACTGGAAAAACTAGACAT
CTACAATATGACTCCTATGGAAGTCATGATGGCAGTGGCGGAGTTGAAGAAAAAAATATAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (599-785)

• MutS domain III (MutS_III) (256-546)

• MutS domain I (MutS_I) (8-118)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-505)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.995	100	0.74
mutS	Pseudomonas stutzeri strain ATCC 17587	37.863	100	0.385