Detailed information NTG0061436

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SAKOR_RS13455
• Genome accession: NC_022226
• Coordinates: 2650341..2651228 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus subsp. aureus CN1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2645341..2656228

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAKOR_RS13420	-	2645359..2645451 (+)	93	WP_010956583.1	hypothetical protein	-
SAKOR_RS13425 (SAKOR_02617)	-	2645559..2646056 (-)	498	WP_001065269.1	glutathione peroxidase	-
SAKOR_RS13430 (SAKOR_02618)	-	2646066..2646326 (-)	261	WP_001789910.1	hypothetical protein	-
SAKOR_RS13435	-	2646708..2646821 (-)	114	Protein_2558	hypothetical protein	-
SAKOR_RS13445 (SAKOR_02620)	-	2647480..2649480 (-)	2001	WP_000776739.1	ABC transporter permease	-
SAKOR_RS13450 (SAKOR_02621)	-	2649477..2650232 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SAKOR_RS13455 (SAKOR_02622)	braS	2650341..2651228 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SAKOR_RS13460 (SAKOR_02623)	braR	2651239..2651904 (-)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SAKOR_RS13465 (SAKOR_02624)	-	2651930..2652130 (-)	201	WP_000604727.1	hypothetical protein	-
SAKOR_RS13475 (SAKOR_02625)	-	2652328..2653752 (+)	1425	WP_000953762.1	alkaline phosphatase	-
SAKOR_RS14945 (SAKOR_02627)	-	2653821..2653931 (+)	111	WP_001791296.1	hypothetical protein	-
SAKOR_RS13480 (SAKOR_02628)	-	2654034..2654489 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SAKOR_RS13485 (SAKOR_02629)	-	2654734..2655495 (-)	762	WP_000323447.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=61436 SAKOR_RS13455 WP_000143420.1 2650341..2651228(-) (braS) [Staphylococcus aureus subsp. aureus CN1]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=61436 SAKOR_RS13455 WP_000143420.1 2650341..2651228(-) (braS) [Staphylococcus aureus subsp. aureus CN1]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993