Detailed information NTG0061430

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SAKOR_RS09495
• Genome accession: NC_022226
• Coordinates: 1906679..1907722 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus subsp. aureus CN1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1901679..1912722

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAKOR_RS09465 (SAKOR_01835)	-	1902101..1903357 (-)	1257	WP_001789555.1	aminopeptidase	-
SAKOR_RS09470 (SAKOR_01836)	-	1903360..1903560 (-)	201	WP_000180460.1	DUF1128 family protein	-
SAKOR_RS09475 (SAKOR_01837)	-	1903707..1904171 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
SAKOR_RS09480 (SAKOR_01838)	-	1904178..1904453 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SAKOR_RS09485 (SAKOR_01839)	-	1904731..1905948 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
SAKOR_RS09490 (SAKOR_01840)	vraR	1906060..1906689 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
SAKOR_RS09495 (SAKOR_01841)	vraS	1906679..1907722 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SAKOR_RS09500 (SAKOR_01842)	liaF	1907719..1908420 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SAKOR_RS09505 (SAKOR_01843)	-	1908435..1908821 (-)	387	WP_001110179.1	hypothetical protein	-
SAKOR_RS09510 (SAKOR_01844)	map	1909038..1909796 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SAKOR_RS09520 (SAKOR_01846)	-	1910324..1911310 (+)	987	WP_000999714.1	aromatic acid exporter family protein	-
SAKOR_RS09525 (SAKOR_01848)	-	1911741..1912154 (-)	414	WP_025173836.1	hypothetical protein	-
SAKOR_RS09530 (SAKOR_01849)	-	1912183..1912293 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=61430 SAKOR_RS09495 WP_001017131.1 1906679..1907722(-) (vraS) [Staphylococcus aureus subsp. aureus CN1]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=61430 SAKOR_RS09495 WP_001017131.1 1906679..1907722(-) (vraS) [Staphylococcus aureus subsp. aureus CN1]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1