Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   EL334_RS06075 Genome accession   NZ_AP019192
Coordinates   1137778..1138242 (-) Length   154 a.a.
NCBI ID   WP_001135782.1    Uniprot ID   P59659
Organism   Streptococcus pneumoniae strain ASP0581     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1132778..1143242
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL334_RS06055 (ASP0581_11330) - 1133729..1134697 (-) 969 WP_033705551.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  EL334_RS06060 (ASP0581_11340) pdrM 1134851..1136212 (-) 1362 WP_000278537.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  EL334_RS06065 (ASP0581_11350) - 1136223..1136483 (-) 261 WP_001105925.1 hypothetical protein -
  EL334_RS06070 (ASP0581_11360) - 1136497..1137765 (-) 1269 WP_033705552.1 dihydroorotase -
  EL334_RS06075 (ASP0581_11370) mutX 1137778..1138242 (-) 465 WP_001135782.1 NUDIX hydrolase Machinery gene
  EL334_RS06080 (ASP0581_11380) - 1138252..1138905 (-) 654 WP_000401328.1 uracil-DNA glycosylase -
  EL334_RS06085 (ASP0581_11390) - 1139041..1139688 (-) 648 WP_050456368.1 hypothetical protein -
  EL334_RS06090 (ASP0581_11400) - 1139702..1140415 (-) 714 WP_033705553.1 YjjG family noncanonical pyrimidine nucleotidase -
  EL334_RS06095 (ASP0581_11410) dhaM 1140874..1141254 (-) 381 WP_033705554.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  EL334_RS12745 - 1141254..1141328 (-) 75 Protein_1150 dihydroxyacetone kinase subunit L -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17870.30 Da        Isoelectric Point: 4.2287

>NTDB_id=61424 EL334_RS06075 WP_001135782.1 1137778..1138242(-) (mutX) [Streptococcus pneumoniae strain ASP0581]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAVREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGMLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=61424 EL334_RS06075 WP_001135782.1 1137778..1138242(-) (mutX) [Streptococcus pneumoniae strain ASP0581]
ATGCCTCAGTTAGCGACGATTTGTTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGTACGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGATGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACCTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P59659

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

100

100

1

Multiple sequence alignment