Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | SAKOR_RS00235 | Genome accession | NC_022226 |
| Coordinates | 52847..54196 (-) | Length | 449 a.a. |
| NCBI ID | WP_002486033.1 | Uniprot ID | - |
| Organism | Staphylococcus aureus subsp. aureus CN1 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 24482..72895 | 52847..54196 | within | 0 |
| SCCmec | 42872..59366 | 52847..54196 | within | 0 |
Gene organization within MGE regions
Location: 24482..72895
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SAKOR_RS00100 (SAKOR_00018) | yycF | 24940..25641 (+) | 702 | WP_000101976.1 | response regulator YycF | - |
| SAKOR_RS00105 (SAKOR_00019) | walK | 25654..27480 (+) | 1827 | WP_000871607.1 | cell wall metabolism sensor histidine kinase WalK | - |
| SAKOR_RS00110 (SAKOR_00020) | yycH | 27473..28807 (+) | 1335 | WP_001060140.1 | two-component system activity regulator YycH | - |
| SAKOR_RS00115 (SAKOR_00021) | yycI | 28808..29596 (+) | 789 | WP_001104168.1 | two-component system regulatory protein YycI | - |
| SAKOR_RS00120 (SAKOR_00022) | - | 29985..30785 (+) | 801 | WP_000088649.1 | MBL fold metallo-hydrolase | - |
| SAKOR_RS00125 (SAKOR_00023) | adsA | 31013..33331 (+) | 2319 | WP_000645771.1 | LPXTG-anchored adenosine synthase AdsA | - |
| SAKOR_RS00135 (SAKOR_00024) | rlmH | 33699..34178 (+) | 480 | WP_020977937.1 | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH | - |
| SAKOR_RS00140 (SAKOR_00025) | - | 34500..35756 (+) | 1257 | WP_000566670.1 | DUF3578 domain-containing protein | - |
| SAKOR_RS00145 (SAKOR_00026) | - | 36171..36410 (+) | 240 | WP_001282728.1 | hypothetical protein | - |
| SAKOR_RS00150 (SAKOR_00027) | - | 36442..37116 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| SAKOR_RS00160 (SAKOR_00029) | - | 37207..38190 (-) | 984 | Protein_27 | protein rep | - |
| SAKOR_RS00165 (SAKOR_00031) | mobV | 38437..39699 (-) | 1263 | WP_029163598.1 | MobV family relaxase | - |
| SAKOR_RS00170 (SAKOR_00034) | bleO | 40206..40610 (-) | 405 | WP_001242578.1 | bleomycin binding protein | - |
| SAKOR_RS00175 (SAKOR_00035) | aadD1 | 40827..41597 (-) | 771 | WP_001795128.1 | aminoglycoside O-nucleotidyltransferase ANT(4')-Ia | - |
| SAKOR_RS00185 (SAKOR_00038) | - | 42521..42826 (+) | 306 | Protein_32 | MaoC/PaaZ C-terminal domain-containing protein | - |
| SAKOR_RS00190 (SAKOR_00039) | mecA | 42872..44881 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| SAKOR_RS00195 (SAKOR_00040) | - | 44978..45964 (+) | 987 | WP_001549960.1 | beta-lactam sensor/signal transducer MecR1 | - |
| SAKOR_RS00200 (SAKOR_00041) | - | 45936..46196 (+) | 261 | WP_001549961.1 | type I restriction enzyme endonuclease domain-containing protein | - |
| SAKOR_RS00205 (SAKOR_00042) | - | 46463..47662 (+) | 1200 | WP_073392450.1 | IS110-like element ISSep2 family transposase | - |
| SAKOR_RS00210 (SAKOR_00043) | - | 47759..49354 (-) | 1596 | Protein_37 | IS1182 family transposase | - |
| SAKOR_RS00215 (SAKOR_00044) | - | 49406..49912 (-) | 507 | WP_001092189.1 | DUF1643 domain-containing protein | - |
| SAKOR_RS00220 (SAKOR_00045) | - | 49927..50238 (-) | 312 | WP_000700851.1 | DUF960 family protein | - |
| SAKOR_RS00225 (SAKOR_00046) | - | 50325..50675 (-) | 351 | WP_000849672.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| SAKOR_RS00230 (SAKOR_00047) | ccrB | 51197..52825 (-) | 1629 | WP_001186608.1 | recombinase family protein | Machinery gene |
| SAKOR_RS00235 (SAKOR_00048) | ccrA | 52847..54196 (-) | 1350 | WP_002486033.1 | recombinase family protein | Machinery gene |
| SAKOR_RS00240 (SAKOR_00049) | - | 54430..56223 (-) | 1794 | WP_000079474.1 | DUF927 domain-containing protein | - |
| SAKOR_RS00245 (SAKOR_00050) | - | 56223..56519 (-) | 297 | WP_000273823.1 | single-stranded DNA-binding protein | - |
| SAKOR_RS00250 (SAKOR_00051) | - | 56712..57758 (-) | 1047 | WP_001042023.1 | hypothetical protein | - |
| SAKOR_RS14995 (SAKOR_00052) | - | 58213..58662 (+) | 450 | WP_001813878.1 | ATP-binding protein | - |
| SAKOR_RS15000 (SAKOR_00053) | - | 58773..59366 (+) | 594 | WP_001181652.1 | hypothetical protein | - |
| SAKOR_RS00265 (SAKOR_00054) | - | 59396..60196 (+) | 801 | WP_000749913.1 | abortive infection family protein | - |
| SAKOR_RS00270 (SAKOR_00055) | - | 60379..61314 (+) | 936 | WP_000251226.1 | dsDNA nuclease domain-containing protein | - |
| SAKOR_RS00275 (SAKOR_00056) | - | 61307..61915 (+) | 609 | WP_029163516.1 | hypothetical protein | - |
| SAKOR_RS00280 (SAKOR_00057) | - | 61912..62169 (+) | 258 | WP_020977950.1 | hypothetical protein | - |
| SAKOR_RS00285 (SAKOR_00058) | - | 62226..62978 (+) | 753 | WP_000417870.1 | hypothetical protein | - |
| SAKOR_RS00290 (SAKOR_00059) | - | 63225..64211 (-) | 987 | WP_000662022.1 | tRNA-dihydrouridine synthase | - |
| SAKOR_RS00295 (SAKOR_00060) | - | 64520..64723 (+) | 204 | WP_000398680.1 | DUF6007 family protein | - |
| SAKOR_RS00300 (SAKOR_00061) | - | 64772..65068 (+) | 297 | WP_000179888.1 | TfoX/Sxy family protein | - |
| SAKOR_RS00305 (SAKOR_00062) | - | 65277..65879 (+) | 603 | WP_000908959.1 | hypothetical protein | - |
| SAKOR_RS00310 (SAKOR_00063) | - | 66171..67085 (-) | 915 | WP_000814441.1 | alpha/beta hydrolase | - |
| SAKOR_RS00315 (SAKOR_00064) | - | 67264..67818 (+) | 555 | WP_020977952.1 | TetR/AcrR family transcriptional regulator C-terminal domain-containing protein | - |
| SAKOR_RS00320 (SAKOR_00066) | - | 68048..68785 (+) | 738 | WP_001792407.1 | methyltransferase domain-containing protein | - |
| SAKOR_RS00325 (SAKOR_00067) | - | 68941..69423 (+) | 483 | WP_000410569.1 | hypothetical protein | - |
| SAKOR_RS00330 (SAKOR_00068) | - | 69629..70615 (+) | 987 | WP_000710561.1 | phosphatidylinositol-specific phospholipase C | - |
| SAKOR_RS00335 | - | 70836..71605 (+) | 770 | Protein_62 | tandem-type lipoprotein | - |
| SAKOR_RS00340 (SAKOR_00071) | - | 71672..72439 (+) | 768 | WP_000649985.1 | tandem-type lipoprotein | - |
Sequence
Protein
Download Length: 449 a.a. Molecular weight: 52614.32 Da Isoelectric Point: 9.9100
>NTDB_id=61397 SAKOR_RS00235 WP_002486033.1 52847..54196(-) (ccrA) [Staphylococcus aureus subsp. aureus CN1]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQLTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYDYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRSQKQTKQTSSDNQLKQKIKCPCCNATLTNMTVRKKNHILRYYVCPKNMNASRFVCDFKGINAQTLEDKVLKV
CQDFYQDQHIYVKIKNAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFRKQMQSLHQQPQRITSISEHQIQHTIQ
NIIQKRFTLNILYPYIETIHIAKDKNLIGIYFKNEPLNIVNQTMQSSIA
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQLTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYDYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRSQKQTKQTSSDNQLKQKIKCPCCNATLTNMTVRKKNHILRYYVCPKNMNASRFVCDFKGINAQTLEDKVLKV
CQDFYQDQHIYVKIKNAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFRKQMQSLHQQPQRITSISEHQIQHTIQ
NIIQKRFTLNILYPYIETIHIAKDKNLIGIYFKNEPLNIVNQTMQSSIA
Nucleotide
Download Length: 1350 bp
>NTDB_id=61397 SAKOR_RS00235 WP_002486033.1 52847..54196(-) (ccrA) [Staphylococcus aureus subsp. aureus CN1]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAATTAACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACGTACCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACACATGCACCTTTTGGTTACGATTATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGCCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATCGCAAAAACAAACCAAACAGACATCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCGTTAGAAAAAAGAATCATATATTACGTTACTACGTCTGTCCTA
AAAATATGAATGCTTCACGCTTTGTCTGTGATTTCAAAGGCATCAATGCACAGACATTGGAAGATAAAGTATTAAAAGTG
TGCCAAGACTTTTATCAAGACCAACATATCTACGTAAAAATTAAAAATGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAGCATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATCGATGCAGAAACGTTTA
GAAAACAAATGCAATCATTACATCAACAACCACAACGCATCACATCCATCAGTGAGCATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTGCGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCAATTGCATAA
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAATTAACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACGTACCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACACATGCACCTTTTGGTTACGATTATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGCCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATCGCAAAAACAAACCAAACAGACATCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCGTTAGAAAAAAGAATCATATATTACGTTACTACGTCTGTCCTA
AAAATATGAATGCTTCACGCTTTGTCTGTGATTTCAAAGGCATCAATGCACAGACATTGGAAGATAAAGTATTAAAAGTG
TGCCAAGACTTTTATCAAGACCAACATATCTACGTAAAAATTAAAAATGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAGCATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATCGATGCAGAAACGTTTA
GAAAACAAATGCAATCATTACATCAACAACCACAACGCATCACATCCATCAGTGAGCATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTGCGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCAATTGCATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus N315 |
95.546 |
100 |
0.955 |
| ccrA | Staphylococcus aureus COL |
74.833 |
100 |
0.748 |