Detailed information NTG0613757

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: LD199_RS12850
• Genome accession: NZ_CP084878
• Coordinates: 2615714..2616601 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain GS426
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2610714..2621601

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LD199_RS12820 (LD199_12820)	-	2610733..2610825 (+)	93	WP_010956583.1	hypothetical protein	-
LD199_RS12825 (LD199_12825)	-	2610933..2611430 (-)	498	WP_001065268.1	glutathione peroxidase	-
LD199_RS12830 (LD199_12830)	-	2611440..2611700 (-)	261	WP_001791974.1	hypothetical protein	-
LD199_RS12835 (LD199_12835)	-	2612082..2612195 (-)	114	Protein_2484	hypothetical protein	-
LD199_RS12840 (LD199_12840)	-	2612854..2614854 (-)	2001	WP_000776751.1	ABC transporter permease	-
LD199_RS12845 (LD199_12845)	-	2614851..2615606 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
LD199_RS12850 (LD199_12850)	braS	2615714..2616601 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
LD199_RS12855 (LD199_12855)	braR	2616612..2617277 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
LD199_RS12860 (LD199_12860)	-	2617303..2617503 (-)	201	WP_000604730.1	hypothetical protein	-
LD199_RS12865 (LD199_12865)	-	2617701..2619125 (+)	1425	WP_000953755.1	alkaline phosphatase	-
LD199_RS13135	-	2619185..2619286 (-)	102	WP_000731976.1	SE2200 family small protein	-
LD199_RS12875 (LD199_12875)	-	2619408..2619863 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
LD199_RS12880 (LD199_12880)	-	2620108..2620869 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=613757 LD199_RS12850 WP_000143425.1 2615714..2616601(-) (braS) [Staphylococcus aureus strain GS426]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=613757 LD199_RS12850 WP_000143425.1 2615714..2616601(-) (braS) [Staphylococcus aureus strain GS426]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1