Detailed information    

insolico Bioinformatically predicted

Overview

Name   sxy/tfoX   Type   Regulator
Locus tag   LGL99_RS15695 Genome accession   NZ_CP084873
Coordinates   3186767..3187363 (-) Length   198 a.a.
NCBI ID   WP_004179217.1    Uniprot ID   A0A085DH59
Organism   Klebsiella pneumoniae strain 03-9138-2     
Function   positive regulator of competence gene (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 3172814..3189644 3186767..3187363 within 0


Gene organization within MGE regions


Location: 3172814..3189644
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LGL99_RS15625 (LGL99_15625) - 3172814..3173479 (+) 666 WP_004224043.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
  LGL99_RS15630 (LGL99_15630) - 3173489..3175168 (+) 1680 WP_004224042.1 ADP-ribosylglycohydrolase family protein -
  LGL99_RS15635 (LGL99_15635) - 3175417..3176383 (-) 967 Protein_3073 IS3 family transposase -
  LGL99_RS15640 (LGL99_15640) - 3176450..3177318 (+) 869 Protein_3074 IS110 family transposase -
  LGL99_RS15645 (LGL99_15645) - 3177544..3177630 (-) 87 Protein_3075 hypothetical protein -
  LGL99_RS15650 (LGL99_15650) - 3177777..3178565 (-) 789 WP_002898450.1 AraC family transcriptional regulator -
  LGL99_RS15655 (LGL99_15655) - 3178583..3179137 (-) 555 WP_004210995.1 YbhB/YbcL family Raf kinase inhibitor-like protein -
  LGL99_RS15660 (LGL99_15660) rlmI 3179328..3180530 (+) 1203 WP_226618811.1 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI -
  LGL99_RS15665 (LGL99_15665) hspQ 3180590..3180907 (+) 318 WP_002898441.1 heat shock protein HspQ -
  LGL99_RS15670 (LGL99_15670) - 3180937..3181350 (-) 414 WP_004144085.1 CoA-binding protein -
  LGL99_RS15675 (LGL99_15675) mgsA 3181505..3181963 (+) 459 WP_004224034.1 methylglyoxal synthase -
  LGL99_RS15680 (LGL99_15680) helD 3181975..3184029 (-) 2055 WP_004224033.1 DNA helicase IV -
  LGL99_RS15685 (LGL99_15685) - 3184154..3184600 (+) 447 WP_004224032.1 YccF domain-containing protein -
  LGL99_RS15690 (LGL99_15690) yccS 3184618..3186753 (+) 2136 WP_002898422.1 YccS family putative transporter -
  LGL99_RS15695 (LGL99_15695) sxy/tfoX 3186767..3187363 (-) 597 WP_004179217.1 TfoX/Sxy family DNA transformation protein Regulator
  LGL99_RS15700 (LGL99_15700) sulA 3187712..3188221 (+) 510 WP_002898418.1 SOS-induced cell division inhibitor SulA -
  LGL99_RS15705 (LGL99_15705) ompA 3188574..3189644 (+) 1071 WP_002898408.1 porin OmpA -

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 22516.11 Da        Isoelectric Point: 10.0350

>NTDB_id=613661 LGL99_RS15695 WP_004179217.1 3186767..3187363(-) (sxy/tfoX) [Klebsiella pneumoniae strain 03-9138-2]
MRKLVCPRLPQFQACVSPLGQLHTRPLFGGYSLAIDDTVFAMVAEGNIYLKACEQSAAYRVEHRNPLLTLRRHGRIVPLK
YYQIDDTLWRDEQQLFRLSLLSWQSAQREKNCRRASGRLKDLPNISFHMELQLIHAGIPDVRTLREVGAQEAWLRLRVNN
ASLSLSVLLALEGAIAGVHAAALPTPRRQELLEWAATR

Nucleotide


Download         Length: 597 bp        

>NTDB_id=613661 LGL99_RS15695 WP_004179217.1 3186767..3187363(-) (sxy/tfoX) [Klebsiella pneumoniae strain 03-9138-2]
ATGAGAAAACTAGTTTGTCCGCGGCTCCCGCAATTTCAGGCCTGCGTCTCACCGCTGGGTCAACTGCATACTCGTCCGCT
CTTTGGCGGCTACAGCCTGGCTATTGATGATACGGTGTTTGCGATGGTGGCCGAGGGAAACATTTATCTGAAGGCCTGCG
AGCAGAGCGCTGCTTATCGGGTGGAACATCGTAATCCTCTGTTAACGCTGCGCCGACACGGCCGCATAGTGCCGCTGAAG
TATTATCAAATTGACGACACTTTATGGCGCGATGAGCAGCAGCTTTTTCGGCTATCGCTACTGTCGTGGCAGAGTGCGCA
GCGCGAAAAGAACTGCCGACGGGCGTCGGGCCGCCTGAAGGATTTACCCAATATCAGCTTTCATATGGAATTGCAGCTGA
TTCACGCGGGCATACCGGACGTTAGGACGTTGCGGGAAGTTGGTGCGCAGGAGGCATGGCTGAGGCTACGCGTAAATAAT
GCTTCTTTATCGCTGAGCGTATTGCTGGCGCTGGAGGGGGCGATTGCCGGGGTACATGCCGCCGCGCTCCCGACGCCACG
GCGTCAGGAGCTTCTCGAATGGGCGGCTACCCGGTAG

Domains

Predicted by InterproScan.

TfoX C-terminal domain (TfoX_C)

(117-194)

TfoX N-terminal domain (TfoX_N)

(16-105)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A085DH59

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sxy/tfoX Escherichia coli BW25113 strain K-12

51.269

99.495

0.51