Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexA   Type   Machinery gene
Locus tag   NPS18_RS06930 Genome accession   NZ_CP101984
Coordinates   1423142..1426780 (-) Length   1212 a.a.
NCBI ID   WP_002262919.1    Uniprot ID   Q8DT76
Organism   Streptococcus mutans strain UA-159     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1418142..1431780
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS18_RS06900 (NPS18_06900) lacF 1418623..1418937 (-) 315 WP_002263056.1 PTS lactose transporter subunit IIA -
  NPS18_RS06905 (NPS18_06905) lacD 1418953..1419930 (-) 978 WP_002277661.1 tagatose-bisphosphate aldolase -
  NPS18_RS06910 (NPS18_06910) lacC 1419935..1420867 (-) 933 WP_002262465.1 tagatose-6-phosphate kinase -
  NPS18_RS06915 (NPS18_06915) lacB 1420886..1421401 (-) 516 WP_002262464.1 galactose-6-phosphate isomerase subunit LacB -
  NPS18_RS06920 (NPS18_06920) lacA 1421427..1421855 (-) 429 WP_002262463.1 galactose-6-phosphate isomerase subunit LacA -
  NPS18_RS06925 (NPS18_06925) lacR 1422162..1422917 (-) 756 WP_002262461.1 transcriptional regulator LacR -
  NPS18_RS06930 (NPS18_06930) rexA 1423142..1426780 (-) 3639 WP_002262919.1 helicase-exonuclease AddAB subunit AddA Machinery gene
  NPS18_RS06935 (NPS18_06935) rexB 1426770..1430012 (-) 3243 WP_002262920.1 ATP-dependent nuclease subunit B Machinery gene
  NPS18_RS06940 (NPS18_06940) - 1430884..1431129 (-) 246 WP_002262921.1 SemiSWEET family transporter -
  NPS18_RS06945 (NPS18_06945) - 1431304..1431630 (-) 327 WP_002262922.1 hypothetical protein -

Sequence

Protein


Download         Length: 1212 a.a.        Molecular weight: 139291.98 Da        Isoelectric Point: 4.8382

>NTDB_id=613632 NPS18_RS06930 WP_002262919.1 1423142..1426780(-) (rexA) [Streptococcus mutans strain UA-159]
MTFKPFLTDQEIASLQIQEAQSDKKQKRTPEQIEAIYTSGTNILVSASAGSGKTFVMIERIMDKILRGVTIDQLFISTFT
VKAAGELKERLEKKITEQLRLTNDTALKQFLSEQLLGLQTADIGTMDAFTQKLVTQYGYTLGISPNFRILQDKSEQDLLK
NDVFDDLFTDYRTGDQAELFTKLVRNFAGNRKDSSNFRQIIYKIYDFSQATDNPQRWLLENFLKGANTYKDFSAIPEQEV
KDFLNTLQETALALRDVTDLEDYKQVTAKGTPTAAYQRHLKMIEQLQDWVLHFDSLYGRDGLGKLANDIATLIPSGNDVT
VAGVKYPVFRSLHSRLRGLKHLETIFKYQDQSLPLLQVLQSFTLDFSKQYLQAKMQENAFEFSDIAHFAIQILEENDAIR
QLYIDKYHEVMVDEYQDNNHTQERMLELLSNGRNRFMVGDIKQSIYRFRQADPQIFNQKFKDFQEHPEHGKLILLKENFR
SQSEVLDATNSVFTHLMDEAVGEILYDDTHQLVAGSSAQKIPYPQNETQVLIYDTKDQQNQDLAVEDDSNQISLGEVKLV
AKEIIRLHNEEKVQFEDITLLVSSRTRNDGILQTFDDYGIPLVTDGGEQNYLKSVEVMVMLDTLRSIDNPLNDYALVALL
RSPMFAFDEDDLARLALQNLPDQHKQNLYEKMENARNGQGQQVQLITEALSAKLDAFFETFLSWREFSLLNSLYDLIWKI
YNDKFYYDYVGSLPKSEQRQANLYALALRADNFEKTGFKGLSRFIRMIDKILENQNDLADVEVALPKNAVTLMTIHKSKG
LEFKYVFILNIDKKFSIQDMTSPLILSRQNGVGIKYIADMKEELEEKLLPTVKVSMDTLPYQLNKRELRLATLSEQMRLL
YVAMTRSEKKLYLVGKGSQEKLGDQYDGKSENNHLPVADREHYLTFQDWLLAIEAAYAADELHFKTSFITDEDLTEDKMG
SLEAEQAYDADNLKDNRQSDDITRALDMLEAVEKLNQHYKAAIHLPTVRTPSQIKKFYEPVMETEGVEVMQTSYQTKPKF
ELPQFSKKAKQDPTALGSSVHELMQRLHLSEQVSLEDILTALAELSVEENVKKAIQVDKILHFFQTSQLGKLIQANADKV
YREAPFAMLQADPASGEDYVVRGIIDGYILFDNRIVLFDYKTDKFTNSQAIKERYRGQMTLYAQALSQSYNIQQVDSYLI
LLGGEKLEVVEI

Nucleotide


Download         Length: 3639 bp        

>NTDB_id=613632 NPS18_RS06930 WP_002262919.1 1423142..1426780(-) (rexA) [Streptococcus mutans strain UA-159]
ATGACCTTTAAACCATTTTTAACAGATCAAGAAATAGCTTCCTTACAAATTCAAGAAGCTCAGTCTGATAAGAAACAAAA
ACGAACGCCTGAGCAAATTGAGGCTATTTACACTTCAGGAACCAATATTTTGGTTTCTGCCTCTGCTGGTTCAGGAAAAA
CCTTTGTGATGATTGAGCGGATTATGGATAAAATTCTGCGTGGTGTAACGATTGATCAGCTTTTTATTTCCACCTTTACC
GTTAAGGCTGCTGGTGAGCTTAAGGAGCGTTTAGAAAAGAAAATCACCGAGCAATTGCGTTTGACAAATGACACTGCCCT
CAAACAATTTCTCAGCGAACAACTCTTGGGATTGCAGACTGCGGATATTGGAACCATGGATGCCTTTACCCAAAAATTAG
TGACACAGTACGGCTATACCTTGGGAATTTCACCGAATTTTCGAATTTTACAAGATAAAAGCGAGCAGGATCTTCTTAAA
AATGATGTCTTTGACGACCTTTTTACTGATTACAGAACTGGCGATCAAGCAGAGCTTTTCACTAAGCTTGTTAGGAATTT
TGCTGGAAATCGAAAAGATTCGAGCAATTTTAGACAAATCATTTACAAAATTTATGATTTCAGTCAGGCAACCGATAATC
CCCAAAGATGGCTTTTGGAGAATTTCTTAAAGGGAGCCAATACCTATAAGGATTTTTCAGCTATTCCTGAACAAGAAGTG
AAAGACTTTTTGAATACTTTGCAGGAAACTGCTCTCGCTCTTCGTGATGTGACGGATTTAGAAGATTACAAGCAAGTAAC
GGCTAAAGGAACTCCAACAGCAGCTTATCAAAGGCACCTTAAAATGATTGAGCAGCTGCAGGATTGGGTCTTGCATTTTG
ACAGTCTATATGGGCGAGATGGTCTGGGGAAATTAGCAAATGACATTGCAACACTCATTCCATCTGGTAACGATGTGACA
GTAGCAGGAGTTAAATATCCTGTCTTTCGCAGTTTGCACAGTCGCTTAAGAGGACTAAAACACTTGGAAACAATTTTCAA
GTATCAGGATCAAAGTCTGCCTTTGTTGCAAGTACTGCAATCTTTTACACTTGATTTTTCAAAACAATACCTGCAAGCAA
AGATGCAGGAAAATGCCTTTGAGTTTTCAGACATTGCACATTTTGCTATCCAGATTTTAGAAGAAAATGATGCTATTCGT
CAGCTTTATATAGATAAGTATCACGAAGTCATGGTAGATGAATATCAGGATAATAATCACACCCAAGAGCGCATGTTGGA
ACTTTTATCTAATGGGCGCAATCGCTTCATGGTAGGAGATATTAAGCAATCTATCTATCGGTTTCGTCAGGCAGATCCAC
AGATTTTTAATCAAAAATTTAAGGATTTTCAAGAACATCCAGAGCATGGAAAACTCATTCTCTTAAAAGAGAACTTTCGG
AGTCAGTCAGAAGTCTTAGATGCTACCAATAGTGTTTTTACGCATCTTATGGATGAAGCGGTTGGAGAAATTCTCTACGA
TGATACCCATCAGCTTGTGGCTGGCAGTTCAGCTCAGAAAATTCCTTATCCGCAAAATGAAACACAAGTCCTCATCTATG
ATACAAAGGATCAGCAAAATCAAGATCTTGCTGTAGAAGATGATAGTAATCAAATCAGTCTAGGTGAGGTCAAATTGGTT
GCTAAGGAGATTATTCGCCTTCATAATGAAGAAAAGGTTCAGTTTGAAGATATTACCTTGCTTGTCTCATCGCGGACACG
CAATGATGGTATCTTGCAAACATTTGATGATTATGGCATTCCTTTGGTGACTGATGGTGGTGAACAAAATTATCTGAAAT
CAGTGGAAGTTATGGTCATGTTGGATACTCTGCGTTCTATTGATAATCCTCTCAATGATTATGCTCTAGTAGCTCTTTTG
CGTTCACCTATGTTTGCTTTTGATGAGGATGACTTGGCTCGTCTAGCTCTGCAAAATCTACCAGATCAACACAAACAAAA
TCTTTATGAAAAGATGGAGAATGCCAGAAATGGCCAAGGCCAGCAAGTTCAGTTGATCACAGAAGCATTGTCTGCCAAAT
TGGATGCTTTCTTTGAAACTTTCCTCAGTTGGCGTGAGTTTAGTCTCTTAAATTCGCTCTATGATTTGATTTGGAAAATT
TATAATGATAAATTTTACTATGATTATGTGGGAAGTTTACCAAAATCTGAACAGCGCCAAGCCAATCTTTATGCTCTAGC
CCTGCGTGCCGATAACTTTGAGAAAACAGGTTTTAAGGGGTTGTCGCGCTTCATTCGCATGATTGACAAAATTCTAGAAA
ATCAAAATGACTTGGCTGATGTTGAAGTCGCTTTACCTAAAAATGCAGTGACGCTGATGACGATTCATAAGAGTAAGGGA
TTGGAATTTAAATATGTCTTTATTCTTAATATTGATAAAAAATTTAGCATTCAAGATATGACATCACCCTTAATTTTATC
GCGGCAAAACGGTGTTGGTATCAAGTATATTGCTGATATGAAAGAAGAACTAGAGGAAAAATTATTGCCGACAGTTAAAG
TCAGCATGGATACTCTTCCTTATCAACTGAATAAGCGTGAGCTTCGCCTGGCAACCCTATCTGAACAAATGCGATTGCTT
TATGTTGCCATGACACGATCTGAAAAGAAACTTTACTTGGTCGGAAAAGGCAGTCAGGAAAAATTAGGGGATCAGTATGA
TGGCAAATCAGAAAACAATCATTTGCCAGTAGCTGATCGTGAACACTATTTGACTTTTCAGGATTGGCTTTTGGCGATTG
AAGCTGCTTATGCTGCCGATGAACTTCATTTTAAAACAAGTTTTATAACGGATGAAGACTTAACAGAAGATAAAATGGGA
AGTTTAGAAGCAGAGCAGGCTTATGATGCGGATAATCTTAAGGATAATCGGCAATCAGATGATATTACGCGTGCTTTAGA
TATGTTAGAAGCAGTTGAAAAATTAAATCAGCACTATAAGGCTGCTATCCATTTACCAACTGTTCGTACGCCAAGTCAGA
TCAAAAAATTTTATGAGCCTGTTATGGAAACAGAAGGTGTAGAGGTGATGCAAACTTCCTATCAGACTAAACCAAAGTTT
GAGCTGCCTCAATTTTCAAAAAAGGCGAAACAAGATCCAACAGCTCTTGGTTCAAGTGTTCATGAACTTATGCAGCGGCT
TCATTTGAGTGAACAGGTTAGTCTTGAAGATATTTTAACTGCTCTGGCAGAACTATCTGTAGAAGAAAATGTTAAAAAAG
CTATTCAGGTTGATAAGATTTTGCATTTCTTCCAGACCAGCCAACTGGGGAAACTCATTCAAGCAAATGCTGACAAGGTC
TATCGTGAAGCACCCTTTGCTATGCTGCAAGCGGATCCTGCAAGCGGAGAAGACTATGTCGTGCGGGGGATTATTGACGG
TTACATTCTTTTTGATAATCGGATTGTCCTCTTTGATTATAAAACAGATAAATTCACTAATAGTCAAGCTATTAAAGAGC
GTTACCGAGGTCAGATGACACTTTATGCTCAAGCTTTGAGCCAATCCTATAATATCCAACAAGTAGACAGTTATTTAATT
CTATTAGGCGGTGAAAAATTAGAAGTTGTGGAAATTTAA

Domains

Predicted by InterProScan.

UvrD-like helicase C-terminal domain (UvrD_C)

(473-893)

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(1041-1191)

UvrD/REP helicase N-terminal domain (UvrD-helicase)

(29-464)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DT76

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexA Streptococcus pneumoniae R6

52.602

100

0.534