Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   RSAU_RS09995 Genome accession   NC_022222
Coordinates   1998261..1998977 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus subsp. aureus 6850     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1993261..2003977
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RSAU_RS09965 (RSAU_001864) - 1993479..1994105 (+) 627 WP_000522383.1 nitroreductase family protein -
  RSAU_RS09970 (RSAU_001865) - 1994466..1995251 (+) 786 WP_000867953.1 carbon-nitrogen family hydrolase -
  RSAU_RS14995 (RSAU_001868) hld 1995850..1995930 (-) 81 WP_000046023.1 delta-hemolysin -
  RSAU_RS09980 (RSAU_001869) - 1996220..1996783 (+) 564 WP_001105715.1 accessory gene regulator AgrB -
  RSAU_RS09985 (RSAU_001870) agrD 1996785..1996925 (+) 141 WP_001094303.1 cyclic lactone autoinducer peptide AgrD -
  RSAU_RS09990 (RSAU_001871) agrC 1996950..1998242 (+) 1293 WP_020977431.1 quorum-sensing sensor histidine kinase AgrC -
  RSAU_RS09995 (RSAU_001872) agrA 1998261..1998977 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  RSAU_RS10000 - 1999049..1999156 (+) 108 WP_041204320.1 hypothetical protein -
  RSAU_RS10005 (RSAU_001873) - 1999344..2000303 (-) 960 WP_020977432.1 carbohydrate kinase family protein -
  RSAU_RS10010 (RSAU_001874) - 2000300..2001784 (-) 1485 WP_000141418.1 sucrose-6-phosphate hydrolase -
  RSAU_RS10015 (RSAU_001875) - 2001933..2002883 (-) 951 WP_020977433.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=61341 RSAU_RS09995 WP_000688492.1 1998261..1998977(+) (agrA) [Staphylococcus aureus subsp. aureus 6850]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=61341 RSAU_RS09995 WP_000688492.1 1998261..1998977(+) (agrA) [Staphylococcus aureus subsp. aureus 6850]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment