Detailed information NTG0061340

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: RSAU_RS09460
• Genome accession: NC_022222
• Coordinates: 1896448..1897491 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus subsp. aureus 6850
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1891448..1902491

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RSAU_RS09430 (RSAU_001766)	-	1891869..1893125 (-)	1257	WP_078066285.1	aminopeptidase	-
RSAU_RS09435 (RSAU_001767)	-	1893128..1893328 (-)	201	WP_000180460.1	DUF1128 family protein	-
RSAU_RS09440 (RSAU_001768)	-	1893475..1893939 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
RSAU_RS09445 (RSAU_001769)	-	1893946..1894221 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
RSAU_RS09450 (RSAU_001770)	-	1894499..1895716 (+)	1218	WP_000037087.1	YihY/virulence factor BrkB family protein	-
RSAU_RS09455 (RSAU_001771)	vraR	1895829..1896458 (-)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
RSAU_RS09460 (RSAU_001772)	vraS	1896448..1897491 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
RSAU_RS09465 (RSAU_001773)	liaF	1897488..1898189 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
RSAU_RS09470 (RSAU_001774)	-	1898204..1898590 (-)	387	WP_001110179.1	hypothetical protein	-
RSAU_RS09475 (RSAU_001775)	map	1898807..1899565 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
RSAU_RS09480 (RSAU_001776)	-	1900035..1901021 (+)	987	WP_000999715.1	FUSC family protein	-
RSAU_RS09485 (RSAU_001777)	-	1901210..1901623 (-)	414	WP_020977397.1	hypothetical protein	-
RSAU_RS09490	-	1901652..1901762 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=61340 RSAU_RS09460 WP_001017131.1 1896448..1897491(-) (vraS) [Staphylococcus aureus subsp. aureus 6850]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=61340 RSAU_RS09460 WP_001017131.1 1896448..1897491(-) (vraS) [Staphylococcus aureus subsp. aureus 6850]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1