Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   NP444_RS22225 Genome accession   NZ_CP101911
Coordinates   4789190..4790404 (-) Length   404 a.a.
NCBI ID   WP_003112721.1    Uniprot ID   Q9I5N8
Organism   Pseudomonas aeruginosa strain NWRC-1223     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4784190..4795404
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NP444_RS22215 (NP444_22215) - 4786372..4787484 (-) 1113 WP_003112720.1 substrate-binding domain-containing protein -
  NP444_RS22220 (NP444_22220) lapA 4787570..4788676 (-) 1107 WP_003455131.1 alkaline phosphatase LapA -
  NP444_RS22225 (NP444_22225) pilC 4789190..4790404 (-) 1215 WP_003112721.1 type II secretion system inner membrane protein GspF Machinery gene
  NP444_RS22230 (NP444_22230) pilB 4790404..4791813 (-) 1410 WP_003120811.1 type II secretion system ATPase GspE Machinery gene
  NP444_RS22235 (NP444_22235) gspD 4791810..4794221 (-) 2412 WP_014603262.1 type II secretion system secretin GspD -
  NP444_RS22240 (NP444_22240) - 4794218..4794811 (-) 594 WP_003141147.1 type II secretion system protein M -

Sequence

Protein


Download         Length: 404 a.a.        Molecular weight: 43409.42 Da        Isoelectric Point: 9.3769

>NTDB_id=612255 NP444_RS22225 WP_003112721.1 4789190..4790404(-) (pilC) [Pseudomonas aeruginosa strain NWRC-1223]
MQTFRYEAADAQGRIETGTLEADSQRGALGQLRARGLTPLEVREQAGGGTGQGAGALFAPRLSDGDLAWATRQLASLLAA
SLPLEAALSATLDQAERKHIAQTLSAVRSDVRGGMRLADALAARPRDFPEIYRALVAAGEESGDLAQVMERLADYIEERN
ALRGKILTAFIYPAVVGVVSIGIVIFLLGYVVPQVVSAFSQARQDLPALTRAMLQASDFVRAWGWLCAGAIGSAYWGWRL
YLRDPQARLGWHRRVLRLPLLGRFVLGVNTARFASTLAILGSAGVPLLRALDAARQTLANDCLAQAVEEATAQVREGVSL
ASALRTRQVFPPILTHLIASGEKTGALPPMLDRAAQTLSRDIERRAMGMTALLEPLMIVVMGGVVLTIVMAVLMPIIEMN
QLVQ

Nucleotide


Download         Length: 1215 bp        

>NTDB_id=612255 NP444_RS22225 WP_003112721.1 4789190..4790404(-) (pilC) [Pseudomonas aeruginosa strain NWRC-1223]
ATGCAGACCTTCCGTTACGAAGCCGCCGACGCCCAGGGCCGGATCGAGACCGGCACCCTGGAGGCGGACAGCCAGCGTGG
CGCCCTCGGCCAACTGCGCGCCCGCGGCCTGACCCCGCTGGAGGTCCGCGAGCAGGCTGGCGGCGGGACCGGGCAAGGGG
CGGGCGCGCTGTTCGCCCCGCGCCTGTCCGACGGCGACCTGGCCTGGGCCACCCGCCAGCTGGCCAGCCTGCTGGCCGCC
AGCCTGCCGCTGGAGGCGGCGCTGAGCGCCACCCTCGACCAGGCCGAGCGCAAGCACATCGCCCAGACCCTGAGCGCCGT
GCGCAGCGACGTGCGCGGCGGCATGCGCCTGGCCGACGCCCTTGCCGCACGGCCGCGGGACTTCCCGGAAATCTACCGGG
CGCTGGTGGCTGCGGGCGAGGAGTCCGGCGACCTGGCCCAGGTGATGGAGCGCCTGGCCGACTACATCGAGGAACGCAAC
GCCCTGCGCGGCAAGATCCTCACCGCGTTCATCTACCCGGCGGTGGTCGGCGTGGTCTCCATCGGCATCGTCATTTTCCT
CCTCGGCTACGTGGTGCCGCAGGTGGTCAGCGCCTTCTCCCAGGCGCGCCAGGACCTGCCGGCGCTGACCCGGGCGATGC
TCCAGGCCAGCGACTTCGTGCGCGCCTGGGGCTGGCTCTGCGCCGGCGCCATCGGTAGCGCTTACTGGGGCTGGCGCTTG
TACCTGCGCGACCCGCAGGCGCGGCTCGGCTGGCACCGGCGAGTGCTGCGCCTGCCTCTGCTCGGTCGCTTCGTGCTCGG
GGTGAACACCGCGCGCTTCGCCTCCACCCTGGCGATCCTCGGCAGCGCCGGCGTACCGCTGCTGCGCGCGCTCGATGCGG
CGCGCCAGACGTTGGCCAACGACTGCCTCGCGCAGGCGGTGGAGGAGGCCACCGCGCAGGTTCGCGAAGGTGTCTCGCTG
GCCTCGGCGCTGCGCACGCGGCAGGTGTTCCCGCCGATCCTCACCCACCTGATCGCCAGCGGCGAGAAGACCGGTGCGCT
GCCGCCGATGCTCGACCGCGCGGCGCAGACCCTGTCGCGCGACATCGAGCGCCGCGCCATGGGCATGACCGCGTTGCTCG
AGCCGCTGATGATCGTGGTCATGGGCGGGGTGGTGCTGACCATCGTGATGGCGGTGCTGATGCCGATCATCGAGATGAAC
CAACTGGTCCAGTAG

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(273-395)

Type II secretion system (T2SS), protein F (T2SSF)

(71-193)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9I5N8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Thermus thermophilus HB27

36.386

100

0.364