Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   NOO62_RS22760 Genome accession   NZ_CP101750
Coordinates   4995696..4996820 (-) Length   374 a.a.
NCBI ID   WP_150170668.1    Uniprot ID   A0A5P2BWR8
Organism   Streptomyces sp. Je 1-369     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4990696..5001820
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NOO62_RS22740 (NOO62_22755) - 4991460..4993118 (+) 1659 WP_268772738.1 sensor histidine kinase -
  NOO62_RS22745 (NOO62_22760) - 4993115..4993816 (+) 702 WP_268772739.1 response regulator transcription factor -
  NOO62_RS22750 (NOO62_22765) - 4993875..4994630 (-) 756 WP_268772740.1 phosphatase PAP2 family protein -
  NOO62_RS22755 (NOO62_22770) - 4994804..4995628 (+) 825 WP_268772741.1 hypothetical protein -
  NOO62_RS22760 (NOO62_22775) disA 4995696..4996820 (-) 1125 WP_150170668.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  NOO62_RS22765 (NOO62_22780) radA/sms 4996899..4998308 (-) 1410 WP_268772742.1 DNA repair protein RadA Machinery gene
  NOO62_RS22770 (NOO62_22785) - 4998517..5000397 (+) 1881 WP_268772743.1 BACON domain-containing protein -
  NOO62_RS22775 (NOO62_22790) - 5000432..5001412 (-) 981 WP_414930868.1 hypothetical protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40291.21 Da        Isoelectric Point: 4.9269

>NTDB_id=611809 NOO62_RS22760 WP_150170668.1 4995696..4996820(-) (disA) [Streptomyces sp. Je 1-369]
MAANDRASVPGKPGSGSGADGLMRASLSAVAPGMALRDGLERILRGNTGGLIVLGWDKTVESMCTGGFILDVEFTATRLR
ELCKLDGGIVLDKDITKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALAELDSLTHAELLELPTVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=611809 NOO62_RS22760 WP_150170668.1 4995696..4996820(-) (disA) [Streptomyces sp. Je 1-369]
GTGGCAGCCAACGACCGGGCATCGGTTCCCGGCAAGCCGGGTTCGGGCTCCGGTGCCGATGGGCTGATGCGCGCCTCCCT
GAGCGCCGTCGCGCCCGGGATGGCACTGCGGGACGGCCTGGAACGCATCCTCCGCGGCAACACGGGTGGCCTGATCGTCC
TCGGCTGGGACAAGACCGTCGAGTCGATGTGTACGGGCGGTTTCATCCTGGACGTCGAGTTCACGGCGACGCGGCTGCGT
GAGCTGTGCAAGCTCGACGGCGGCATCGTCCTCGACAAGGACATCACCAAAATCCTGCGCGCGGGCGTGCAGCTCGTGCC
GGATCCGACGATTCCCACGGAGGAGACGGGCACACGGCACCGCACGGCGGACCGCGTGAGCAAGCAGGTCGGCTTCCCCG
TCGTCTCCGTCTCCCAGTCCATGCGACTGATCGCGCTGTACGTGGACGGCCAGCGGCGCGTCCTGGAGGACTCGGCGGCG
ATCCTCTCCCGCGCGAACCAGGCGCTCGCCACCCTTGAGCGGTACAAGCTCCGTCTCGACGAGGTCGCGGGCACGCTGTC
GGCTCTGGAGATCGAGGACCTGGTGACGGTGCGGGACGTCACCGCCGTCGCGCAGCGCCTCGAAATGGTGCGCCGCATCG
CGACGGAGATCGCCGAGTACGTGGTGGAGCTCGGCACGGACGGGCGTCTCCTCGCCCTCCAGCTGGACGAGTTGATCGCG
GGCGTCGAGCCCGAGCGCGAGCTGGTCGTGCGGGACTACGTGCCCGAGCCCACGGCCAAGCGGTCCCGCACGGTCGACGA
GGCGCTGGCCGAGCTGGACTCCCTCACCCACGCGGAGCTCCTCGAACTCCCCACGGTGGCGCGGGCCCTGGGTTACACGG
GCTCCCCCGAGGCGCTGGACTCCGCGGTGTCCCCGCGGGGCTTCCGTCTCCTCGCCAAGGTCCCCCGGCTCCCCGGAGCG
ATCATCGACCGCCTGGTCGAGCACTTCGGCGGCCTGCAGAAGCTCCTCGCCGCCAGCGTGGACGACCTCCAGACGGTGGA
CGGCGTCGGCGAGGCCCGGGCGAGGAGCGTCCGCGAGGGCCTGTCGCGCCTGGCGGAATCGTCGATCCTGGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)

Helix-hairpin-helix motif (HHH_2)

(324-359)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5P2BWR8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

44.598

96.524

0.43