Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   LE167_RS08510 Genome accession   NZ_CP084443
Coordinates   1756763..1757479 (+) Length   238 a.a.
NCBI ID   WP_002461418.1    Uniprot ID   -
Organism   Staphylococcus lugdunensis strain RMLUG5     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1751763..1762479
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LE167_RS08485 (LE167_08510) - 1752556..1753179 (+) 624 WP_002461413.1 nitroreductase family protein -
  LE167_RS08490 (LE167_08515) - 1753314..1754099 (+) 786 WP_002477923.1 carbon-nitrogen family hydrolase -
  LE167_RS08495 (LE167_08520) - 1754727..1755293 (+) 567 WP_070817133.1 accessory gene regulator AgrB -
  LE167_RS08500 (LE167_08525) agrD 1755296..1755439 (+) 144 WP_002477921.1 cyclic lactone autoinducer peptide AgrD -
  LE167_RS08505 (LE167_08530) agrC 1755461..1756750 (+) 1290 WP_002477920.1 quorum-sensing sensor histidine kinase AgrC -
  LE167_RS08510 (LE167_08535) agrA 1756763..1757479 (+) 717 WP_002461418.1 quorum-sensing response regulator AgrA Regulator
  LE167_RS08515 (LE167_08540) - 1757571..1758545 (-) 975 WP_002477919.1 carbohydrate kinase family protein -
  LE167_RS08520 (LE167_08545) - 1758546..1760030 (-) 1485 WP_002477918.1 sucrose-6-phosphate hydrolase -
  LE167_RS08525 (LE167_08550) - 1760130..1761080 (-) 951 WP_002461422.1 LacI family DNA-binding transcriptional regulator -
  LE167_RS08530 (LE167_08555) - 1761180..1762424 (-) 1245 WP_002477917.1 ammonium transporter -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27935.92 Da        Isoelectric Point: 5.9140

>NTDB_id=611356 LE167_RS08510 WP_002461418.1 1756763..1757479(+) (agrA) [Staphylococcus lugdunensis strain RMLUG5]
MKIYICEDDVKQRENMVEIINNYIMIEEKPMEIALATDNPYEILKMSKENEDVGCYFLDIQLEADINGIKLGSEIRKYDP
IGNIIFVTSHSELTYLTFVYKVSAMDFIFKDDPAELKTRIIDCLETAHTRLKLLSKERTVETIELKRGSNSVYVQYDEVM
FFESSTNSHRLIAHLDNRQIEFYGNLKQISQIDDRFFRCHNSFVVNRHNISSINSKERVVYFKNGEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=611356 LE167_RS08510 WP_002461418.1 1756763..1757479(+) (agrA) [Staphylococcus lugdunensis strain RMLUG5]
ATGAAGATTTACATTTGTGAAGATGATGTTAAACAACGTGAAAATATGGTTGAGATCATCAATAACTATATCATGATTGA
AGAAAAACCAATGGAAATTGCTTTAGCTACAGATAATCCTTATGAAATTTTAAAAATGTCAAAGGAAAATGAGGATGTTG
GTTGTTATTTTTTAGATATTCAATTAGAAGCTGACATAAACGGTATCAAGTTAGGTAGCGAAATAAGAAAGTATGATCCG
ATAGGTAACATAATTTTTGTTACAAGTCATAGTGAGCTGACATATTTAACTTTTGTTTACAAAGTATCGGCTATGGATTT
TATTTTTAAAGATGACCCTGCCGAACTTAAAACTCGTATTATCGATTGCCTTGAAACCGCACATACGCGCTTAAAGTTAT
TGTCAAAAGAACGTACCGTTGAAACGATAGAGCTTAAGCGCGGTAGTAATTCTGTATATGTGCAATATGATGAAGTGATG
TTTTTTGAATCATCAACAAATTCACATCGATTGATTGCACATTTAGATAATCGTCAAATTGAGTTTTATGGTAATCTAAA
ACAAATTAGTCAAATCGATGATCGTTTCTTTAGATGCCATAATAGTTTTGTTGTCAATCGACACAATATCTCTTCAATCA
ATTCAAAAGAACGTGTTGTATATTTTAAAAATGGTGAACATTGTTATGCATCAGTACGCAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

86.555

100

0.866