Detailed information NTG0610850

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: LA387_RS06230
• Genome accession: NZ_CP084377
• Coordinates: 1220318..1222768 (-)
• Length: 816 a.a.
• NCBI ID: WP_003134008.1
• Uniprot ID: -
• Organism: Lactococcus garvieae strain Lg-Granada
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1215318..1227768

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LA387_RS06220	pflB	1217056..1219389 (-)	2334	WP_003134012.1	formate C-acetyltransferase	-
LA387_RS06225	hpf	1219637..1220194 (-)	558	WP_003134010.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
LA387_RS06230	clpC	1220318..1222768 (-)	2451	WP_003134008.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
LA387_RS06235	-	1222758..1223210 (-)	453	WP_003134006.1	CtsR family transcriptional regulator	-
LA387_RS06240	greA	1223332..1223805 (-)	474	WP_003134005.1	transcription elongation factor GreA	-
LA387_RS06245	mltG	1223830..1225545 (-)	1716	WP_003134003.1	endolytic transglycosylase MltG	-
LA387_RS06250	rpoE	1225651..1226211 (-)	561	WP_003134001.1	DNA-directed RNA polymerase subunit delta	-
LA387_RS06255	-	1226349..1226861 (-)	513	WP_003134000.1	adenine phosphoribosyltransferase	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 91136.42 Da
• Isoelectric Point: 6.2962

>NTDB_id=610850 LA387_RS06230 WP_003134008.1 1220318..1222768(-) (clpC) [Lactococcus garvieae strain Lg-Granada]
MKFNEKDFTPQVVRVLEKSVDYAHKFNYAWVESSHLLAALAEVPASLAFTLLNSEKIDLEEMLIDIEDFSSQMKTKKSEI
KLSPRVETIIEQARALAQNNDKNRIGTEHLLYMLLANEASFAGQLLREQNINIVNLRKKLEQKAYLRVPERRKAVTPASK
RNLSGKVSETTTTPTLDTVSTDLTKAAREGKLDPMIGREREVERLIHILSRRTKNNPVLVGEPGVGKSAIIEGFATRVAA
GNVPVGLRGSRIMALNMAMVVAGTKFRGEFEDRLTAIVNEVTHDKDVIVFIDELHTIIGAGGGMDSVNDASNILKPALAR
GEFQLIGATTYQEYQKYIEKDEALERRFARVNVEEPSEKETVAILQGLKEKFEAYHAVKFEEGALERAVSLSNRYMPSRR
LPDKAIDLLDEAAAKVKITSKTNYTKLDELKAELKAEELKLQQAVVALDIVEAQGIEKDIERLTHKIDNFTVSENDNPLV
EESDIYAVVSNLTGIPLQQMTKTESERLINLEKELHKRVVGQEEAISAVSRAIRRARSGIADTRRPLGSFMFLGPTGVGK
TELAKALAESVFGSEENMIRVDMSEFMEKFSTSRLIGAPPGYVGYDEGGQLTEQVRNKPYSVILLDEVEKAHPDIFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATAIRDDKTVGFGAKSISTDYAAMKARIMEELKKQYRPEFLNRIDETIVF
HSLTEKEIEQVVKIMSKSLVSRLKDQNITVKFTPAALKVIADKGFDPEYGARPLRKALQREVEDTLSEQLLAGDIHPGDT
ISIGSSNKKIRISVID

Nucleotide

• Length: 2451 bp

>NTDB_id=610850 LA387_RS06230 WP_003134008.1 1220318..1222768(-) (clpC) [Lactococcus garvieae strain Lg-Granada]
ATGAAATTTAATGAAAAGGACTTTACACCACAAGTTGTTAGAGTGCTCGAGAAGTCTGTCGACTATGCGCATAAGTTTAA
CTACGCTTGGGTAGAAAGCTCGCACCTATTGGCTGCCTTGGCTGAGGTTCCGGCTTCATTGGCATTTACGCTACTTAATT
CAGAAAAGATTGATTTGGAAGAGATGTTAATCGACATCGAAGATTTTTCAAGTCAAATGAAGACAAAAAAATCAGAAATA
AAGCTTAGCCCAAGAGTCGAAACGATTATTGAGCAAGCCCGAGCATTGGCTCAAAATAACGATAAAAACCGTATTGGGAC
AGAACATCTCTTGTATATGCTGTTGGCAAATGAAGCCAGCTTTGCAGGACAACTTTTACGTGAGCAAAACATTAATATCG
TTAACCTCCGTAAAAAGTTAGAGCAAAAAGCATATTTACGAGTGCCAGAACGCCGTAAAGCGGTGACCCCAGCCTCAAAA
AGAAACCTGTCGGGGAAGGTGTCCGAAACAACAACAACACCTACTTTAGATACAGTCTCGACAGATTTGACAAAAGCAGC
GCGTGAAGGAAAGCTTGATCCAATGATTGGGAGAGAGCGTGAAGTCGAACGTCTTATCCATATTTTGAGTCGCCGAACAA
AGAATAATCCCGTTCTTGTTGGTGAACCAGGCGTTGGTAAGTCAGCGATTATTGAAGGCTTTGCAACACGTGTGGCTGCA
GGGAATGTTCCTGTAGGTTTACGCGGCAGTCGTATCATGGCCTTGAATATGGCGATGGTCGTAGCGGGGACGAAGTTCCG
TGGCGAATTTGAAGATCGTTTGACAGCTATTGTGAATGAAGTGACACATGATAAAGATGTTATCGTCTTTATCGATGAAC
TCCATACTATTATTGGTGCTGGGGGAGGCATGGACTCTGTCAATGATGCCTCAAACATTTTAAAACCCGCATTAGCACGT
GGCGAGTTTCAACTTATTGGTGCTACTACTTATCAAGAATATCAAAAATATATTGAAAAAGATGAAGCTCTGGAGCGTCG
TTTTGCCCGTGTCAATGTCGAAGAACCCTCAGAAAAAGAAACGGTTGCGATTTTACAAGGCTTGAAAGAAAAATTTGAAG
CTTACCATGCGGTTAAATTTGAAGAGGGGGCTTTGGAGCGTGCCGTTAGCTTGAGTAATCGCTACATGCCAAGTCGTCGT
CTGCCAGACAAAGCCATTGATCTTCTTGATGAAGCAGCGGCCAAAGTTAAAATCACGAGTAAAACAAATTACACCAAGCT
AGACGAGTTAAAAGCAGAATTAAAAGCGGAAGAGCTGAAATTACAACAAGCAGTTGTTGCTCTTGATATTGTTGAAGCAC
AAGGAATTGAAAAAGATATTGAAAGATTAACACACAAAATTGATAATTTTACAGTATCGGAAAATGATAATCCTTTGGTC
GAAGAAAGCGATATTTATGCTGTTGTTTCTAACCTTACAGGAATTCCGCTCCAACAAATGACGAAAACAGAAAGTGAACG
TCTGATTAACTTAGAAAAAGAGTTACATAAACGTGTGGTCGGACAGGAAGAAGCGATTTCGGCTGTTTCTCGTGCTATAA
GACGTGCGCGTTCAGGTATTGCTGATACGAGACGTCCTCTGGGCTCATTTATGTTCCTTGGTCCGACAGGGGTTGGGAAA
ACAGAGCTTGCTAAAGCTTTAGCGGAAAGTGTCTTTGGGAGTGAAGAGAACATGATTCGCGTAGACATGAGTGAATTTAT
GGAAAAATTCTCGACATCGCGTCTTATCGGAGCACCTCCAGGGTATGTAGGTTACGACGAAGGGGGACAATTGACAGAGC
AAGTCCGTAATAAGCCTTATTCTGTTATTCTCCTTGATGAAGTTGAAAAAGCCCATCCTGACATTTTCAATATCATGTTG
CAAATTTTGGATGACGGTTTCGTTACAGATACCAAAGGGCGGAAGGTTGATTTCCGAAATACAATCATTATTATGACATC
CAACTTAGGCGCAACGGCTATTCGTGATGATAAAACGGTTGGTTTTGGGGCTAAATCAATTTCAACAGATTATGCAGCCA
TGAAAGCAAGAATCATGGAAGAGCTGAAGAAACAGTACCGTCCAGAATTTCTTAATCGTATCGATGAAACCATCGTTTTC
CATTCACTGACAGAAAAAGAGATTGAACAAGTCGTGAAAATCATGAGTAAATCTCTTGTATCACGTTTGAAAGATCAAAA
TATTACAGTGAAATTTACCCCTGCTGCCTTGAAAGTTATTGCTGATAAAGGATTTGATCCTGAGTATGGTGCACGTCCGT
TGCGTAAAGCGCTACAACGGGAGGTTGAAGACACGCTCAGTGAGCAATTGCTTGCAGGCGACATTCATCCGGGGGATACG
ATTTCGATTGGGTCTTCTAATAAAAAGATTAGAATAAGTGTTATTGATTGA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (357-445)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (22-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-349)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	70.552	99.877	0.705
clpC	Streptococcus thermophilus LMD-9	49.698	100	0.504
clpC	Streptococcus thermophilus LMG 18311	49.698	100	0.504
clpC	Streptococcus pneumoniae TIGR4	49.516	100	0.501
clpC	Streptococcus pneumoniae D39	49.395	100	0.5
clpC	Streptococcus pneumoniae Rx1	49.395	100	0.5
clpC	Streptococcus mutans UA159	47.488	100	0.487
clpC	Bacillus subtilis subsp. subtilis str. 168	48.185	97.917	0.472
clpE	Streptococcus mutans UA159	46.875	78.431	0.368