Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   M493_RS03805 Genome accession   NC_022080
Coordinates   736110..737933 (+) Length   607 a.a.
NCBI ID   WP_020958957.1    Uniprot ID   S5ZLD1
Organism   Geobacillus genomosp. 3     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 731110..742933
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M493_RS03785 (M493_04195) - 731389..732051 (-) 663 WP_020958953.1 TerC family protein -
  M493_RS03790 (M493_04200) mecA 732267..732947 (+) 681 WP_020958954.1 adaptor protein MecA -
  M493_RS03795 (M493_04205) cls 733109..734617 (+) 1509 WP_020958955.1 cardiolipin synthase -
  M493_RS03800 (M493_04210) - 734788..736077 (+) 1290 WP_020958956.1 competence protein CoiA -
  M493_RS03805 (M493_04215) pepF 736110..737933 (+) 1824 WP_020958957.1 oligoendopeptidase F Regulator
  M493_RS03810 (M493_04220) - 737947..738144 (-) 198 WP_020958958.1 hypothetical protein -
  M493_RS03815 (M493_04225) spxH 738430..739323 (-) 894 WP_020958959.1 ClpXP adapter protein SpxH -
  M493_RS03820 (M493_04230) - 739316..739729 (-) 414 WP_020958960.1 globin -
  M493_RS03825 (M493_04235) - 739831..740442 (-) 612 WP_020958961.1 lytic transglycosylase domain-containing protein -
  M493_RS03830 (M493_04240) - 740439..741029 (-) 591 WP_020958962.1 CYTH domain-containing protein -
  M493_RS03835 (M493_04245) - 741159..741536 (+) 378 WP_020958963.1 hypothetical protein -
  M493_RS03840 (M493_04250) - 741642..742280 (+) 639 WP_020958964.1 GTP pyrophosphokinase -

Sequence

Protein


Download         Length: 607 a.a.        Molecular weight: 70214.09 Da        Isoelectric Point: 5.1387

>NTDB_id=61043 M493_RS03805 WP_020958957.1 736110..737933(+) (pepF) [Geobacillus genomosp. 3]
MTVEENKAKKSLPSRSDIPVEETWRLEDIFPTDDAWEQEFQQVKGMIPKLSEYKGRLSESPEVMYEALQYQDEVSMRLGK
LYTYAHMRYDQDTTNSFYQGLNDRAKGLYSEASSAMAFIVPEILAIDEAVLRSFLEQYEPLRLYTHALDEITRQRPHILS
AEEEALLAQAAEVMQATSSTFSALNNADLIFPTIRDENGEEVEVTHGRFIRFLESTDRRVRRDAFRAVYHTYEKFQNTFA
NTLAGTVKKDNFFARVRRYSSAREAALDANNIPESVYDNLIATIHEHLPLLHRYVRLRKNVLGLDELHMYDLYTPLVQDV
KMEVTYDEAKQYMLDGLAPLGEEYVAIVKEGLDNRWVDVRENKGKRSGAYSSGAYGTHPYILLNWQDNVNNLFTLVHEFG
HSVHSYYTRKTQPYPYAHYSIFVAEVASTCNEALLNDHLLKTIDDEKKRLYLLNHYLEGFRGTVFRQTMFAEFEHLIHQK
AQEGEALTAKTLTSLYYDLNKKYFGDDMVVDEEIGLEWARIPHFYYNYYVYQYATGFSAATALSRQILEEGEPAVKRYID
FLKAGSSDYPIEVLKKAGVDMTSAEPIRQACQVFAEKLAEMERLLGK

Nucleotide


Download         Length: 1824 bp        

>NTDB_id=61043 M493_RS03805 WP_020958957.1 736110..737933(+) (pepF) [Geobacillus genomosp. 3]
ATGACGGTGGAAGAGAATAAGGCAAAGAAGTCGCTCCCGTCCCGGAGCGACATACCTGTCGAGGAAACGTGGCGGCTCGA
GGACATTTTCCCGACCGATGACGCTTGGGAACAGGAGTTTCAGCAAGTGAAAGGGATGATCCCGAAGCTCAGCGAATACA
AAGGCCGGCTTAGCGAATCGCCGGAAGTGATGTATGAAGCGCTGCAATACCAAGATGAAGTGTCGATGCGCCTTGGGAAG
CTGTATACATACGCCCATATGCGCTATGACCAAGATACGACGAACTCGTTTTACCAAGGGCTCAACGACCGGGCAAAAGG
GTTGTATAGCGAAGCGTCGAGCGCGATGGCGTTTATCGTTCCAGAAATTTTAGCCATTGACGAAGCGGTGTTGCGTTCAT
TTTTGGAGCAATACGAACCGCTCCGCCTGTATACGCATGCGTTAGATGAAATCACGCGCCAACGCCCGCACATTTTGTCA
GCTGAAGAAGAAGCGCTATTGGCGCAGGCCGCCGAGGTCATGCAGGCGACGTCATCGACATTCAGCGCGTTAAACAACGC
TGACCTCATCTTTCCGACGATCCGTGACGAAAACGGGGAAGAGGTGGAAGTGACGCACGGCCGGTTTATCCGCTTTTTAG
AAAGCACCGACCGCCGCGTTCGCCGTGATGCGTTTCGCGCCGTGTACCATACGTACGAGAAGTTCCAGAATACGTTTGCC
AACACGCTTGCGGGCACAGTGAAAAAAGATAACTTTTTCGCCCGCGTCCGTCGCTACAGCTCAGCGCGGGAAGCGGCGTT
AGATGCGAACAATATTCCTGAGAGCGTCTATGACAATTTGATCGCCACGATTCACGAGCATTTGCCGCTTTTGCACCGGT
ATGTGCGGCTGCGTAAAAACGTGCTTGGGCTTGACGAGCTGCATATGTACGACTTATATACTCCGCTTGTGCAAGATGTA
AAAATGGAAGTGACATACGACGAAGCGAAGCAATATATGCTTGACGGGCTGGCGCCGCTTGGCGAGGAATATGTGGCGAT
CGTCAAGGAAGGGCTTGACAATCGCTGGGTCGATGTACGCGAAAATAAAGGGAAACGAAGTGGAGCCTACTCGTCGGGGG
CGTATGGCACCCATCCGTACATTTTGCTTAACTGGCAAGACAACGTAAACAACTTGTTTACGCTCGTACATGAGTTCGGC
CACTCGGTCCATAGCTATTATACGCGTAAAACACAGCCGTATCCGTACGCCCACTATTCGATTTTTGTTGCTGAAGTGGC
GTCGACATGCAATGAGGCCTTATTGAACGATCATTTGCTGAAAACGATCGACGATGAGAAAAAACGGCTATACTTGCTGA
ACCATTACCTTGAAGGGTTCCGCGGCACCGTTTTTCGGCAAACGATGTTTGCCGAGTTTGAGCATTTGATTCATCAGAAA
GCGCAGGAGGGAGAAGCGCTGACAGCCAAGACGCTCACATCGCTCTATTATGATCTAAACAAAAAATATTTCGGCGATGA
CATGGTAGTAGATGAGGAAATTGGCCTCGAGTGGGCGCGTATCCCACATTTTTATTACAACTATTACGTGTACCAATACG
CAACCGGCTTCAGCGCGGCAACGGCGCTCAGCAGGCAGATTTTGGAGGAAGGAGAACCGGCGGTGAAACGGTACATCGAC
TTTTTAAAAGCCGGCAGCTCGGATTACCCGATCGAAGTGTTGAAAAAAGCCGGCGTCGATATGACGAGCGCTGAGCCGAT
CCGCCAAGCGTGCCAAGTGTTTGCGGAGAAGTTGGCGGAAATGGAGCGCCTGCTTGGAAAATAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(122-191)

Peptidase family M3 (Peptidase_M3)

(213-592)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S5ZLD1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

50.673

97.858

0.496

Multiple sequence alignment