Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   NMK57_RS24750 Genome accession   NZ_CP101305
Coordinates   4935831..4938653 (+) Length   940 a.a.
NCBI ID   WP_000357734.1    Uniprot ID   -
Organism   Escherichia coli strain 2002-3211     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4930831..4943653
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMK57_RS24725 (NMK57_24725) soxR 4931768..4932232 (-) 465 WP_000412428.1 redox-sensitive transcriptional activator SoxR -
  NMK57_RS24730 (NMK57_24730) soxS 4932318..4932641 (+) 324 WP_000019358.1 superoxide response transcriptional regulator SoxS -
  NMK57_RS24735 (NMK57_24735) pdeC 4932644..4934230 (-) 1587 WP_000019543.1 c-di-GMP phosphodiesterase PdeC -
  NMK57_RS24740 (NMK57_24740) yjcB 4934660..4934941 (+) 282 WP_001295689.1 YjcB family protein -
  NMK57_RS24745 (NMK57_24745) ssb 4935040..4935576 (-) 537 WP_000168305.1 single-stranded DNA-binding protein SSB1 Machinery gene
  NMK57_RS24750 (NMK57_24750) uvrA 4935831..4938653 (+) 2823 WP_000357734.1 excinuclease ABC subunit UvrA Machinery gene
  NMK57_RS24755 (NMK57_24755) yjbR 4938688..4939044 (-) 357 WP_000155657.1 MmcQ/YjbR family DNA-binding protein -
  NMK57_RS24760 (NMK57_24760) yjbQ 4939048..4939464 (-) 417 WP_000270372.1 secondary thiamine-phosphate synthase enzyme YjbQ -
  NMK57_RS24765 (NMK57_24765) aphA 4939575..4940288 (-) 714 WP_001307512.1 acid phosphatase AphA -
  NMK57_RS24770 (NMK57_24770) - 4940690..4940912 (+) 223 Protein_4881 hypothetical protein -
  NMK57_RS24775 (NMK57_24775) tyrB 4941415..4942608 (-) 1194 WP_000486966.1 aromatic amino acid transaminase -

Sequence

Protein


Download         Length: 940 a.a.        Molecular weight: 103905.54 Da        Isoelectric Point: 6.6066

>NTDB_id=610307 NMK57_RS24750 WP_000357734.1 4935831..4938653(+) (uvrA) [Escherichia coli strain 2002-3211]
MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS
PAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLAESFETALELSGGTAVVADMDDP
KAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQM
LKSLADHYKFDVEAPWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSAVREELAKF
ISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAGQRAKIAEKILKEIGDRLKFLVNVGLNYLTL
SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRDFGNTVIVVEHDEDAIRAADHVIDI
GPGAGVHGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLKDVTLTLPVGLFTCITG
VSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPE
SRARGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEAREFF
DAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLDVLHKLRD
QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECEASHTARFLKTML

Nucleotide


Download         Length: 2823 bp        

>NTDB_id=610307 NMK57_RS24750 WP_000357734.1 4935831..4938653(+) (uvrA) [Escherichia coli strain 2002-3211]
ATGGATAAGATCGAAGTTCGGGGCGCCCGCACCCATAATCTCAAAAACATCAACCTCGTTATCCCCCGCGACAAGCTCAT
TGTCGTGACCGGGCTTTCGGGTTCTGGCAAATCCTCGCTCGCTTTCGACACCTTATATGCCGAAGGGCAGCGCCGTTACG
TTGAATCCCTTTCCGCCTACGCGCGGCAGTTTCTGTCACTGATGGAAAAGCCGGACGTCGATCATATTGAGGGGCTTTCT
CCTGCCATCTCAATTGAGCAGAAATCGACGTCTCATAACCCGCGTTCTACGGTGGGGACAATCACCGAAATCCACGACTA
TTTACGTTTGTTGTTCGCCCGCGTTGGCGAACCGCGCTGTCCGGACCACGACGTCCCGCTGGCGGCGCAAACCGTCAGCC
AGATGGTGGATAACGTGCTGTCGCAGCCGGAAGGCAAGCGTCTGATGCTGCTCGCGCCAATCATTAAAGAGCGCAAAGGC
GAACACACCAAAACACTGGAGAACCTGGCAAGCCAGGGCTACATCCGTGCTCGTATTGATGGCGAAGTCTGCGATCTTTC
CGATCCGCCGAAACTGGAACTGCAAAAGAAACACACTATTGAAGTGGTGGTTGATCGCTTCAAGGTGCGTGACGATCTTA
CCCAACGTCTTGCCGAGTCGTTTGAAACCGCGCTGGAGCTTTCCGGTGGTACCGCGGTAGTGGCGGATATGGACGACCCG
AAAGCGGAAGAGCTGCTGTTCTCTGCCAACTTCGCCTGCCCAATTTGCGGCTACAGTATGCGTGAACTGGAGCCGCGACT
GTTTTCGTTTAACAACCCGGCAGGTGCCTGCCCGACCTGTGACGGCCTTGGCGTACAGCAATATTTCGATCCTGACCGCG
TGATCCAAAACCCCGAGCTATCGCTGGCTGGCGGTGCGATCCGTGGCTGGGATCGCCGCAACTTCTATTATTTCCAGATG
CTGAAATCGCTGGCAGATCACTATAAGTTCGACGTCGAAGCGCCGTGGGGCAGCCTGAGCGCGAACGTGCATAAAGTGGT
GTTGTACGGTTCTGGCAAAGAAAACATTGAATTCAAATACATGAACGATCGTGGCGATACCTCCATTCGTCGTCATCCGT
TCGAAGGCGTGCTGCACAATATGGAGCGCCGTTATAAAGAGACGGAATCCAGTGCGGTACGTGAAGAATTAGCCAAGTTT
ATCAGTAATCGTCCGTGCGCCAGCTGCGAAGGAACCCGTCTGCGTCGGGAAGCGCGCCACGTTTATGTCGAGAATACGCC
GCTGCCTGCTATCTCCGACATGAGCATCGGTCATGCGATGGAATTCTTCAACAATCTCAAACTCGCTGGTCAACGGGCGA
AGATTGCGGAAAAAATCCTTAAAGAGATCGGCGATCGCCTGAAATTCCTCGTTAACGTCGGTCTGAATTACCTGACACTT
TCCCGCTCGGCAGAGACACTTTCCGGCGGTGAAGCCCAGCGTATTCGTCTGGCGAGCCAGATTGGTGCGGGCCTGGTTGG
CGTTATGTACGTGCTGGACGAGCCGTCTATCGGCCTGCACCAGCGCGATAACGAGCGCCTGTTGGGTACGCTTATCCATC
TGCGCGATTTCGGTAATACCGTGATTGTGGTGGAGCACGACGAAGACGCGATTCGCGCGGCTGACCATGTGATCGATATC
GGTCCTGGTGCGGGTGTTCACGGCGGTGAAGTGGTCGCGGAAGGTCCACTGGAAGCGATTATGGCGGTGCCGGAGTCGTT
AACCGGACAGTACATGAGCGGTAAACGCAAGATTGAAGTGCCGAAGAAACGCGTTCCGGCAAATCCGGAAAAAGTGCTGA
AGCTGACAGGCGCACGCGGCAACAACCTGAAGGACGTGACGCTCACGCTGCCAGTCGGTCTGTTTACCTGCATCACAGGG
GTTTCAGGTTCCGGTAAATCGACGCTGATTAACGACACACTGTTCCCGATTGCCCAACGCCAGTTGAATGGTGCGACCAT
CGCCGAACCGGCACCGTATCGCGATATTCAGGGGCTGGAGCATTTCGATAAAGTGATCGATATCGACCAAAGCCCAATTG
GTCGTACTCCACGTTCTAACCCGGCGACCTATACCGGCGTGTTTACACCTGTGCGCGAACTGTTTGCGGGCGTACCGGAA
TCCCGTGCGCGTGGTTATACGCCAGGACGTTTCAGCTTTAACGTCCGTGGCGGGCGCTGCGAAGCCTGTCAGGGCGACGG
TGTGATCAAAGTGGAGATGCACTTCCTGCCGGATATCTACGTGCCGTGCGATCAGTGCAAAGGTAAACGCTATAACCGTG
AAACGCTGGAAATTAAGTACAAAGGCAAAACCATCCACGAAGTGCTGGATATGACCATCGAAGAGGCGCGTGAGTTCTTT
GATGCCGTACCGGCTCTAGCGCGAAAGCTGCAAACGTTGATGGACGTTGGCCTGACGTATATTCGCCTGGGGCAATCCGC
CACCACGCTTTCTGGCGGTGAAGCCCAGCGCGTGAAGCTGGCGCGTGAGCTGTCAAAACGCGGCACCGGGCAGACGCTGT
ATATTCTCGACGAGCCGACCACCGGTCTGCACTTCGCCGATATTCAGCAACTGCTCGACGTACTGCATAAACTGCGCGAT
CAGGGCAATACCATTGTGGTAATTGAGCACAATCTCGACGTGATTAAAACCGCTGACTGGATTGTCGACCTGGGACCAGA
AGGCGGCAGTGGCGGCGGCGAGATCCTTGTCTCCGGTACGCCAGAAACCGTCGCGGAGTGCGAAGCATCACACACGGCAC
GTTTCCTCAAGACGATGCTGTAA

Domains

Predicted by InterProScan.

UvrA DNA-binding domain (UvrA_DNA-bind)

(290-399)

ABC transporter (ABC_tran)

(806-860)

UvrA interaction domain (UvrA_inter)

(130-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

57.264

100

0.574
  uvrA Streptococcus pneumoniae TIGR4

57.264

100

0.574
  uvrA Streptococcus pneumoniae D39

57.264

100

0.574