Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   RES5_RS04190 Genome accession   NZ_CP084235
Coordinates   856271..856987 (-) Length   238 a.a.
NCBI ID   WP_011275301.1    Uniprot ID   Q4L7S3
Organism   Staphylococcus haemolyticus strain SE2.14     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 851271..861987
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RES5_RS04170 (RES5_004170) - 851311..852555 (+) 1245 WP_161511002.1 ammonium transporter -
  RES5_RS04175 (RES5_004175) - 852656..853615 (+) 960 WP_085060369.1 LacI family DNA-binding transcriptional regulator -
  RES5_RS04180 (RES5_004180) - 853700..855184 (+) 1485 WP_037551256.1 sucrose-6-phosphate hydrolase -
  RES5_RS04185 (RES5_004185) - 855188..856153 (+) 966 WP_161511001.1 carbohydrate kinase -
  RES5_RS04190 (RES5_004190) agrA 856271..856987 (-) 717 WP_011275301.1 quorum-sensing response regulator AgrA Regulator
  RES5_RS04195 (RES5_004195) agrC 857006..858289 (-) 1284 WP_161511000.1 quorum-sensing sensor histidine kinase AgrC -
  RES5_RS04200 (RES5_004200) agrD 858316..858456 (-) 141 WP_053017473.1 cyclic lactone autoinducer peptide AgrD -
  RES5_RS04205 (RES5_004205) - 858459..859025 (-) 567 WP_161510999.1 accessory gene regulator AgrB -
  RES5_RS04210 (RES5_004210) - 859755..860540 (-) 786 WP_037551247.1 carbon-nitrogen family hydrolase -
  RES5_RS04215 (RES5_004215) - 860735..861358 (-) 624 WP_161510998.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27801.74 Da        Isoelectric Point: 5.2189

>NTDB_id=610223 RES5_RS04190 WP_011275301.1 856271..856987(-) (agrA) [Staphylococcus haemolyticus strain SE2.14]
MKIFICEDDVKQRENMVSIINNYIMIEEKPMEIALATDDPYEVIEKSKEMNDVGCYFLDIQLEADINGIKLGSEIRKYDP
IGNIIFVTSHSELTYLTFVYKVSAMDFIFKDDPSQLQSRIIDCLETAHTRLKLLSKESTVETIELKRGSNSIYVQYDDVM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVVNRHNIESIDSKERIVNFKNGEHCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=610223 RES5_RS04190 WP_011275301.1 856271..856987(-) (agrA) [Staphylococcus haemolyticus strain SE2.14]
ATGAAAATATTCATTTGTGAAGATGATGTAAAACAACGCGAAAATATGGTTTCAATTATTAATAATTACATTATGATTGA
AGAAAAACCTATGGAGATTGCGCTTGCAACAGACGATCCTTATGAAGTCATTGAAAAATCTAAAGAGATGAATGATGTCG
GATGTTACTTTCTAGATATTCAATTAGAGGCTGATATCAACGGTATTAAATTAGGTAGTGAAATTCGTAAGTATGACCCT
ATTGGAAATATCATATTCGTTACAAGTCATAGTGAGTTAACGTACCTAACCTTTGTTTACAAAGTGTCAGCAATGGATTT
TATCTTTAAAGATGATCCAAGCCAATTACAGTCCAGAATTATTGATTGCTTAGAAACTGCACACACTCGCTTAAAATTAT
TATCTAAAGAAAGTACTGTTGAAACGATTGAATTGAAACGAGGAAGTAATTCAATTTATGTTCAATATGATGACGTAATG
TTTTTCGAATCATCTACAAAATCACATCGATTAATCGCACATTTAGATAATCGTCAAATTGAGTTCTATGGCAATTTAAA
AGAACTTGCACAACTTGATGAGCGGTTCTTTAGATGTCACAACAGCTTCGTTGTTAACAGACATAATATTGAATCCATAG
ATTCAAAAGAACGTATTGTCAATTTTAAAAACGGTGAGCACTGTTTTGCTTCGGTTCGTAATGTTAAAAAAATATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4L7S3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878