Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   RES6_RS04175 Genome accession   NZ_CP084229
Coordinates   856276..856992 (-) Length   238 a.a.
NCBI ID   WP_011275301.1    Uniprot ID   Q4L7S3
Organism   Staphylococcus haemolyticus strain SE3.8     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 851276..861992
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RES6_RS04155 (RES6_004155) - 851316..852560 (+) 1245 WP_161511002.1 ammonium transporter -
  RES6_RS04160 (RES6_004160) - 852661..853620 (+) 960 WP_085060369.1 LacI family DNA-binding transcriptional regulator -
  RES6_RS04165 (RES6_004165) - 853705..855189 (+) 1485 WP_037551256.1 sucrose-6-phosphate hydrolase -
  RES6_RS04170 (RES6_004170) - 855193..856158 (+) 966 WP_161511001.1 carbohydrate kinase -
  RES6_RS04175 (RES6_004175) agrA 856276..856992 (-) 717 WP_011275301.1 quorum-sensing response regulator AgrA Regulator
  RES6_RS04180 (RES6_004180) agrC 857011..858294 (-) 1284 WP_161511000.1 quorum-sensing sensor histidine kinase AgrC -
  RES6_RS04185 (RES6_004185) agrD 858321..858461 (-) 141 WP_053017473.1 cyclic lactone autoinducer peptide AgrD -
  RES6_RS04190 (RES6_004190) - 858464..859030 (-) 567 WP_161510999.1 accessory gene regulator AgrB -
  RES6_RS04195 (RES6_004195) - 859760..860545 (-) 786 WP_037551247.1 carbon-nitrogen family hydrolase -
  RES6_RS04200 (RES6_004200) - 860740..861363 (-) 624 WP_161510998.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27801.74 Da        Isoelectric Point: 5.2189

>NTDB_id=610190 RES6_RS04175 WP_011275301.1 856276..856992(-) (agrA) [Staphylococcus haemolyticus strain SE3.8]
MKIFICEDDVKQRENMVSIINNYIMIEEKPMEIALATDDPYEVIEKSKEMNDVGCYFLDIQLEADINGIKLGSEIRKYDP
IGNIIFVTSHSELTYLTFVYKVSAMDFIFKDDPSQLQSRIIDCLETAHTRLKLLSKESTVETIELKRGSNSIYVQYDDVM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVVNRHNIESIDSKERIVNFKNGEHCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=610190 RES6_RS04175 WP_011275301.1 856276..856992(-) (agrA) [Staphylococcus haemolyticus strain SE3.8]
ATGAAAATATTCATTTGTGAAGATGATGTAAAACAACGCGAAAATATGGTTTCAATTATTAATAATTACATTATGATTGA
AGAAAAACCTATGGAGATTGCGCTTGCAACAGACGATCCTTATGAAGTCATTGAAAAATCTAAAGAGATGAATGATGTCG
GATGTTACTTTCTAGATATTCAATTAGAGGCTGATATCAACGGTATTAAATTAGGTAGTGAAATTCGTAAGTATGACCCT
ATTGGAAATATCATATTCGTTACAAGTCATAGTGAGTTAACGTACCTAACCTTTGTTTACAAAGTGTCAGCAATGGATTT
TATCTTTAAAGATGATCCAAGCCAATTACAGTCCAGAATTATTGATTGCTTAGAAACTGCACACACTCGCTTAAAATTAT
TATCTAAAGAAAGTACTGTTGAAACGATTGAATTGAAACGAGGAAGTAATTCAATTTATGTTCAATATGATGACGTAATG
TTTTTCGAATCATCTACAAAATCACATCGATTAATCGCACATTTAGATAATCGTCAAATTGAGTTCTATGGCAATTTAAA
AGAACTTGCACAACTTGATGAGCGGTTCTTTAGATGTCACAACAGCTTCGTTGTTAACAGACATAATATTGAATCCATAG
ATTCAAAAGAACGTATTGTCAATTTTAAAAACGGTGAGCACTGTTTTGCTTCGGTTCGTAATGTTAAAAAAATATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4L7S3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878