Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   NMT99_RS16965 Genome accession   NZ_CP101290
Coordinates   3256861..3258237 (-) Length   458 a.a.
NCBI ID   WP_029725912.1    Uniprot ID   -
Organism   Bacillus subtilis strain LjM2     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3251861..3263237
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMT99_RS16940 feuV 3251898..3252725 (-) 828 WP_010886609.1 ABC transporter ATP-binding protein -
  NMT99_RS16945 cotNW 3252943..3253380 (-) 438 WP_029725909.1 YusW family protein -
  NMT99_RS16950 - 3253490..3255286 (-) 1797 WP_029725910.1 M3 family oligoendopeptidase -
  NMT99_RS16955 yusZ 3255421..3256267 (+) 847 Protein_3283 oxidoreductase -
  NMT99_RS16960 mrgA 3256357..3256818 (+) 462 WP_015714679.1 metalloregulation DNA-binding stress protein MgrA -
  NMT99_RS16965 htrA 3256861..3258237 (-) 1377 WP_029725912.1 serine protease Do-like protein HtrB Regulator
  NMT99_RS16970 cssR 3258515..3259192 (+) 678 WP_003228529.1 secretion stress-responsive two-component system response regulator CssR -
  NMT99_RS16975 cssS 3259189..3260544 (+) 1356 WP_003228527.1 secretion stress-responsive two-component system sensor histidine kinase CssS -
  NMT99_RS16980 spxO 3260572..3260736 (-) 165 WP_003221681.1 anti-adapter protein SpxO -
  NMT99_RS16985 spxN 3260904..3261779 (+) 876 WP_003243192.1 TetR/AcrR family transcriptional regulator -
  NMT99_RS16990 fumC 3261819..3263207 (-) 1389 WP_003228523.1 class II fumarate hydratase -

Sequence

Protein


Download         Length: 458 a.a.        Molecular weight: 48747.21 Da        Isoelectric Point: 4.5582

>NTDB_id=610053 NMT99_RS16965 WP_029725912.1 3256861..3258237(-) (htrA) [Bacillus subtilis strain LjM2]
MDYRRDGQNDQHQTEPSHTEQQNTENQKLIGHSEQELLDAPVSYEAGRQETASALEMEKQETAVKKEKKRRAAWLSPILG
GIIGGGLMLGIAPYLPSDQNQTTETASANKQVQSDNFTTAPITNASNIADMVEDLEPTIVGISNIQTSQNNTFGTGGGSS
SESESGTGSGVIFKKDSDKAYIITNNHVVEGANKLTVTLYNGETETAKLVGSDTITDLAVLEISGKNVKKVASFGDSSQL
RTGEKVIAIGNPLGQQFSGTVTQGIISGLNRTIDVDTTQGTVEMNVLQTDAAINPGNSGGPLINASGQVIGINSLKVSES
GVESLGFAIPSNDVEPIVDQLLQNGKVDRPFLGVQMIDMSQVPETYQENTLGLFGDQLGKGVYVKEVQANSPAEKAGIKS
EDVIVKLNGKDVESSADIRQILYKDLKVGDKTTIQVLRKGKTKTLNATLTKQTESSSS

Nucleotide


Download         Length: 1377 bp        

>NTDB_id=610053 NMT99_RS16965 WP_029725912.1 3256861..3258237(-) (htrA) [Bacillus subtilis strain LjM2]
TTGGATTATCGACGTGATGGCCAAAACGATCAACATCAAACTGAACCTTCACATACAGAACAGCAGAATACAGAAAACCA
GAAGCTGATTGGACATTCTGAACAAGAATTGCTTGACGCGCCTGTGTCGTATGAAGCGGGACGGCAGGAAACGGCTTCTG
CTTTAGAAATGGAAAAGCAAGAAACGGCTGTGAAAAAAGAAAAGAAACGGAGAGCCGCATGGCTGAGCCCGATTTTAGGC
GGTATTATCGGCGGGGGCCTCATGCTTGGCATCGCGCCTTATCTGCCGTCAGACCAAAATCAGACGACCGAGACCGCTTC
CGCAAATAAACAGGTGCAGTCTGATAATTTTACAACGGCGCCGATAACGAACGCATCAAACATCGCTGATATGGTAGAGG
ATTTAGAGCCTACGATTGTCGGAATCTCAAATATCCAAACCTCTCAAAATAACACATTCGGCACGGGAGGAGGCTCCAGC
TCAGAAAGTGAAAGCGGAACCGGTTCAGGTGTCATTTTCAAAAAAGACAGCGATAAAGCGTATATCATTACAAACAACCA
TGTCGTTGAAGGCGCGAACAAGCTGACTGTTACGCTATACAACGGAGAAACGGAAACTGCCAAGCTTGTCGGCAGCGATA
CCATTACTGATTTGGCAGTTTTGGAAATCAGCGGCAAGAACGTCAAAAAAGTGGCGAGCTTTGGTGATTCTTCGCAGCTG
CGCACTGGCGAAAAGGTAATCGCTATCGGTAACCCGCTCGGACAGCAGTTTTCCGGTACGGTGACACAAGGCATCATTAG
CGGACTGAACCGGACAATTGATGTGGATACAACACAAGGGACGGTGGAAATGAACGTGCTGCAAACCGATGCAGCGATCA
ATCCGGGGAACAGCGGAGGCCCATTAATCAATGCAAGCGGCCAGGTCATCGGCATCAACAGCTTGAAGGTGAGCGAAAGC
GGCGTGGAATCACTTGGATTTGCGATCCCAAGCAATGATGTCGAGCCAATTGTTGACCAGCTGCTGCAAAACGGGAAGGT
GGACCGTCCGTTTTTAGGCGTGCAGATGATTGACATGTCACAAGTTCCTGAAACCTATCAGGAAAATACGCTCGGCCTGT
TTGGAGATCAATTGGGCAAAGGTGTTTATGTAAAAGAAGTTCAAGCAAATTCGCCGGCAGAAAAAGCAGGTATTAAATCT
GAGGATGTCATTGTCAAACTAAACGGTAAAGACGTGGAAAGCAGTGCGGATATCCGTCAGATCCTTTACAAAGACTTAAA
AGTCGGAGATAAAACAACAATCCAAGTGCTGCGAAAGGGAAAAACGAAAACGTTGAACGCGACACTGACCAAGCAGACAG
AAAGCAGTTCAAGCTAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(350-449)

Trypsin-like peptidase domain (Trypsin_2)

(168-312)

Peptidase family M50 (Peptidase_M50)

(282-455)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

41.353

87.118

0.36