Detailed information NTG0609941

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: I6G24_RS06930
• Genome accession: NZ_CP084189
• Coordinates: 1349017..1351467 (-)
• Length: 816 a.a.
• NCBI ID: WP_023163844.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain FDAARGOS_867
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1344017..1356467

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6G24_RS06905 (I6G24_06910)	-	1344396..1344965 (+)	570	WP_010905492.1	TetR/AcrR family transcriptional regulator	-
I6G24_RS06910 (I6G24_06915)	-	1344977..1346050 (+)	1074	WP_003129569.1	ABC transporter permease	-
I6G24_RS06915 (I6G24_06920)	-	1346053..1346724 (+)	672	WP_010905491.1	ABC transporter ATP-binding protein	-
I6G24_RS06920 (I6G24_06925)	eno	1346839..1348140 (-)	1302	WP_010905473.1	surface-displayed alpha-enolase	-
I6G24_RS06925 (I6G24_06930)	hpf	1348325..1348882 (-)	558	WP_023163845.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
I6G24_RS06930 (I6G24_06935)	clpC	1349017..1351467 (-)	2451	WP_023163844.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
I6G24_RS06935 (I6G24_06940)	-	1351457..1351912 (-)	456	WP_010905471.1	CtsR family transcriptional regulator	-
I6G24_RS06940 (I6G24_06945)	greA	1352089..1352562 (-)	474	WP_025016857.1	transcription elongation factor GreA	-
I6G24_RS06945 (I6G24_06950)	mltG	1352622..1354274 (-)	1653	WP_010905469.1	endolytic transglycosylase MltG	-
I6G24_RS06950 (I6G24_06955)	rpoE	1354411..1354974 (-)	564	WP_003129551.1	DNA-directed RNA polymerase subunit delta	-
I6G24_RS06955 (I6G24_06960)	-	1355190..1355702 (-)	513	WP_012897343.1	adenine phosphoribosyltransferase	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90391.81 Da
• Isoelectric Point: 6.5300

>NTDB_id=609941 I6G24_RS06930 WP_023163844.1 1349017..1351467(-) (clpC) [Lactococcus lactis strain FDAARGOS_867]
MKFENIKYTPTLDRILEKAEEYAHQYQYGTIESAHLLAAMATTSGSIAYSLLAGMNVDSSDLLIDLEDLSSHVKVKRSTL
RFSPRAEEVMTAASFLAIHNNSEAVGTEHLLYALLQVEDGLGLQLLKLQKINIVSLRKELEKRTGLKVPESKKAVTPMSK
RKMAKGVAENSTTPTLDSVSSDLTEEARLGKLDPMIGREAEIDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSSDPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEAIAILQGLREKFEDYHQVKFTDQAIKSAVMLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQQTKRLDLEKELAEAQEELSEAVIKLDIKASRTKEKAVEKIADKIYKFSVKEDKRQEV
TDQAVVAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHPDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMKSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAVKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
VSIGASNKKIKIAQIV

Nucleotide

• Length: 2451 bp

>NTDB_id=609941 I6G24_RS06930 WP_023163844.1 1349017..1351467(-) (clpC) [Lactococcus lactis strain FDAARGOS_867]
ATGAAATTTGAAAATATAAAATATACACCAACGCTTGACCGAATTTTAGAAAAAGCGGAAGAGTATGCTCACCAATATCA
ATATGGCACCATTGAAAGTGCTCATTTACTGGCTGCAATGGCAACGACCTCAGGTTCAATTGCATACAGCCTCCTTGCTG
GAATGAATGTTGATTCTTCTGACTTACTGATTGATTTAGAGGATTTATCAAGTCATGTTAAGGTCAAACGTTCAACTTTA
CGTTTTTCACCTCGTGCAGAAGAAGTGATGACTGCGGCAAGTTTTTTAGCAATTCATAATAACTCAGAAGCCGTTGGAAC
AGAACACTTGCTTTATGCCCTACTTCAAGTAGAAGATGGATTGGGTCTTCAACTTCTGAAATTACAAAAAATCAATATTG
TATCTTTGCGAAAAGAGCTTGAGAAAAGAACTGGACTCAAAGTTCCAGAAAGTAAAAAAGCTGTGACTCCAATGTCAAAA
CGCAAGATGGCAAAGGGAGTTGCAGAAAATTCAACGACGCCAACGTTAGACTCTGTATCCTCAGATTTAACCGAAGAAGC
TCGCTTGGGTAAACTTGACCCAATGATTGGACGAGAAGCTGAAATTGACCGTTTGATTCATATTCTCAGCCGCAGAACAA
AAAATAATCCTGTCTTAGTTGGAGAGCCCGGTGTTGGGAAATCAGCAATTATTGAAGGTTTGGCCCAAAGAATTGTCAAT
GGTCAAGTTCCAATTGGTTTGATGAATAGTCGAATTATGGCTTTGAATATGGCGACTGTTGTTGCTGGGACAAAATTTAG
AGGTGAATTTGAGGATCGTTTGACAGCTATTGTTGAAGAAGTTAGCAGTGATCCAGATGTCATTATTTTCATTGATGAAT
TACACACAATCATCGGTGCTGGTGGCGGAATGGATTCTGTCAATGATGCCGCAAATATTTTGAAACCAGCGCTTGCTCGT
GGTGATTTTCAAATGGTCGGAGCAACAACCTATCATGAATATCAAAAATATATTGAAAAAGATGAAGCTTTAGAACGCCG
TTTGGCGAGAATAAATGTTGACGAGCCAAGTCCAGATGAAGCGATTGCTATTTTGCAAGGCTTACGTGAAAAATTTGAAG
ACTATCATCAAGTGAAATTTACTGACCAAGCCATTAAAAGTGCTGTAATGCTCAGTGTTCGTTATATGACTAGCCGAAAA
TTGCCTGACAAAGCCATTGATTTACTTGATGAAGCTGCAGCAGCAGTGAAAATTTCTGTCAAAAATCAACAAACAAAACG
TCTTGATTTAGAAAAAGAATTAGCGGAAGCTCAAGAAGAATTATCAGAAGCTGTCATTAAACTTGATATCAAAGCGTCTC
GTACAAAAGAAAAAGCAGTTGAAAAAATTGCTGACAAGATTTATAAATTCTCAGTAAAAGAAGATAAACGTCAAGAAGTT
ACTGACCAAGCTGTTGTTGCTGTTGCCTCAACACTGACAGGTGTTCCAATCACACAAATGACTAAGTCTGAAAGTGATCG
TTTAATCAATCTTGAAAAAGAATTACATAAACGAGTTGTTGGACAAGAAGAAGCTATTTCTGCCGTTTCAAGAGCCATTC
GTCGGGCACGTTCCGGTGTTGCTGACAGCCGTCGTCCAATGGGTTCTTTCATGTTCCTTGGACCAACAGGGGTCGGTAAA
ACCGAACTTGCTAAAGCACTGGCTGACAGTGTGTTTGGTAGTGAAGATAATATGATTCGTGTTGACATGAGTGAATTCAT
GGAAAAACATTCGACTTCACGCTTGATTGGAGCTCCTCCAGGGTATGTAGGTTATGATGAGGGTGGTCAATTGACAGAAC
GCGTTCGTAATAAACCTTATTCTGTTGTTCTTTTAGATGAAGTCGAAAAAGCTCATCCTGACGTTTTCAACATCATGTTG
CAAATTCTAGATGATGGCTTTGTGACTGATACTAAAGGTCGTAAAGTTGATTTCAGAAATACAATTATTATCATGACTTC
AAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACAGTTGGTTTTGGCGCTAAAAATATCACAGCTGATTATTCAGCCA
TGAAATCAAGAATATTAGAAGAGCTTAAACGTCATTATCGTCCTGAGTTTCTTAATCGAATTGATGAAAATATTGTTTTC
CACTCATTGGAAAGTCAAGAGATTGAACAAATTGTTAAAATTATGAGTAAATCTTTGATTAAACGTCTGGCAGAACAAGA
TATTCATGTTAAACTCACACCGTCAGCGGTGAAATTAATTGCTGAGGTAGGTTTTGACCCAGAATATGGTGCACGTCCGC
TCCGCAAGGCTCTTCAAAAAGAAGTTGAAGACCTTTTAAGTGAACAATTGCTCTCTGGTGAAATCAAAGCAGGTAATCAT
GTTTCAATTGGGGCATCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-802)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-334)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (19-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-144)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• AAA lid domain (AAA_lid_9) (357-453)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	99.877	100	0.999
clpC	Streptococcus thermophilus LMD-9	50.542	100	0.515
clpC	Streptococcus thermophilus LMG 18311	50.421	100	0.513
clpC	Streptococcus pneumoniae D39	48.918	100	0.499
clpC	Streptococcus pneumoniae Rx1	48.918	100	0.499
clpC	Streptococcus pneumoniae TIGR4	48.798	100	0.498
clpC	Bacillus subtilis subsp. subtilis str. 168	50.499	98.284	0.496
clpC	Streptococcus mutans UA159	48.558	100	0.495
clpE	Streptococcus mutans UA159	47.846	79.657	0.381
clpC	Lactococcus lactis subsp. cremoris KW2	47.023	80.27	0.377
clpE	Streptococcus pneumoniae TIGR4	47.687	76.838	0.366
clpE	Streptococcus pneumoniae Rx1	47.687	76.838	0.366
clpE	Streptococcus pneumoniae D39	47.687	76.838	0.366
clpE	Streptococcus pneumoniae R6	47.687	76.838	0.366