Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   EL277_RS05780 Genome accession   NZ_AP018936
Coordinates   1101287..1101751 (-) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain NU83127     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1096287..1106751
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL277_RS05760 (SPNU_1093) - 1097238..1098206 (-) 969 WP_000105360.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  EL277_RS05765 (SPNU_1094) pdrM 1098360..1099721 (-) 1362 WP_000278524.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  EL277_RS05770 (SPNU_1095) - 1099732..1099992 (-) 261 WP_001105925.1 hypothetical protein -
  EL277_RS05775 (SPNU_1096) - 1100006..1101274 (-) 1269 WP_000924508.1 dihydroorotase -
  EL277_RS05780 (SPNU_1097) mutX 1101287..1101751 (-) 465 WP_001135768.1 NUDIX hydrolase Machinery gene
  EL277_RS05785 (SPNU_1098) - 1101761..1102414 (-) 654 WP_000401326.1 uracil-DNA glycosylase -
  EL277_RS05790 (SPNU_1099) - 1102552..1103154 (-) 603 WP_001812270.1 hypothetical protein -
  EL277_RS05795 (SPNU_1100) - 1103212..1103925 (-) 714 WP_000499429.1 YjjG family noncanonical pyrimidine nucleotidase -
  EL277_RS05800 (SPNU_1101) dhaM 1104385..1104759 (-) 375 WP_000443795.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  EL277_RS12720 - 1104759..1104833 (-) 75 Protein_1105 dihydroxyacetone kinase subunit L -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=60984 EL277_RS05780 WP_001135768.1 1101287..1101751(-) (mutX) [Streptococcus pneumoniae strain NU83127]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=60984 EL277_RS05780 WP_001135768.1 1101287..1101751(-) (mutX) [Streptococcus pneumoniae strain NU83127]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987

Multiple sequence alignment