Detailed information    

insolico Bioinformatically predicted

Overview

Name   cytR   Type   Regulator
Locus tag   NML19_RS22665 Genome accession   NZ_CP101263
Coordinates   4666819..4667811 (-) Length   330 a.a.
NCBI ID   WP_000224470.1    Uniprot ID   P0ACQ1
Organism   Escherichia coli strain EC21Z-063     
Function   promote competence gene expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 4661819..4672811
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NML19_RS22655 (NML19_22650) yieP 4664711..4665403 (+) 693 WP_001131164.1 FadR/GntR family transcriptional regulator -
  NML19_RS22660 (NML19_22655) mdtD 4665426..4666853 (+) 1428 WP_001280852.1 multidrug transporter subunit MdtD -
  NML19_RS22665 (NML19_22660) cytR 4666819..4667811 (-) 993 WP_000224470.1 ribose operon transcriptional repressor RbsR Regulator
  NML19_RS22670 (NML19_22665) rbsK 4667815..4668744 (-) 930 WP_001300603.1 ribokinase -
  NML19_RS22675 (NML19_22670) rbsB 4668870..4669760 (-) 891 WP_001056273.1 ribose ABC transporter substrate-binding protein RbsB -
  NML19_RS22680 (NML19_22675) rbsC 4669785..4670750 (-) 966 WP_000211858.1 ribose ABC transporter permease -
  NML19_RS22685 (NML19_22680) rbsA 4670755..4672260 (-) 1506 WP_000387770.1 ribose ABC transporter ATP-binding protein RbsA -
  NML19_RS22690 (NML19_22685) rbsD 4672268..4672687 (-) 420 WP_001301979.1 D-ribose pyranase -

Sequence

Protein


Download         Length: 330 a.a.        Molecular weight: 36611.90 Da        Isoelectric Point: 5.2141

>NTDB_id=609772 NML19_RS22665 WP_000224470.1 4666819..4667811(-) (cytR) [Escherichia coli strain EC21Z-063]
MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELNYAPSALARSLKLNQTHTIGMLITASTNPFYSELVRG
VERSCFERGYSLVLCNTEGDEQRMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTGDFEFNGGFDAMRQLLSHPLRPQ
AVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDIELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQL
TPILMERGSA

Nucleotide


Download         Length: 993 bp        

>NTDB_id=609772 NML19_RS22665 WP_000224470.1 4666819..4667811(-) (cytR) [Escherichia coli strain EC21Z-063]
TTGGCTACAATGAAAGATGTTGCCCGCCTGGCGGGCGTTTCTACCTCAACAGTTTCTCACGTTATCAATAAAGATCGCTT
CGTCAGTGAAGCGATTACCGCCAAAGTTGAAGCGGCGATTAAAGAACTCAATTACGCGCCATCAGCTCTGGCGCGTAGCC
TCAAACTCAATCAAACACATACCATTGGCATGTTGATCACTGCCAGTACCAATCCTTTCTATTCAGAACTGGTGCGTGGC
GTTGAACGCAGCTGCTTCGAACGCGGTTATAGTCTCGTCCTTTGCAATACCGAAGGCGATGAACAGCGGATGAATCGCAA
TCTGGAAACGCTGATGCAAAAACGCGTTGATGGCTTGCTGTTACTGTGCACCGAAACGCATCAACCTTCGCGTGAAATCA
TGCAACGTTATCCGACAGTGCCTACTGTGATGATGGACTGGGCTCCGTTCGATGGCGACAGCGATCTTATTCAGGATAAC
TCGTTGCTGGGCGGAGACTTAGCAACGCAATATCTGATCGATAAAGGTCATACCCGTATCGCCTGTATTACCGGCCCGCT
GGATAAAACTCCGGCGCGCCTGCGGTTGGAAGGTTATCGGGCGGCGATGAAACGTGCGGGTCTCAACATTCCTGATGGCT
ATGAAGTCACTGGTGATTTTGAATTTAACGGCGGGTTTGACGCTATGCGCCAACTGCTATCACATCCGCTGCGTCCTCAG
GCCGTCTTTACCGGAAATGACGCTATGGCTGTTGGCGTTTACCAGGCGTTATATCAGGCAGAGTTACAGGTTCCGCAGGA
TATCGCGGTGATTGGCTATGACGATATCGAACTGGCAAGCTTTATGACGCCACCATTAACCACTATCCACCAACCGAAAG
ATGAACTGGGGGAGCTGGCGATTGATGTACTCATCCATCGGATAACCCAGCCGACCCTTCAGCAACAACGATTACAACTT
ACTCCGATTCTGATGGAACGCGGTTCGGCTTAG

Domains

Predicted by InterProScan.

Periplasmic binding protein-like domain (Peripla_BP_3)

(169-329)

Bacterial regulatory proteins, lacI family (LacI)

(3-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0ACQ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cytR Vibrio parahaemolyticus RIMD 2210633

37.048

100

0.373
  cytR Vibrio cholerae C6706

39.088

93.03

0.364