Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   LB316_RS10110 Genome accession   NZ_CP084107
Coordinates   2051998..2052714 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain CC49/ST49-MSSA     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2046998..2057714
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LB316_RS10080 (LB316_10075) - 2047231..2047857 (+) 627 WP_000522389.1 nitroreductase family protein -
  LB316_RS10085 (LB316_10080) - 2048219..2049004 (+) 786 WP_000867953.1 carbon-nitrogen family hydrolase -
  LB316_RS10090 (LB316_10085) hld 2049586..2049666 (-) 81 WP_000046022.1 delta-hemolysin -
  LB316_RS10095 (LB316_10090) - 2049957..2050520 (+) 564 WP_001105698.1 accessory gene regulator ArgB-like protein -
  LB316_RS10100 (LB316_10095) - 2050523..2050666 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide -
  LB316_RS10105 (LB316_10100) - 2050696..2051979 (+) 1284 WP_000447894.1 sensor histidine kinase -
  LB316_RS10110 (LB316_10105) agrA 2051998..2052714 (+) 717 WP_000688492.1 LytTR family DNA-binding domain-containing protein Regulator
  LB316_RS10115 (LB316_10110) - 2052786..2052893 (+) 108 WP_031927342.1 hypothetical protein -
  LB316_RS10120 (LB316_10115) - 2053081..2054040 (-) 960 WP_001253297.1 carbohydrate kinase -
  LB316_RS10125 (LB316_10120) - 2054037..2055521 (-) 1485 WP_000141418.1 glycoside hydrolase family 32 protein -
  LB316_RS10130 (LB316_10125) - 2055670..2056620 (-) 951 WP_000790320.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=609593 LB316_RS10110 WP_000688492.1 2051998..2052714(+) (agrA) [Staphylococcus aureus strain CC49/ST49-MSSA]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=609593 LB316_RS10110 WP_000688492.1 2051998..2052714(+) (agrA) [Staphylococcus aureus strain CC49/ST49-MSSA]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACTTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAACATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1