Detailed information    

insolico Bioinformatically predicted

Overview

Name   cytR   Type   Regulator
Locus tag   NML23_RS22440 Genome accession   NZ_CP101240
Coordinates   4622952..4623944 (-) Length   330 a.a.
NCBI ID   WP_000224476.1    Uniprot ID   A7ZTW4
Organism   Escherichia coli strain EC21Z-101     
Function   promote competence gene expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 4617952..4628944
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NML23_RS22430 (NML23_22430) yieP 4620844..4621536 (+) 693 WP_001131169.1 FadR/GntR family transcriptional regulator -
  NML23_RS22435 (NML23_22435) mdtD 4621559..4622986 (+) 1428 WP_001280887.1 multidrug transporter subunit MdtD -
  NML23_RS22440 (NML23_22440) cytR 4622952..4623944 (-) 993 WP_000224476.1 ribose operon transcriptional repressor RbsR Regulator
  NML23_RS22445 (NML23_22445) rbsK 4623948..4624877 (-) 930 WP_001300603.1 ribokinase -
  NML23_RS22450 (NML23_22450) rbsB 4625003..4625893 (-) 891 WP_001056273.1 ribose ABC transporter substrate-binding protein RbsB -
  NML23_RS22455 (NML23_22455) rbsC 4625918..4626883 (-) 966 WP_000211858.1 ribose ABC transporter permease -
  NML23_RS22460 (NML23_22460) rbsA 4626888..4628393 (-) 1506 WP_000387756.1 ribose ABC transporter ATP-binding protein RbsA -
  NML23_RS22465 (NML23_22465) rbsD 4628401..4628820 (-) 420 WP_001364631.1 D-ribose pyranase -

Sequence

Protein


Download         Length: 330 a.a.        Molecular weight: 36584.88 Da        Isoelectric Point: 5.2141

>NTDB_id=609453 NML23_RS22440 WP_000224476.1 4622952..4623944(-) (cytR) [Escherichia coli strain EC21Z-101]
MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELNYAPSALARSLKLNQTHTIGMLITASTNPFYSELVRG
VERSCFERGYSLVLCNTEGDEQRMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLSIPDGYEVTGDFEFNGGFDAMRQLLSHPLRPQ
AVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDIELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQL
TPILMERGSA

Nucleotide


Download         Length: 993 bp        

>NTDB_id=609453 NML23_RS22440 WP_000224476.1 4622952..4623944(-) (cytR) [Escherichia coli strain EC21Z-101]
TTGGCTACAATGAAAGATGTTGCCCGCCTGGCGGGCGTTTCTACCTCAACAGTTTCTCACGTTATCAATAAAGATCGCTT
CGTCAGTGAAGCGATTACCGCCAAAGTTGAAGCGGCGATTAAAGAACTCAATTACGCGCCATCAGCCCTGGCGCGTAGCC
TCAAACTCAATCAAACACATACCATTGGCATGTTGATCACTGCCAGTACCAATCCTTTCTATTCAGAACTGGTGCGTGGC
GTTGAACGCAGCTGCTTCGAACGCGGTTATAGTCTCGTCCTTTGCAATACCGAAGGCGATGAACAGCGGATGAATCGCAA
TCTGGAAACGCTGATGCAAAAACGCGTTGATGGCTTGCTGTTACTGTGCACCGAAACGCATCAACCTTCGCGTGAAATCA
TGCAACGTTATCCGACAGTGCCTACTGTGATGATGGACTGGGCTCCGTTCGATGGCGACAGCGATCTTATTCAGGATAAC
TCGTTGCTGGGCGGAGACTTAGCAACGCAATATCTGATCGATAAAGGTCATACCCGTATCGCCTGTATTACCGGTCCGCT
GGATAAAACTCCGGCGCGCCTGCGGTTGGAAGGTTATCGGGCGGCGATGAAACGTGCGGGTCTCAGCATTCCTGATGGCT
ATGAAGTCACTGGTGATTTTGAATTTAACGGCGGGTTTGACGCCATGCGCCAACTGTTATCACATCCGCTGCGTCCTCAG
GCCGTCTTTACCGGAAATGACGCTATGGCTGTTGGCGTTTACCAGGCGTTATATCAGGCAGAGTTACAGGTTCCGCAGGA
TATCGCGGTGATTGGCTATGACGATATCGAACTGGCAAGCTTTATGACGCCACCATTAACCACTATCCACCAACCGAAAG
ATGAACTGGGGGAGCTGGCGATTGATGTACTCATCCATCGGATAACCCAGCCGACCCTTCAGCAACAACGATTACAACTT
ACTCCGATTCTGATGGAACGCGGTTCGGCTTAG

Domains

Predicted by InterProScan.

Periplasmic binding protein-like domain (Peripla_BP_3)

(169-329)

Bacterial regulatory proteins, lacI family (LacI)

(3-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A7ZTW4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cytR Vibrio parahaemolyticus RIMD 2210633

37.349

100

0.376
  cytR Vibrio cholerae C6706

39.088

93.03

0.364