Detailed information    

insolico Bioinformatically predicted

Overview


Name   brsR   Type   Regulator
Locus tag   EL277_RS00910 Genome accession   NZ_AP018936
Coordinates   167785..168225 (-) Length   146 a.a.
NCBI ID   WP_000861956.1    Uniprot ID   A0A0H2UNA2
Organism   Streptococcus pneumoniae strain NU83127     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 162785..173225
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL277_RS00880 (SPNU_0162) - 163046..164332 (+) 1287 WP_000278874.1 response regulator transcription factor -
  EL277_RS00885 (SPNU_0163) - 164384..164917 (+) 534 WP_000729030.1 hypothetical protein -
  EL277_RS00890 (SPNU_0164) nrdI 164995..165465 (+) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  EL277_RS00900 (SPNU_0165) - 165758..167020 (-) 1263 WP_000075807.1 NRAMP family divalent metal transporter -
  EL277_RS00905 (SPNU_0166) - 167330..167788 (-) 459 WP_000745059.1 DUF3021 domain-containing protein -
  EL277_RS00910 (SPNU_0167) brsR 167785..168225 (-) 441 WP_000861956.1 LytTR family DNA-binding domain-containing protein Regulator
  EL277_RS00920 (SPNU_0168) - 168658..169524 (+) 867 WP_000537009.1 helix-turn-helix domain-containing protein -
  EL277_RS12505 (SPNU_0169) - 169677..169805 (+) 129 WP_001257108.1 hypothetical protein -
  EL277_RS00925 (SPNU_0170) - 169850..170407 (+) 558 WP_000358739.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase -
  EL277_RS00930 (SPNU_0172) - 170628..171734 (+) 1107 WP_000608717.1 pyridoxal-dependent decarboxylase -
  EL277_RS00935 (SPNU_0173) - 171710..173101 (+) 1392 WP_000358548.1 hypothetical protein -

Sequence


Protein


Download         Length: 146 a.a.        Molecular weight: 17183.84 Da        Isoelectric Point: 5.3783

>NTDB_id=60945 EL277_RS00910 WP_000861956.1 167785..168225(-) (brsR) [Streptococcus pneumoniae strain NU83127]
MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=60945 EL277_RS00910 WP_000861956.1 167785..168225(-) (brsR) [Streptococcus pneumoniae strain NU83127]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAAGAAACCGAAAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGAAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains


Predicted by InterProScan.

(50-144)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A0H2UNA2

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363


Multiple sequence alignment