Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   LCF45_RS06105 Genome accession   NZ_CP084035
Coordinates   1203218..1203901 (+) Length   227 a.a.
NCBI ID   WP_002011351.1    Uniprot ID   R8DDT2
Organism   Bacillus sp. 41-22     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1198218..1208901
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LCF45_RS06085 (LCF45_06075) - 1199200..1200846 (+) 1647 WP_002125935.1 peptide ABC transporter substrate-binding protein -
  LCF45_RS06090 (LCF45_06080) - 1200877..1201080 (-) 204 WP_000559981.1 hypothetical protein -
  LCF45_RS06095 (LCF45_06085) spx 1201661..1202056 (+) 396 WP_002011348.1 transcriptional regulator Spx -
  LCF45_RS06100 (LCF45_06090) - 1202107..1202781 (-) 675 WP_002030376.1 TerC family protein -
  LCF45_RS06105 (LCF45_06095) mecA 1203218..1203901 (+) 684 WP_002011351.1 adaptor protein MecA Regulator
  LCF45_RS06110 (LCF45_06100) - 1203974..1205518 (+) 1545 WP_002064255.1 cardiolipin synthase -
  LCF45_RS06115 (LCF45_06105) - 1205610..1206845 (+) 1236 WP_263894707.1 competence protein CoiA -
  LCF45_RS06120 (LCF45_06110) pepF 1206896..1208722 (+) 1827 WP_002134970.1 oligoendopeptidase F Regulator

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 27029.17 Da        Isoelectric Point: 4.0116

>NTDB_id=609165 LCF45_RS06105 WP_002011351.1 1203218..1203901(+) (mecA) [Bacillus sp. 41-22]
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAEL
SKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQVGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELH
SFEDRYYVYVEFDEVLHDEEEIDRILSIVLEYGEESTLTIHRVSEYGKQVVKERALETIRNNFPPKM

Nucleotide


Download         Length: 684 bp        

>NTDB_id=609165 LCF45_RS06105 WP_002011351.1 1203218..1203901(+) (mecA) [Bacillus sp. 41-22]
TTGGATATTGAAAGAATTAATGACCATACGATGAAATTTTTTATTACGTACATTGATATAGAGGATAGAGGGTTTAATCG
TGAAGAAATTTGGTATGATCGCGAACGAAGTGAAGAGCTCTTTTGGGAGATGATGGACGAAGCTCGTGATCATGATGATT
TCTTTATCGATGGGCCGTTATGGATCCAAGTGCAAGCAGTCGATAAAGGGATTGAAGTACTTGTAACGAAAGCGGAGCTT
TCAAAGGATGGACAAAAGCTGGAACTACCAATAGGTGTAGACAAAATTATAGACATTCCTCTAGATGAAGGCATCGAATC
ATTATTCCAGCAAGAATTAGTGGAAGAGGTAGAAGAACAAGTAGGAACAAACTTTAATGAAGATGGTACGTTTGGCTTTT
TAATTAAGTTTAATGATTTTGAAGATGTTATTTCATTAAGTCATCGTCTTATCTTTGAAGATATAAAAGATGAATTACAT
TCATTTGAGGACCGATATTATGTATATGTGGAATTCGATGAAGTGCTACATGATGAAGAAGAAATTGATCGTATTTTAAG
TATTGTTTTAGAATATGGAGAAGAATCTACTTTAACGATTCACCGTGTAAGTGAGTATGGGAAACAGGTTGTGAAAGAGC
GTGCGCTTGAGACAATTCGCAACAATTTCCCTCCTAAAATGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB R8DDT2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

54.386

100

0.546