Detailed information    

insolico Bioinformatically predicted

Overview

Name   recP/tkt   Type   Machinery gene
Locus tag   NMK49_RS06235 Genome accession   NZ_CP101124
Coordinates   1285187..1287175 (+) Length   662 a.a.
NCBI ID   WP_000481443.1    Uniprot ID   P66962
Organism   Staphylococcus aureus subsp. aureus RN4220     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1280187..1292175
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMK49_RS06195 rpmG 1280268..1280417 (+) 150 WP_001265708.1 50S ribosomal protein L33 -
  NMK49_RS06200 rpsN 1280871..1281140 (+) 270 WP_001085655.1 30S ribosomal protein S14 -
  NMK49_RS06205 guaC 1281297..1282274 (+) 978 WP_000688126.1 GMP reductase -
  NMK49_RS06215 - 1282296..1283312 (+) 1017 WP_001789887.1 CAP domain-containing protein -
  NMK49_RS06220 dinR/lexA 1283692..1284315 (-) 624 WP_001208760.1 transcriptional repressor LexA Regulator
  NMK49_RS06225 sosA 1284458..1284691 (+) 234 WP_000499647.1 DNA damage-induced cell division inhibitor SosA -
  NMK49_RS06230 - 1284827..1285066 (+) 240 WP_000071351.1 DUF896 domain-containing protein -
  NMK49_RS06235 recP/tkt 1285187..1287175 (+) 1989 WP_000481443.1 transketolase Machinery gene
  NMK49_RS06240 - 1287453..1287695 (+) 243 WP_000246909.1 YneF family protein -
  NMK49_RS06245 - 1287682..1287780 (+) 99 WP_001789897.1 hypothetical protein -
  NMK49_RS06250 - 1287874..1288341 (+) 468 WP_000966142.1 CcdC family protein -
  NMK49_RS06255 sbcD 1288465..1289586 (+) 1122 WP_000691284.1 exonuclease subunit SbcD -

Sequence

Protein


Download         Length: 662 a.a.        Molecular weight: 72250.84 Da        Isoelectric Point: 4.7072

>NTDB_id=608926 NMK49_RS06235 WP_000481443.1 1285187..1287175(+) (recP/tkt) [Staphylococcus aureus subsp. aureus RN4220]
MFNEKDQLAVDTLRALSIDTIEKANSGHPGLPMGAAPMAYTLWTRHLNFNPQSKDYFNRDRFVLSAGHGSALLYSLLHVS
GSLELEELKQFRQWGSKTPGHPEYRHTDGVEVTTGPLGQGFAMSVGLALAEDHLAGKFNKEGYNVVDHYTYVLASDGDLM
EGISHEAASFAGHNKLSKLVVLYDSNDISLDGELNKAFSENTKARFEAYGWNYLLVKDGNDLEEIDKAITTAKSQEGPTI
IEVKTTIGFGSPNKAGTNGVHGAPLGEVERKLTFENYGLDPEKRFNVSEEVYEIFQNTMLKRANEDESQWNSLLEKYAET
YPELAEEFKLAISGKLPKNYKDELPRFELGHNGASRADSGTVIQAISKTVPSFFGGSADLAGSNKSNVNDATDYSSETPE
GKNVWFGVREFAMGAAVNGMAAHGGLHPYGATFFVFSDYLKPALRLSSIMGLNATFIFTHDSIAVGEDGPTHEPIEQLAG
LRAIPNMNVIRPADGNETRVAWEVALESESTPTSLVLTRQNLPVLDVPEDVVEEGVRKGAYTVYGSEETPEFLLLASGSE
VSLAVEAAKDLEKQGKSVRVVSMPNWNAFEQQSEEYKESVIPSSVTKRVAIEMASPLGWHKYVGTAGKVIAIDGFGASAP
GDLVVEKYGFTKENILNQVMSL

Nucleotide


Download         Length: 1989 bp        

>NTDB_id=608926 NMK49_RS06235 WP_000481443.1 1285187..1287175(+) (recP/tkt) [Staphylococcus aureus subsp. aureus RN4220]
ATGTTTAATGAAAAAGATCAATTAGCTGTTGATACGCTACGTGCACTAAGTATCGACACAATCGAAAAAGCGAATTCTGG
TCATCCAGGATTACCTATGGGAGCTGCCCCAATGGCTTACACTTTGTGGACACGTCATCTGAATTTTAATCCACAATCTA
AAGATTACTTCAATAGAGACCGTTTCGTATTATCTGCAGGGCATGGTTCAGCATTATTGTATAGCTTGTTACATGTTTCT
GGTAGTTTAGAATTAGAAGAATTAAAGCAATTTAGACAATGGGGTTCTAAAACACCAGGTCATCCTGAATACAGACATAC
AGATGGTGTAGAAGTTACTACCGGACCACTTGGACAAGGTTTTGCTATGTCAGTAGGATTAGCTTTAGCAGAAGATCACC
TAGCAGGGAAATTTAATAAAGAAGGATATAATGTTGTAGATCATTACACATATGTATTAGCTTCTGACGGTGATTTAATG
GAAGGTATATCGCATGAAGCAGCTTCATTTGCTGGACATAATAAATTAAGTAAATTAGTTGTTTTATACGATTCAAATGA
TATTTCATTAGATGGCGAATTAAACAAAGCTTTTTCTGAAAACACAAAAGCTCGTTTTGAAGCATATGGTTGGAATTACT
TACTAGTTAAAGATGGTAATGATTTAGAAGAAATTGATAAAGCGATTACTACAGCTAAATCTCAAGAAGGACCAACGATT
ATTGAAGTTAAAACAACAATCGGATTTGGTTCACCGAATAAAGCAGGAACTAATGGTGTTCATGGGGCACCTTTAGGTGA
AGTTGAAAGAAAATTAACATTCGAAAATTACGGTTTAGATCCTGAAAAACGTTTTAATGTTTCAGAAGAGGTATACGAAA
TTTTCCAAAATACTATGTTAAAACGTGCTAATGAAGATGAATCTCAATGGAATTCATTATTAGAAAAATATGCAGAAACA
TATCCTGAATTAGCAGAAGAATTTAAATTAGCGATTAGTGGTAAATTGCCTAAAAATTATAAGGATGAATTACCACGTTT
TGAACTGGGTCATAATGGTGCATCTCGTGCTGATTCTGGTACTGTTATTCAAGCAATCAGTAAAACTGTCCCTTCATTCT
TTGGTGGATCAGCAGACCTTGCTGGTTCAAACAAATCCAATGTAAATGATGCAACTGATTATAGTTCTGAAACACCTGAA
GGTAAAAATGTGTGGTTTGGTGTACGTGAATTTGCTATGGGTGCTGCTGTAAATGGTATGGCTGCACATGGAGGTTTACA
TCCATATGGTGCAACATTCTTCGTATTTAGTGATTATTTAAAACCAGCGTTACGTTTATCATCAATTATGGGATTAAATG
CAACGTTCATCTTCACACATGATTCAATTGCAGTAGGTGAAGATGGTCCTACTCATGAACCAATTGAGCAATTAGCTGGA
TTAAGAGCCATTCCAAATATGAATGTTATCCGTCCTGCTGATGGTAATGAAACAAGAGTAGCATGGGAAGTTGCCTTAGA
ATCTGAATCTACACCTACTTCATTAGTATTGACACGTCAAAACTTACCGGTATTAGATGTACCAGAAGATGTAGTTGAAG
AAGGCGTTCGAAAAGGTGCCTATACAGTTTATGGCTCTGAAGAGACACCAGAATTCCTATTATTAGCTTCAGGTTCAGAA
GTTAGTCTTGCAGTTGAAGCTGCTAAAGATCTTGAAAAACAAGGTAAATCAGTACGTGTTGTTTCAATGCCTAACTGGAA
TGCATTTGAACAACAATCTGAAGAATATAAAGAATCAGTTATTCCATCAAGCGTAACAAAACGTGTTGCGATTGAAATGG
CTTCACCGCTTGGATGGCATAAATATGTAGGTACTGCAGGTAAAGTTATTGCTATTGACGGCTTTGGCGCAAGTGCACCT
GGCGATTTAGTAGTTGAAAAATATGGATTTACAAAAGAAAATATCTTAAACCAAGTTATGAGCTTATAA

Domains

Predicted by InterProScan.

Transketolase, thiamine diphosphate binding domain (Transketolase_N)

(6-337)

Transketolase, C-terminal domain (Transketolase_C)

(548-655)

Transketolase, pyrimidine binding domain (Transket_pyr)

(359-523)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66962

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recP/tkt Streptococcus pneumoniae TIGR4

55.105

100

0.554