Detailed information NTG0060874

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: EL269_RS03915
• Genome accession: NZ_AP018935
• Coordinates: 699972..700757 (+)
• Length: 261 a.a.
• NCBI ID: WP_000825431.1
• Uniprot ID: Q8E0P2
• Organism: Streptococcus agalactiae strain HU-GS5823
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 694972..705757

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL269_RS03885 (SAGS_0730)	-	696089..696532 (+)	444	WP_001048166.1	hypothetical protein	-
EL269_RS03890 (SAGS_0731)	-	696617..696883 (+)	267	WP_001865676.1	hypothetical protein	-
EL269_RS03895	-	696984..697112 (+)	129	WP_000962057.1	hypothetical protein	-
EL269_RS03900 (SAGS_0732)	-	697121..697441 (+)	321	WP_001865677.1	hypothetical protein	-
EL269_RS03905 (SAGS_0733)	-	697538..698209 (+)	672	WP_000891268.1	ATP-binding cassette domain-containing protein	-
EL269_RS03910 (SAGS_0734)	-	698266..699711 (-)	1446	WP_000750933.1	FAD/NAD(P)-binding protein	-
EL269_RS03915 (SAGS_0735)	endA	699972..700757 (+)	786	WP_000825431.1	DNA/RNA non-specific endonuclease	Machinery gene
EL269_RS03920 (SAGS_0736)	-	700835..701473 (-)	639	WP_000478529.1	VTT domain-containing protein	-
EL269_RS03925 (SAGS_0737)	-	701690..702346 (+)	657	WP_000121094.1	ATP-binding cassette domain-containing protein	-
EL269_RS03930 (SAGS_0738)	-	702343..703116 (+)	774	WP_000012390.1	ABC transporter permease	-
EL269_RS03935 (SAGS_0739)	-	703280..704098 (+)	819	WP_126476296.1	phosphate ABC transporter ATPase	-
EL269_RS03940 (SAGS_0740)	-	704135..705019 (-)	885	WP_000354840.1	LysR family transcriptional regulator	-
EL269_RS03945 (SAGS_0741)	-	705212..705718 (+)	507	Protein_675	PTS sugar transporter subunit IIC	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 29424.86 Da
• Isoelectric Point: 8.9989

>NTDB_id=60874 EL269_RS03915 WP_000825431.1 699972..700757(+) (endA) [Streptococcus agalactiae strain HU-GS5823]
MKRLHKLFITVIATLGMLGVMTFGLPTQPQNVTPIVHADVNSSVDTSQEFQNNLKNAIGNLPFQYVNGIYELNNNQTNLN
ADVNVKAYVQNTIDNQQRLSTANAMLDRTIRQYQNRRDTTLPDANWKPLGWHQVATNDHYGHAVDKGHLIAYALAGNFKG
WDASVSNPQNVVTQTAHSNQSNQKINRGQNYYESLVRKAVDQNKRVRYRVTPLYRNDTDLVPFAMHLEAKSQDGTLEFNV
AIPNTQASYTMDYATGEITLN

Nucleotide

• Length: 786 bp

>NTDB_id=60874 EL269_RS03915 WP_000825431.1 699972..700757(+) (endA) [Streptococcus agalactiae strain HU-GS5823]
ATGAAAAGATTACATAAACTGTTTATAACCGTAATTGCTACATTAGGTATGTTGGGGGTAATGACCTTTGGTCTTCCAAC
GCAGCCGCAAAACGTAACGCCGATAGTACATGCTGATGTCAATTCATCTGTTGATACGAGCCAGGAATTTCAAAATAATT
TAAAAAATGCTATTGGTAACCTACCATTTCAATATGTTAATGGTATTTATGAATTAAATAATAATCAGACAAATTTAAAT
GCTGATGTCAATGTTAAAGCGTATGTTCAAAATACAATTGACAATCAACAAAGACTATCAACTGCTAATGCAATGCTTGA
TAGAACCATTCGTCAATATCAAAATCGCAGAGATACCACTCTTCCCGATGCAAATTGGAAACCATTAGGTTGGCATCAAG
TAGCTACTAATGACCATTATGGACATGCAGTCGACAAGGGGCATTTAATTGCCTATGCTTTAGCTGGAAATTTCAAAGGT
TGGGATGCTTCCGTGTCAAATCCTCAAAATGTTGTCACACAAACAGCTCATTCCAACCAATCAAATCAAAAAATCAATCG
TGGACAAAATTATTATGAAAGCTTAGTTCGTAAGGCGGTTGACCAAAACAAACGTGTTCGTTACCGTGTAACTCCATTGT
ACCGTAATGATACTGATTTAGTTCCATTTGCAATGCACCTAGAAGCTAAATCACAAGATGGCACATTAGAATTTAATGTT
GCTATTCCAAACACACAAGCATCATACACTATGGATTATGCAACAGGAGAAATAACACTAAATTAA

Domains

Predicted by InterProScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (77-235)

3D structure

• AlphaFold DB: Q8E0P2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	51.515	75.862	0.391
endA	Streptococcus pneumoniae D39	51.515	75.862	0.391
endA	Streptococcus pneumoniae R6	51.515	75.862	0.391
endA	Streptococcus pneumoniae TIGR4	51.515	75.862	0.391