Detailed information NTG0060815

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: D5070_RS09445
• Genome accession: NZ_AP018923
• Coordinates: 1851016..1852290 (+)
• Length: 424 a.a.
• NCBI ID: WP_001279338.1
• Uniprot ID: A0A0H2XGV4
• Organism: Staphylococcus aureus strain JMUB3031
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1846016..1857290

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D5070_RS09425	-	1847340..1847435 (+)	96	WP_031789489.1	hypothetical protein	-
D5070_RS09430 (JMUB3031_1762)	-	1847396..1848526 (-)	1131	WP_000721707.1	HAD family hydrolase	-
D5070_RS09435 (JMUB3031_1763)	nagE	1848633..1850099 (-)	1467	WP_000276362.1	N-acetylglucosamine-specific PTS transporter subunit IIBC	-
D5070_RS09440 (JMUB3031_1764)	-	1850227..1850844 (-)	618	WP_000287588.1	lysophospholipid acyltransferase family protein	-
D5070_RS09445 (JMUB3031_1765)	htrA	1851016..1852290 (+)	1275	WP_001279338.1	S1C family serine protease	Regulator
D5070_RS09450 (JMUB3031_1766)	tyrS	1852384..1853646 (-)	1263	WP_000186029.1	tyrosine--tRNA ligase	-
D5070_RS09455 (JMUB3031_1767)	-	1854027..1854932 (+)	906	WP_000184370.1	transglycosylase domain-containing protein	-
D5070_RS09460	-	1854912..1855004 (-)	93	WP_001789987.1	hypothetical protein	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 45802.98 Da
• Isoelectric Point: 9.9696

>NTDB_id=60815 D5070_RS09445 WP_001279338.1 1851016..1852290(+) (htrA) [Staphylococcus aureus strain JMUB3031]
MSDFNHTDHSTTNHSQTPRYRRPKFPWFKTVIVALIAGIIGALLVLGIGKVLNSTILNKDGSTVQTTNNKGGNQLDGQSK
KFGTVHEMIKSVSPTIVGVINMQKASSVDDLLKGKSSKPSEAGVGSGVIYQINNNSAYIVTNNHVIDGANEIRVQLHNKK
QVKAKLVGKDAVTDIAVLKIENTKGIKAIQFANSSKVQTGDSVFAMGNPLGLQFANSVTSGIISASERTIDAETTGGNTK
VSVLQTDAAINPGNSGGALVDINGNLVGINSMKIAATQVEGIGFAIPSNEVKVTIEQLVKHGKIDRPSIGIGLINLKDIP
EEEREQLHTDREDGIYVAKADSDIDLKKGDIITEIDGKKIKDDVDLRSYLYENKKPGESVTVTVIRDGKTKEVKVKLKQQ
KEQPKRQSRSERQSPGQGDRDFFR

Nucleotide

• Length: 1275 bp

>NTDB_id=60815 D5070_RS09445 WP_001279338.1 1851016..1852290(+) (htrA) [Staphylococcus aureus strain JMUB3031]
ATGTCAGATTTTAATCATACAGATCATTCTACAACAAACCATAGCCAAACACCTAGATACAGAAGACCTAAATTTCCATG
GTTTAAAACAGTCATCGTTGCATTGATTGCTGGAATTATTGGTGCACTTCTAGTACTTGGTATAGGCAAAGTATTAAATA
GTACAATTTTAAATAAAGATGGTTCAACTGTTCAGACAACAAATAATAAAGGTGGCAATCAATTAGACGGTCAAAGCAAG
AAATTCGGTACCGTTCATGAAATGATAAAATCTGTCTCCCCTACAATTGTTGGAGTTATTAACATGCAAAAAGCATCAAG
TGTAGACGACTTATTAAAAGGCAAATCATCTAAACCATCTGAAGCTGGAGTAGGTTCAGGTGTTATCTATCAAATAAACA
ACAATTCAGCTTATATCGTTACAAACAATCATGTTATTGATGGCGCAAATGAAATTAGAGTCCAATTACATAATAAAAAA
CAAGTTAAAGCGAAATTAGTTGGTAAAGATGCAGTAACTGATATTGCTGTACTTAAAATTGAAAATACAAAAGGTATTAA
AGCGATTCAATTCGCCAACTCTTCAAAAGTACAAACTGGCGATAGCGTATTCGCAATGGGTAACCCATTAGGATTACAAT
TTGCTAACTCTGTAACATCTGGTATCATTTCAGCAAGCGAACGTACTATTGACGCTGAGACAACTGGTGGCAATACAAAA
GTCAGCGTTCTTCAAACAGATGCTGCTATTAACCCAGGTAACTCAGGTGGCGCATTAGTAGATATTAATGGTAATTTAGT
TGGTATTAACTCAATGAAAATTGCTGCGACACAAGTTGAAGGTATCGGGTTTGCTATTCCAAGTAATGAAGTTAAAGTAA
CAATTGAACAACTTGTAAAACATGGTAAAATTGACCGCCCTTCGATTGGTATTGGTTTAATTAATTTGAAAGATATTCCT
GAAGAAGAGCGCGAGCAACTTCATACTGATAGAGAAGACGGTATTTATGTCGCCAAAGCTGATAGTGATATTGATCTTAA
AAAAGGTGATATTATTACAGAAATTGATGGCAAGAAAATTAAAGATGATGTTGATTTAAGAAGCTATTTATATGAAAATA
AAAAACCTGGTGAATCAGTCACTGTTACCGTTATCCGTGATGGTAAAACAAAAGAAGTTAAAGTGAAATTAAAACAACAA
AAAGAACAACCAAAACGTCAAAGCCGATCAGAACGTCAATCACCTGGCCAAGGCGATAGAGATTTCTTTAGATAA

Domains

Predicted by InterProScan.

• Trypsin-like peptidase domain (Trypsin_2) (125-269)

• PDZ domain (PDZ_2) (307-397)

3D structure

• AlphaFold DB: A0A0H2XGV4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	39.055	94.811	0.37