Detailed information NTG0608039

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: LB317_RS09155
• Genome accession: NZ_CP083805
• Coordinates: 1937050..1938093 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus argenteus strain 1801221
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1932050..1943093

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LB317_RS09125 (LB317_09135)	-	1932461..1933708 (-)	1248	WP_000656301.1	aminopeptidase	-
LB317_RS09130 (LB317_09140)	-	1933720..1933920 (-)	201	WP_000180459.1	DUF1128 family protein	-
LB317_RS09135 (LB317_09145)	-	1934067..1934531 (+)	465	WP_000228669.1	low molecular weight protein-tyrosine-phosphatase	-
LB317_RS09140 (LB317_09150)	-	1934538..1934813 (+)	276	WP_000428174.1	YtxH domain-containing protein	-
LB317_RS09145 (LB317_09155)	-	1935092..1936315 (+)	1224	WP_000037065.1	YihY/virulence factor BrkB family protein	-
LB317_RS09150 (LB317_09160)	vraR	1936431..1937060 (-)	630	WP_000153529.1	two-component system response regulator VraR	Regulator
LB317_RS09155 (LB317_09165)	vraS	1937050..1938093 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
LB317_RS09160 (LB317_09170)	liaF	1938090..1938791 (-)	702	WP_031788217.1	cell wall-active antibiotics response protein LiaF	-
LB317_RS09165 (LB317_09175)	-	1938806..1939192 (-)	387	WP_001110170.1	hypothetical protein	-
LB317_RS09170 (LB317_09180)	map	1939413..1940171 (-)	759	WP_031788218.1	type I methionyl aminopeptidase	-
LB317_RS09175 (LB317_09185)	-	1940702..1941688 (+)	987	WP_031788370.1	FUSC family protein	-
LB317_RS09180 (LB317_09190)	-	1942320..1943042 (-)	723	WP_031787877.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=608039 LB317_RS09155 WP_001017131.1 1937050..1938093(-) (vraS) [Staphylococcus argenteus strain 1801221]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=608039 LB317_RS09155 WP_001017131.1 1937050..1938093(-) (vraS) [Staphylococcus argenteus strain 1801221]
ATGAACCATTATATTAGAACAATTGGTTCGATGCTCATCTTAGTATACAGCATGCTAGCGGCATTTCTTTTTATAGATAA
AGTTTTCGTTAATATTATTTATTTTCAAGGCATGTTTTATACACAAATATTTGGGATTCCAGTCTTTTTATTTTTAAATC
TCATTATCATTTTATTGTGTATCATCGTCGGATCGGTGCTTGCCTACAAAATTAATCAACAAAATGATTGGATTAAGACA
CAAATTGAGCGTTCTATGGAAGGCGAAACAGTAGGTATCAATGATCAAAATATAGAAATATATAGTGAAACATTAGATTT
ATATCATACGTTAGTACCTTTAAATCAAGAATTGCATAAGTTAAGACTCAAAACGCAAAATTTAACAAATGAAAATTACA
ATATTAATGATGTTAAAGTTAAAAAGATTATCGAAGATGAAAGACAACGTTTAGCTAGAGAACTACACGACTCTGTTAGT
CAACAACTTTTTGCGGCAAGTATGATGTTATCTGCAATTAAAGAAACGAAATTAGAACCACCTTTAGATCAACAAATACC
TATTTTAGAGAAAATGGTTCAAGATTCTCAGTTAGAAATGCGTGCTTTGCTGCTACACTTAAGACCACTCGGCTTGAAAG
ATAAGTCATTAGGCGAAGGTATTAAAGATTTAGTTATTGATTTACAAAAGAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCAAAAGGTATTGAAGATCATTTATTTAGAATTACGCAAGAAGCAATATCTAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTAGAATTATTTAATAAAGATGATTATTTATTGTTAAGGATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCACTACCAGATTCAGGTACACGTATTGAGGTGAAAGCACCTCTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1