Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   K9B11_RS13965 Genome accession   NZ_CP083728
Coordinates   2797151..2797867 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain MR254     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2792151..2802867
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K9B11_RS13945 (K9B11_13945) - 2793245..2794195 (+) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -
  K9B11_RS13950 (K9B11_13950) - 2794344..2795828 (+) 1485 WP_224433974.1 sucrose-6-phosphate hydrolase -
  K9B11_RS13955 (K9B11_13955) - 2795825..2796784 (+) 960 WP_001253312.1 carbohydrate kinase family protein -
  K9B11_RS13960 (K9B11_13960) - 2796972..2797079 (-) 108 WP_001790167.1 hypothetical protein -
  K9B11_RS13965 (K9B11_13965) agrA 2797151..2797867 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  K9B11_RS13970 (K9B11_13970) agrC 2797886..2799178 (-) 1293 WP_001554031.1 quorum-sensing sensor histidine kinase AgrC -
  K9B11_RS13975 (K9B11_13975) agrD 2799203..2799343 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  K9B11_RS13980 (K9B11_13980) agrB 2799340..2799909 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  K9B11_RS14440 hld 2800199..2800279 (+) 81 WP_000046022.1 delta-hemolysin -
  K9B11_RS13990 (K9B11_13990) - 2800876..2801661 (-) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  K9B11_RS13995 (K9B11_13995) - 2801990..2802649 (-) 660 WP_224433975.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=607543 K9B11_RS13965 WP_000688492.1 2797151..2797867(-) (agrA) [Staphylococcus aureus strain MR254]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=607543 K9B11_RS13965 WP_000688492.1 2797151..2797867(-) (agrA) [Staphylococcus aureus strain MR254]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1