Detailed information NTG0607539

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: K9B11_RS10800
• Genome accession: NZ_CP083728
• Coordinates: 2177644..2178531 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain MR254
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2172644..2183531

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K9B11_RS10770 (K9B11_10770)	-	2173376..2174137 (+)	762	WP_000323455.1	alpha/beta hydrolase	-
K9B11_RS10775 (K9B11_10775)	-	2174382..2174837 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
K9B11_RS14430	-	2174959..2175060 (+)	102	WP_000731972.1	SE2200 family small protein	-
K9B11_RS10785 (K9B11_10785)	-	2175120..2176544 (-)	1425	WP_000953744.1	alkaline phosphatase	-
K9B11_RS10790 (K9B11_10790)	-	2176742..2176942 (+)	201	WP_000604728.1	hypothetical protein	-
K9B11_RS10795 (K9B11_10795)	braR	2176968..2177633 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
K9B11_RS10800 (K9B11_10800)	braS	2177644..2178531 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
K9B11_RS10805 (K9B11_10805)	-	2178639..2179394 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
K9B11_RS10810 (K9B11_10810)	-	2179391..2181391 (+)	2001	WP_224433935.1	ABC transporter permease	-
K9B11_RS10815 (K9B11_10815)	-	2182050..2182163 (+)	114	WP_011447078.1	hypothetical protein	-
K9B11_RS10820 (K9B11_10820)	-	2182545..2182805 (+)	261	WP_001789910.1	hypothetical protein	-
K9B11_RS10825 (K9B11_10825)	-	2182815..2183312 (+)	498	WP_001065268.1	glutathione peroxidase	-
K9B11_RS10830 (K9B11_10830)	-	2183420..2183512 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=607539 K9B11_RS10800 WP_000143419.1 2177644..2178531(+) (braS) [Staphylococcus aureus strain MR254]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=607539 K9B11_RS10800 WP_000143419.1 2177644..2178531(+) (braS) [Staphylococcus aureus strain MR254]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997