Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   LAZ96_RS05505 Genome accession   NZ_CP083715
Coordinates   1046847..1047491 (-) Length   214 a.a.
NCBI ID   WP_014418762.1    Uniprot ID   A0A2Z4EIP2
Organism   Bacillus velezensis strain DMB05     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 1041847..1052491
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LAZ96_RS05470 (LAZ96_05470) - 1043032..1043463 (+) 432 WP_007613424.1 Na(+)/H(+) antiporter subunit B -
  LAZ96_RS05475 (LAZ96_05475) - 1043463..1043804 (+) 342 WP_022553706.1 Na(+)/H(+) antiporter subunit C -
  LAZ96_RS05480 (LAZ96_05480) - 1043797..1045278 (+) 1482 WP_017419418.1 Na+/H+ antiporter subunit D -
  LAZ96_RS05485 (LAZ96_05485) - 1045284..1045760 (+) 477 WP_017419419.1 Na+/H+ antiporter subunit E -
  LAZ96_RS05490 (LAZ96_05490) - 1045760..1046044 (+) 285 WP_012118311.1 Na(+)/H(+) antiporter subunit F1 -
  LAZ96_RS05495 (LAZ96_05495) mnhG 1046028..1046402 (+) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  LAZ96_RS05500 (LAZ96_05500) - 1046442..1046825 (-) 384 WP_017419422.1 hotdog fold thioesterase -
  LAZ96_RS05505 (LAZ96_05505) comA 1046847..1047491 (-) 645 WP_014418762.1 response regulator transcription factor Regulator
  LAZ96_RS05510 (LAZ96_05510) - 1047572..1049056 (-) 1485 Protein_1075 sensor histidine kinase -
  LAZ96_RS05515 (LAZ96_05515) - 1049170..1050320 (+) 1151 WP_087614160.1 IS3 family transposase -
  LAZ96_RS05520 (LAZ96_05520) - 1050354..1051163 (-) 810 WP_224446919.1 hypothetical protein -
  LAZ96_RS05525 (LAZ96_05525) comX 1051177..1051350 (-) 174 WP_012118314.1 competence pheromone ComX -
  LAZ96_RS05530 (LAZ96_05530) - 1051319..1052179 (-) 861 WP_157774448.1 polyprenyl synthetase family protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24302.70 Da        Isoelectric Point: 4.9953

>NTDB_id=607397 LAZ96_RS05505 WP_014418762.1 1046847..1047491(-) (comA) [Bacillus velezensis strain DMB05]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTQRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=607397 LAZ96_RS05505 WP_014418762.1 1046847..1047491(-) (comA) [Bacillus velezensis strain DMB05]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATAGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGTAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACACAGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCGATTGAATA
CAGCCTGACATCCATTTTTAATAAGCTGAATGTCGGCTCCCGCACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z4EIP2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

85.981

100

0.86