Detailed information NTG0607247

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: K3A99_RS13375
• Genome accession: NZ_CP083671
• Coordinates: 2683251..2684138 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain HL25870
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2678251..2689138

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K3A99_RS13345 (K3A99_002640)	-	2678260..2678352 (+)	93	WP_031774855.1	hypothetical protein	-
K3A99_RS13350 (K3A99_002641)	-	2678460..2678957 (-)	498	WP_001065267.1	glutathione peroxidase	-
K3A99_RS13355 (K3A99_002642)	-	2678967..2679227 (-)	261	WP_014937088.1	hypothetical protein	-
K3A99_RS13360 (K3A99_002643)	-	2679609..2679722 (-)	114	WP_014937089.1	hypothetical protein	-
K3A99_RS13365 (K3A99_002644)	-	2680391..2682391 (-)	2001	WP_000776741.1	ABC transporter permease	-
K3A99_RS13370 (K3A99_002645)	-	2682388..2683143 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
K3A99_RS13375 (K3A99_002646)	braS	2683251..2684138 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
K3A99_RS13380 (K3A99_002647)	braR	2684149..2684814 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
K3A99_RS13385 (K3A99_002648)	-	2684840..2685040 (-)	201	WP_000604731.1	hypothetical protein	-
K3A99_RS13390 (K3A99_002649)	-	2685238..2686662 (+)	1425	WP_000953736.1	alkaline phosphatase	-
K3A99_RS14060	-	2686722..2686823 (-)	102	WP_000731972.1	SE2200 family small protein	-
K3A99_RS13400 (K3A99_002651)	-	2686945..2687400 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
K3A99_RS13405 (K3A99_002652)	-	2687644..2688405 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=607247 K3A99_RS13375 WP_000143420.1 2683251..2684138(-) (braS) [Staphylococcus aureus strain HL25870]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=607247 K3A99_RS13375 WP_000143420.1 2683251..2684138(-) (braS) [Staphylococcus aureus strain HL25870]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993