Detailed information    

insolico Bioinformatically predicted

Overview

Name   cytR   Type   Regulator
Locus tag   NMD48_RS22850 Genome accession   NZ_CP100930
Coordinates   4629966..4630958 (-) Length   330 a.a.
NCBI ID   WP_000224470.1    Uniprot ID   P0ACQ1
Organism   Escherichia coli strain ET670     
Function   promote competence gene expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 4624966..4635958
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMD48_RS22840 (NMD48_22710) yieP 4627858..4628550 (+) 693 WP_001131169.1 FadR/GntR family transcriptional regulator -
  NMD48_RS22845 (NMD48_22715) mdtD 4628573..4630000 (+) 1428 WP_001280838.1 multidrug transporter subunit MdtD -
  NMD48_RS22850 (NMD48_22720) cytR 4629966..4630958 (-) 993 WP_000224470.1 ribose operon transcriptional repressor RbsR Regulator
  NMD48_RS22855 (NMD48_22725) rbsK 4630962..4631891 (-) 930 WP_001300603.1 ribokinase -
  NMD48_RS22860 (NMD48_22730) rbsB 4632017..4632907 (-) 891 WP_001056273.1 ribose ABC transporter substrate-binding protein RbsB -
  NMD48_RS22865 (NMD48_22735) rbsC 4632932..4633897 (-) 966 WP_000211858.1 ribose ABC transporter permease -
  NMD48_RS22870 (NMD48_22740) rbsA 4633902..4635407 (-) 1506 WP_000387752.1 ribose ABC transporter ATP-binding protein RbsA -
  NMD48_RS22875 (NMD48_22745) rbsD 4635415..4635834 (-) 420 WP_000715936.1 D-ribose pyranase -

Sequence

Protein


Download         Length: 330 a.a.        Molecular weight: 36611.90 Da        Isoelectric Point: 5.2141

>NTDB_id=607165 NMD48_RS22850 WP_000224470.1 4629966..4630958(-) (cytR) [Escherichia coli strain ET670]
MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELNYAPSALARSLKLNQTHTIGMLITASTNPFYSELVRG
VERSCFERGYSLVLCNTEGDEQRMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTGDFEFNGGFDAMRQLLSHPLRPQ
AVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDIELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQL
TPILMERGSA

Nucleotide


Download         Length: 993 bp        

>NTDB_id=607165 NMD48_RS22850 WP_000224470.1 4629966..4630958(-) (cytR) [Escherichia coli strain ET670]
TTGGCTACAATGAAAGATGTTGCCCGCCTGGCGGGCGTTTCTACCTCAACAGTTTCTCACGTTATCAATAAAGATCGCTT
CGTCAGTGAAGCGATTACCGCCAAAGTTGAAGCGGCGATTAAAGAACTCAATTACGCGCCATCAGCCCTGGCGCGTAGCC
TCAAACTCAATCAAACACATACCATTGGCATGTTGATCACTGCCAGTACCAATCCTTTCTATTCAGAACTGGTGCGTGGC
GTTGAACGCAGCTGCTTCGAACGCGGTTATAGTCTCGTCCTTTGCAATACCGAAGGCGATGAACAGCGGATGAATCGCAA
TCTGGAAACGCTGATGCAAAAACGCGTTGATGGTTTGCTGTTACTGTGCACCGAAACGCATCAACCTTCGCGTGAAATCA
TGCAACGTTATCCGACAGTGCCTACTGTGATGATGGACTGGGCTCCGTTCGATGGCGACAGCGATCTTATTCAGGATAAC
TCGTTGCTGGGCGGAGACTTAGCAACGCAATATCTGATCGATAAAGGTCATACCCGTATCGCCTGTATTACCGGTCCGCT
GGATAAAACTCCGGCGCGCCTGCGGTTGGAAGGTTATCGGGCGGCGATGAAACGTGCGGGTCTCAACATTCCTGATGGCT
ATGAAGTCACTGGTGATTTTGAATTTAACGGCGGGTTTGACGCCATGCGCCAACTGTTATCACATCCGCTGCGTCCTCAG
GCCGTCTTTACCGGAAATGACGCTATGGCTGTTGGCGTTTACCAGGCGTTATATCAGGCAGAGTTACAGGTTCCGCAGGA
TATCGCGGTGATTGGCTATGACGATATCGAACTGGCAAGCTTTATGACGCCACCATTAACCACTATCCACCAACCGAAAG
ATGAACTGGGGGAGCTGGCGATTGATGTACTCATCCATCGGATAACCCAGCCGACCCTTCAGCAACAACGATTACAACTT
ACTCCGATTCTGATGGAACGCGGTTCGGCTTAG

Domains

Predicted by InterProScan.

Periplasmic binding protein-like domain (Peripla_BP_3)

(169-329)

Bacterial regulatory proteins, lacI family (LacI)

(3-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0ACQ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cytR Vibrio parahaemolyticus RIMD 2210633

37.048

100

0.373
  cytR Vibrio cholerae C6706

39.088

93.03

0.364