Detailed information NTG0606813

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LA346_RS03365
• Genome accession: NZ_CP083627
• Coordinates: 625904..626941 (-)
• Length: 345 a.a.
• NCBI ID: WP_001813016.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain FDAARGOS_1508
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 620904..631941

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LA346_RS03340 (LA346_03340)	-	621643..622974 (-)	1332	WP_000390042.1	hemolysin family protein	-
LA346_RS03345 (LA346_03345)	endA	623265..624089 (-)	825	WP_001036791.1	DNA-entry nuclease EndA	Machinery gene
LA346_RS03350 (LA346_03350)	-	624128..624316 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
LA346_RS03355 (LA346_03355)	murA	624309..625592 (-)	1284	WP_000358032.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
LA346_RS03360 (LA346_03360)	-	625616..625846 (-)	231	WP_000250390.1	DUF1146 family protein	-
LA346_RS03365 (LA346_03365)	sepM	625904..626941 (-)	1038	WP_001813016.1	SepM family pheromone-processing serine protease	Regulator
LA346_RS03370 (LA346_03370)	coaD	626925..627413 (-)	489	WP_001280746.1	pantetheine-phosphate adenylyltransferase	-
LA346_RS03375 (LA346_03375)	rsmD	627403..627942 (-)	540	WP_000706963.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LA346_RS03380 (LA346_03380)	asnA	628007..628999 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
LA346_RS03385 (LA346_03385)	-	629111..629794 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
LA346_RS03390 (LA346_03390)	-	629850..630590 (-)	741	WP_000152679.1	RNA methyltransferase	-
LA346_RS03395 (LA346_03395)	-	630624..630902 (+)	279	WP_001174614.1	acylphosphatase	-
LA346_RS03400 (LA346_03400)	yidC	630980..631906 (+)	927	WP_000835955.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37609.64 Da
• Isoelectric Point: 4.9590

>NTDB_id=606813 LA346_RS03365 WP_001813016.1 625904..626941(-) (sepM) [Streptococcus pneumoniae strain FDAARGOS_1508]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKEIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIDLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=606813 LA346_RS03365 WP_001813016.1 625904..626941(-) (sepM) [Streptococcus pneumoniae strain FDAARGOS_1508]
ATGAAAAAAAAGATTAGATGGCCTTTGTATGTCATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTGGTGCCTTTGCC
CTACTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCTACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGAAATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGACTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588