Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NMD52_RS09705 Genome accession   NZ_CP100914
Coordinates   1981213..1981869 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain ET761     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1976213..1986869
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMD52_RS09670 (NMD52_09635) dcyD 1977092..1978078 (+) 987 WP_001724631.1 D-cysteine desulfhydrase -
  NMD52_RS09675 (NMD52_09640) tcyL 1978093..1978761 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NMD52_RS09680 (NMD52_09645) tcyN 1978758..1979510 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NMD52_RS09685 (NMD52_09650) sdiA 1979740..1980462 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  NMD52_RS09690 (NMD52_09655) yecF 1980530..1980754 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NMD52_RS09695 (NMD52_09660) yecU 1980741..1980917 (-) 177 WP_000590344.1 protein YecU -
  NMD52_RS09700 - 1980955..1981071 (-) 117 WP_001302039.1 hypothetical protein -
  NMD52_RS09705 (NMD52_09665) letA 1981213..1981869 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NMD52_RS09710 (NMD52_09670) uvrC 1981866..1983698 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NMD52_RS09715 (NMD52_09675) pgsA 1983755..1984303 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NMD52_RS09735 (NMD52_09695) yecA 1984953..1985618 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=606799 NMD52_RS09705 WP_000611335.1 1981213..1981869(+) (letA) [Escherichia coli strain ET761]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=606799 NMD52_RS09705 WP_000611335.1 1981213..1981869(+) (letA) [Escherichia coli strain ET761]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486