Detailed information NTG0606305

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: K9N56_RS15470
• Genome accession: NZ_CP083580
• Coordinates: 3035893..3038223 (-)
• Length: 776 a.a.
• NCBI ID: WP_006637630.1
• Uniprot ID: M5P6B2
• Organism: Bacillus sp. PM8313
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 3030893..3043223

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K9N56_RS15440 (K9N56_15440)	-	3031094..3031417 (-)	324	WP_006637624.1	YqxA family protein	-
K9N56_RS15445 (K9N56_15445)	spoIIP	3031435..3032637 (-)	1203	WP_006637625.1	stage II sporulation protein P	-
K9N56_RS15450 (K9N56_15450)	gpr	3032772..3033878 (-)	1107	WP_006637626.1	GPR endopeptidase	-
K9N56_RS15455 (K9N56_15455)	rpsT	3034084..3034350 (+)	267	WP_006637627.1	30S ribosomal protein S20	-
K9N56_RS15460 (K9N56_15460)	holA	3034398..3035438 (-)	1041	WP_006637628.1	DNA polymerase III subunit delta	-
K9N56_RS15465 (K9N56_15465)	-	3035671..3035802 (+)	132	WP_006637629.1	YqzM family protein	-
K9N56_RS15470 (K9N56_15470)	comEC	3035893..3038223 (-)	2331	WP_006637630.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
K9N56_RS15475 (K9N56_15475)	-	3038230..3038799 (-)	570	WP_006637631.1	ComE operon protein 2	-
K9N56_RS15480 (K9N56_15480)	comEA	3038867..3039490 (-)	624	WP_373926326.1	helix-hairpin-helix domain-containing protein	Machinery gene
K9N56_RS15485 (K9N56_15485)	comER	3039577..3040398 (+)	822	WP_006637633.1	late competence protein ComER	-
K9N56_RS15490 (K9N56_15490)	-	3040466..3041221 (-)	756	WP_006637634.1	class I SAM-dependent DNA methyltransferase	-
K9N56_RS15495 (K9N56_15495)	rsfS	3041221..3041574 (-)	354	WP_006637635.1	ribosome silencing factor	-
K9N56_RS15500 (K9N56_15500)	yqeK	3041588..3042151 (-)	564	WP_006637636.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
K9N56_RS15505 (K9N56_15505)	-	3042141..3042710 (-)	570	WP_006637637.1	nicotinate-nucleotide adenylyltransferase	-
K9N56_RS15510 (K9N56_15510)	yhbY	3042729..3043019 (-)	291	WP_006637638.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 85558.84 Da
• Isoelectric Point: 9.5265

>NTDB_id=606305 K9N56_RS15470 WP_006637630.1 3035893..3038223(-) (comEC) [Bacillus sp. PM8313]
MGLLYRILPCGAISAAAGIASAQSSSFLPLIIFLSLLFIFSQIKKQFLLFFICTVICGFYMIYFMAIDSSNTTRYKEGAF
RAYMSVRDIPRIDGDRLAFTAEMAEGEAVKANYILQSPQEKAALSKLEPGSTCFMTGVLKTPKRATVPGTFDRKEYLRQQ
GIHWNFAVQSIKGCQSGGGPASFLLKIRKAGLGFIEKHVPETSAGIVQALVFGDRFLIEQDVLDGYQSLGIIHLLAISGL
HVGILSAVLFYMLLRIGITREHAKWCLIMMLPAAVMLTGAAPSVLRAAFMSEIYLLSSLFKNRLRGAQVLSIAWLGLLLF
NPYMLFQAGFQLSFAASFVFILSKEILLKPKHQTVRLLLASFVAQLGSLPILLFHFQEVSFLSVLMNLCFVPFYVFIVMP
LSFGGLLILLVAPPLGNLAMGVLDWLLGWSHWAVKAASSLEIFTFSAVKPDVIHLLFYIASICVLLMSIEKAISCKTLAI
PACLLASAFLFHAAAPHFIGSGEVTMLDVGQGDSIYISAPGQKGNVLIDTGGIVSFKKEAWRERKKDVSLGERVLIPFLA
SKGVKQLDALILTHADHDHMGEAEILIGKNKVKQLIVPKGYAAEPADEKLLRFALERGVDVKTAKRGDRLVIGDLVFYVL
SPETADKNSKNNSSLVLWMNAGGFSWLLTGDLEKEGEREMLKAYPRLKADILKVGHHGSKGSTGEELINRIEPKAALISA
GENNRYRHPHKEVLEILKRHQVKVFRTDRDGAVQYLFGRGDGTFLLHPPYDKVYSP

Nucleotide

• Length: 2331 bp

>NTDB_id=606305 K9N56_RS15470 WP_006637630.1 3035893..3038223(-) (comEC) [Bacillus sp. PM8313]
ATGGGTCTTCTCTACCGCATCCTTCCCTGCGGAGCAATTTCAGCAGCAGCCGGAATTGCTTCCGCCCAATCTTCTTCTTT
TCTCCCCCTCATCATCTTTTTAAGTCTGCTTTTCATCTTCAGTCAGATCAAGAAGCAATTTCTCCTTTTTTTCATTTGTA
CAGTCATCTGCGGTTTTTATATGATTTATTTTATGGCCATTGACAGTTCGAATACGACTCGCTACAAGGAAGGCGCTTTC
CGTGCGTACATGTCTGTTCGCGATATTCCGAGAATAGACGGGGACCGTCTCGCTTTCACTGCCGAAATGGCTGAAGGAGA
AGCGGTGAAAGCGAACTACATCCTTCAGTCTCCACAGGAAAAAGCGGCGCTTTCGAAGCTTGAGCCGGGCAGTACATGTT
TCATGACAGGCGTATTAAAAACTCCTAAGAGAGCAACTGTACCCGGGACGTTTGATCGTAAAGAATATCTGCGCCAGCAG
GGCATTCACTGGAATTTTGCGGTTCAGTCGATCAAAGGCTGTCAGTCAGGAGGCGGTCCGGCTTCATTTTTGCTGAAAAT
CCGAAAAGCCGGTCTTGGTTTTATAGAGAAACATGTGCCTGAAACATCTGCGGGTATTGTACAGGCGCTGGTTTTCGGCG
ACAGGTTTCTGATTGAGCAGGACGTGCTGGACGGATATCAAAGCCTCGGGATCATCCATCTTCTAGCCATTTCAGGTCTC
CATGTAGGCATACTTTCGGCCGTTTTATTTTACATGCTGCTCCGGATCGGGATAACGAGGGAACATGCAAAATGGTGCTT
GATCATGATGCTTCCAGCCGCGGTTATGCTGACAGGCGCAGCTCCCTCGGTGCTTAGAGCGGCGTTCATGTCTGAAATAT
ATTTGCTTTCTTCATTGTTCAAGAATCGTTTAAGAGGCGCGCAGGTTCTCAGCATTGCCTGGCTCGGTCTATTGTTATTC
AACCCCTATATGCTTTTCCAGGCAGGTTTTCAGCTTTCTTTTGCAGCATCCTTCGTGTTTATTCTTTCAAAAGAAATACT
TTTAAAACCTAAACATCAAACCGTCAGGCTGCTGTTGGCTTCTTTTGTGGCCCAGCTCGGTTCACTTCCGATTCTTCTCT
TTCACTTTCAAGAGGTTTCCTTCCTCAGTGTCCTCATGAATCTATGTTTTGTACCGTTTTATGTGTTCATCGTGATGCCG
CTGTCATTTGGCGGGTTATTGATTTTGTTGGTTGCGCCTCCTCTTGGGAATCTTGCAATGGGCGTGCTTGACTGGCTGCT
CGGATGGAGCCATTGGGCGGTAAAAGCGGCGTCTTCCCTTGAGATCTTCACGTTCTCCGCTGTTAAACCCGATGTCATCC
ATTTGCTTTTTTATATAGCTTCAATATGTGTCCTTCTGATGTCTATCGAAAAAGCAATCTCTTGCAAAACGCTCGCCATT
CCGGCTTGTCTGCTTGCTTCCGCTTTTCTGTTTCACGCCGCTGCCCCGCATTTCATCGGTTCAGGAGAAGTGACAATGCT
TGATGTCGGGCAGGGAGACAGCATATATATCAGCGCTCCGGGGCAAAAGGGAAATGTTTTAATTGATACCGGAGGGATTG
TTTCCTTTAAAAAGGAGGCATGGCGGGAAAGAAAAAAAGATGTATCCTTGGGAGAAAGAGTATTAATCCCCTTTCTTGCT
TCAAAAGGCGTTAAACAACTTGATGCTTTGATTTTGACGCATGCCGATCATGATCATATGGGAGAGGCTGAAATTCTGAT
CGGGAAAAATAAGGTGAAACAATTGATTGTGCCGAAAGGATATGCGGCAGAACCGGCAGATGAAAAGCTCCTCCGTTTTG
CTCTGGAAAGGGGAGTGGATGTGAAAACGGCAAAGAGAGGGGACCGCTTGGTCATTGGTGATCTGGTGTTTTATGTTCTT
TCGCCGGAAACGGCAGACAAAAACAGCAAAAACAACAGTTCCCTCGTTTTATGGATGAACGCTGGAGGCTTCAGCTGGCT
TTTAACAGGCGATTTGGAAAAGGAAGGCGAGCGGGAGATGCTCAAAGCCTATCCAAGGCTGAAAGCCGACATTCTTAAAG
TCGGCCACCATGGGAGCAAAGGATCGACAGGAGAGGAGCTGATCAACCGTATCGAACCGAAAGCGGCCCTCATATCGGCG
GGGGAAAACAATCGCTACCGCCATCCCCACAAAGAGGTGCTGGAGATTTTAAAACGCCATCAGGTCAAGGTGTTCAGGAC
AGACCGGGACGGAGCGGTTCAGTACCTATTTGGAAGAGGGGACGGAACGTTTTTGCTCCATCCTCCATATGATAAAGTAT
ATTCCCCGTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (508-721)

• Competence protein (Competence) (210-470)

• Domain of unknown function (DUF4131) (DUF4131) (28-171)

3D structure

• AlphaFold DB: M5P6B2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	49.347	98.711	0.487