Detailed information NTG0605376

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: K9N54_RS13790
• Genome accession: NZ_CP083361
• Coordinates: 2875151..2876020 (+)
• Length: 289 a.a.
• NCBI ID: WP_005493974.1
• Uniprot ID: A0A249W3M2
• Organism: Vibrio parahaemolyticus strain 20-082E4
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2870151..2881020

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K9N54_RS13770 (K9N54_13655)	nadC	2870539..2871426 (+)	888	WP_015297249.1	carboxylating nicotinate-nucleotide diphosphorylase	-
K9N54_RS13775 (K9N54_13660)	pilA	2871689..2872147 (+)	459	WP_025518565.1	pilin	Machinery gene
K9N54_RS13780 (K9N54_13665)	pilB	2872153..2873838 (+)	1686	WP_025792845.1	type IV-A pilus assembly ATPase PilB	Machinery gene
K9N54_RS13785 (K9N54_13670)	pilC	2873863..2875086 (+)	1224	WP_005479682.1	type II secretion system F family protein	Machinery gene
K9N54_RS13790 (K9N54_13675)	pilD	2875151..2876020 (+)	870	WP_005493974.1	A24 family peptidase	Machinery gene
K9N54_RS13795 (K9N54_13680)	coaE	2876021..2876635 (+)	615	WP_005480887.1	dephospho-CoA kinase	-
K9N54_RS13800 (K9N54_13685)	zapD	2876663..2877403 (+)	741	WP_015297254.1	cell division protein ZapD	-
K9N54_RS13805 (K9N54_13690)	yacG	2877472..2877666 (+)	195	WP_005462546.1	DNA gyrase inhibitor YacG	-
K9N54_RS13810 (K9N54_13695)	rplS	2877967..2878320 (-)	354	WP_005462554.1	50S ribosomal protein L19	-
K9N54_RS13815 (K9N54_13700)	trmD	2878362..2879105 (-)	744	WP_005462562.1	tRNA (guanosine(37)-N1)-methyltransferase TrmD	-
K9N54_RS13820 (K9N54_13705)	rimM	2879133..2879681 (-)	549	WP_005462552.1	ribosome maturation factor RimM	-
K9N54_RS13825 (K9N54_13710)	rpsP	2879710..2879958 (-)	249	WP_005379962.1	30S ribosomal protein S16	-

Sequence

Protein

• Length: 289 a.a.
• Molecular weight: 32377.43 Da
• Isoelectric Point: 7.1971

>NTDB_id=605376 K9N54_RS13790 WP_005493974.1 2875151..2876020(+) (pilD) [Vibrio parahaemolyticus strain 20-082E4]
MEVFQYYPWLFVVFASIFGLIVGSFLNVVIYRLPKIMELEWRRECAESFPEYKIKPPQEVLTLSVPRSSCQNCATPIRIR
DNIPVISWLLLKGKCHHCHTAISPRYPLIELLTAACAGFVAYHFGFSYFTVALIFFTFVLIAATFIDLDTMLLPDQLTLP
LTWAGIALALTEISPVSLQDAVIGAIAGYLCLWSVYWGFKLLTGKEGMGYGDFKLLAALGAWLGWQSLPMIILLSSVVGV
IFGLVQLRLQKQGIERAFPFGPYLAIAGWASLIWGDQILSWYFTSILGV

Nucleotide

• Length: 870 bp

>NTDB_id=605376 K9N54_RS13790 WP_005493974.1 2875151..2876020(+) (pilD) [Vibrio parahaemolyticus strain 20-082E4]
ATGGAAGTGTTCCAGTACTACCCTTGGCTATTCGTGGTGTTTGCCAGTATCTTCGGTTTAATTGTGGGTAGTTTTCTTAA
TGTAGTCATTTATCGGCTACCTAAAATCATGGAATTAGAATGGCGCCGTGAATGCGCCGAATCATTCCCTGAATATAAGA
TTAAGCCACCTCAAGAAGTTTTGACATTAAGCGTGCCTCGCTCTTCGTGCCAAAACTGCGCGACGCCAATTCGTATTCGA
GACAATATTCCTGTAATCAGCTGGCTACTGTTAAAAGGAAAATGCCATCATTGTCATACCGCAATTAGTCCTCGATATCC
GCTGATAGAATTACTCACTGCAGCGTGCGCTGGTTTTGTGGCTTATCATTTCGGCTTTAGCTACTTTACGGTTGCGTTAA
TCTTTTTCACATTTGTCTTAATAGCCGCGACTTTTATCGATCTCGATACTATGCTGCTACCGGACCAATTAACATTACCA
TTAACTTGGGCTGGCATTGCGTTAGCATTAACAGAAATAAGCCCTGTTAGTCTACAAGACGCCGTAATTGGTGCGATTGC
CGGTTATTTGTGTCTTTGGTCAGTATATTGGGGTTTCAAACTGCTTACTGGTAAAGAAGGCATGGGTTACGGTGATTTTA
AATTGCTGGCTGCCCTTGGCGCTTGGCTAGGATGGCAATCATTACCAATGATCATCCTACTTTCTTCCGTCGTCGGTGTG
ATATTCGGGCTCGTTCAGTTACGACTACAAAAACAAGGTATAGAGAGAGCTTTCCCTTTCGGCCCATATTTAGCGATTGC
AGGATGGGCAAGCTTAATCTGGGGCGATCAAATTCTAAGTTGGTACTTCACGTCAATTTTAGGAGTGTAA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (135-244)

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

3D structure

• AlphaFold DB: A0A249W3M2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio campbellii strain DS40M4	88.927	100	0.889
pilD	Vibrio cholerae strain A1552	73.611	99.654	0.734
pilD	Acinetobacter baumannii D1279779	52.239	92.734	0.484
pilD	Acinetobacter nosocomialis M2	51.866	92.734	0.481
pilD	Neisseria gonorrhoeae MS11	47.101	95.502	0.45