Detailed information NTG0605311

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: NLY78_RS05435
• Genome accession: NZ_CP100435
• Coordinates: 1094047..1095321 (-)
• Length: 424 a.a.
• NCBI ID: WP_012775180.1
• Uniprot ID: A0A0H3MUX4
• Organism: Streptococcus suis strain DE609B
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1089047..1100321

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NLY78_RS05405 (NLY78_05400)	-	1089159..1089305 (+)	147	WP_012027144.1	SPJ_0845 family protein	-
NLY78_RS05410 (NLY78_05405)	-	1089307..1090212 (+)	906	WP_012027145.1	permease	-
NLY78_RS05415 (NLY78_05410)	-	1090209..1091024 (+)	816	WP_012027146.1	TIGR03943 family putative permease subunit	-
NLY78_RS05420 (NLY78_05415)	zwf	1091103..1092590 (+)	1488	WP_012027147.1	glucose-6-phosphate dehydrogenase	-
NLY78_RS05425 (NLY78_05420)	-	1092790..1093464 (+)	675	WP_012027148.1	DNA alkylation repair protein	-
NLY78_RS05430 (NLY78_05425)	-	1093466..1094023 (+)	558	WP_012027149.1	GNAT family N-acetyltransferase	-
NLY78_RS05435 (NLY78_05430)	pilA	1094047..1095321 (-)	1275	WP_012775180.1	signal recognition particle-docking protein FtsY	Machinery gene
NLY78_RS05440 (NLY78_05435)	-	1095323..1096135 (-)	813	WP_002936036.1	Cof-type HAD-IIB family hydrolase	-
NLY78_RS05445 (NLY78_05440)	-	1096125..1096934 (-)	810	WP_012027151.1	Cof-type HAD-IIB family hydrolase	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 47099.51 Da
• Isoelectric Point: 4.4431

>NTDB_id=605311 NLY78_RS05435 WP_012775180.1 1094047..1095321(-) (pilA) [Streptococcus suis strain DE609B]
MGLFDRLFGQKKQEEQVALVEEVEREQSASSEDTVTTEVESATQEMEKFQSEVAETELTAEQEAQKQRTLDMMAQYYAAK
EAAAARVKEAQEQGFDPAIQTKVKEEPVEEVAPVGQESEQDKYQRTLKKTRTGFGARLNEFFANFRSVDEEFFEELEEML
ILSDVGVQVASTLTEELRYEAKLQNAKKIDELRRVIIEKLVDIYEKDGQFSEQINFQDDLTVMLFVGVNGVGKTTSIGKL
AYKYKQAGKKVMLVAADTFRAGAVAQLVEWGRRVDVPVVTGPEKSDPASVVFDGVKRAVAEGVDILMIDTAGRLQNKENL
MAELEKIGRIIKRTLPDAPHETLLALDASTGQNALSQAKEFAKITPLTGLVLTKLDGTAKGGVVLAIRQELDIPVKLIGF
GEKIDDIGEFKSEEFMRGLLEGLV

Nucleotide

• Length: 1275 bp

>NTDB_id=605311 NLY78_RS05435 WP_012775180.1 1094047..1095321(-) (pilA) [Streptococcus suis strain DE609B]
ATGGGATTATTTGATCGATTATTTGGACAAAAAAAACAAGAGGAGCAAGTCGCTCTTGTTGAAGAAGTGGAAAGGGAGCA
GTCGGCTTCTAGCGAAGATACAGTAACTACTGAAGTTGAGTCAGCTACTCAAGAAATGGAAAAGTTCCAGTCTGAAGTAG
CAGAGACTGAATTGACAGCCGAACAAGAAGCTCAGAAACAACGGACCTTAGACATGATGGCTCAATATTATGCAGCCAAA
GAAGCCGCTGCGGCTCGAGTGAAGGAAGCGCAGGAACAAGGCTTTGACCCTGCTATTCAAACCAAGGTCAAGGAAGAGCC
TGTTGAGGAAGTTGCTCCAGTAGGGCAAGAAAGTGAACAGGACAAGTACCAGCGTACCTTGAAAAAGACGCGTACAGGAT
TTGGGGCAAGGCTCAATGAATTCTTTGCCAATTTCCGTTCGGTTGATGAAGAATTTTTCGAAGAGTTGGAAGAAATGCTG
ATTTTGTCAGACGTAGGTGTGCAAGTTGCTTCTACGCTGACAGAGGAGCTCCGCTATGAAGCCAAGCTACAAAATGCCAA
GAAGATAGATGAACTCCGTCGTGTTATCATCGAAAAATTGGTGGATATTTACGAAAAAGACGGTCAATTCAGTGAGCAAA
TCAATTTCCAAGATGATTTGACAGTCATGCTCTTTGTCGGTGTCAACGGTGTTGGGAAGACGACGTCTATCGGTAAGTTA
GCCTACAAGTACAAGCAAGCTGGCAAGAAGGTCATGTTGGTCGCAGCGGACACCTTCCGTGCGGGTGCGGTAGCCCAGCT
GGTCGAGTGGGGTCGCCGTGTCGATGTGCCAGTAGTCACAGGACCTGAAAAGTCAGACCCAGCTAGTGTGGTTTTTGATG
GGGTAAAACGTGCCGTGGCAGAAGGCGTGGATATTCTCATGATTGATACAGCAGGTCGCTTGCAAAATAAAGAAAACCTC
ATGGCAGAGCTGGAAAAAATCGGTCGCATCATCAAACGGACCCTACCTGATGCACCGCATGAAACCCTCTTAGCACTGGA
TGCCTCCACAGGTCAAAACGCCCTCAGTCAAGCCAAGGAATTTGCAAAAATTACTCCATTGACTGGGCTAGTCTTGACCA
AGCTAGACGGTACAGCCAAGGGTGGTGTCGTTCTTGCCATCCGTCAGGAACTGGATATACCAGTTAAGCTAATTGGTTTC
GGTGAGAAAATCGATGACATCGGTGAATTCAAATCCGAAGAATTCATGCGTGGGCTATTGGAAGGATTGGTATAG

Domains

Predicted by InterProScan.

• SRP54-type protein, GTPase domain (SRP54) (221-420)

• SRP54-type protein, helical bundle domain (SRP54_N) (134-200)

3D structure

• AlphaFold DB: A0A0H3MUX4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	36.322	100	0.373