Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   K3A98_RS03965 Genome accession   NZ_CP083259
Coordinates   812879..813595 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain HL25274     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 807879..818595
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K3A98_RS03945 (K3A98_000782) - 808971..809921 (+) 951 WP_000790314.1 LacI family DNA-binding transcriptional regulator -
  K3A98_RS03950 (K3A98_000783) - 810070..811554 (+) 1485 WP_000141419.1 sucrose-6-phosphate hydrolase -
  K3A98_RS03955 (K3A98_000784) - 811551..812510 (+) 960 WP_001253296.1 carbohydrate kinase family protein -
  K3A98_RS03960 (K3A98_000785) - 812700..812807 (-) 108 WP_031785433.1 hypothetical protein -
  K3A98_RS03965 (K3A98_000786) agrA 812879..813595 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  K3A98_RS03970 (K3A98_000787) agrC 813614..814906 (-) 1293 WP_029657921.1 quorum-sensing sensor histidine kinase AgrC -
  K3A98_RS03975 (K3A98_000788) agrD 814931..815071 (-) 141 WP_001094304.1 cyclic lactone autoinducer peptide AgrD -
  K3A98_RS03980 (K3A98_000789) - 815073..815636 (-) 564 WP_001105715.1 accessory gene regulator AgrB -
  K3A98_RS14470 hld 815926..816006 (+) 81 WP_000046022.1 delta-hemolysin -
  K3A98_RS03990 (K3A98_000791) - 816606..817391 (-) 786 WP_031875097.1 carbon-nitrogen family hydrolase -
  K3A98_RS03995 (K3A98_000792) - 817751..818377 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=605141 K3A98_RS03965 WP_000688492.1 812879..813595(-) (agrA) [Staphylococcus aureus strain HL25274]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=605141 K3A98_RS03965 WP_000688492.1 812879..813595(-) (agrA) [Staphylococcus aureus strain HL25274]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAGGATGATCCAGCAGAATTAAGAACACGTATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCTGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAGTCACACAGACTCATTGCGCATTTAGACAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGCTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATTG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1