Detailed information NTG0604944

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: NLG45_RS10615
• Genome accession: NZ_CP100428
• Coordinates: 2149036..2151141 (-)
• Length: 701 a.a.
• NCBI ID: WP_254414309.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain RMSA24
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2144036..2156141

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NLG45_RS10600 (NLG45_10600)	-	2146558..2146785 (+)	228	WP_000932073.1	FeoA family protein	-
NLG45_RS10605 (NLG45_10605)	feoB	2146797..2148791 (+)	1995	WP_000432899.1	ferrous iron transport protein B	-
NLG45_RS10610 (NLG45_10610)	-	2148804..2148974 (+)	171	WP_000111119.1	FeoB-associated Cys-rich membrane protein	-
NLG45_RS10615 (NLG45_10615)	clpE	2149036..2151141 (-)	2106	WP_254414309.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
NLG45_RS10620 (NLG45_10620)	-	2151550..2152071 (+)	522	WP_000455994.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
NLG45_RS10625 (NLG45_10625)	-	2152236..2153402 (-)	1167	WP_000151982.1	hydroxymethylglutaryl-CoA synthase	-
NLG45_RS10630 (NLG45_10630)	-	2153656..2154936 (+)	1281	WP_001180331.1	hydroxymethylglutaryl-CoA reductase, degradative	-
NLG45_RS10635 (NLG45_10635)	-	2155074..2155505 (-)	432	WP_000455861.1	CHAP domain-containing protein	-
NLG45_RS10640 (NLG45_10640)	-	2155895..2156113 (-)	219	WP_000011687.1	sterile alpha motif-like domain-containing protein	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77858.27 Da
• Isoelectric Point: 4.6498

>NTDB_id=604944 NLG45_RS10615 WP_254414309.1 2149036..2151141(-) (clpE) [Staphylococcus aureus strain RMSA24]
MNNGFFNSDFDSIFRRMMQDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAAQRQQGQQGGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISV
DISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLHITA
AHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK

Nucleotide

• Length: 2106 bp

>NTDB_id=604944 NLG45_RS10615 WP_254414309.1 2149036..2151141(-) (clpE) [Staphylococcus aureus strain RMSA24]
ATGAATAACGGTTTTTTCAATAGTGACTTTGATTCAATTTTTCGAAGAATGATGCAAGATATGCAAGGTTCAAATCAAGT
CGGTAACAAAAAGTACTATATTAATGGTAAAGAAGTTTCACCTGAAGAACTAGCGCAACTCACACAACAAGGTGGCAATC
ACTCTGCTGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACAAAGACAACAAGGGCAACAAGGTGGCAACGGCAATTAT
TTAGAACAAATTGGTCGTAACCTTACGCAAGAAGCACGTGACGGTTTATTAGATCCAGTCATTGGTCGTGATAAAGAAAT
TCAAGAAACTGCTGAAGTCTTAAGTAGACGAACTAAAAACAATCCTATATTAGTTGGAGAAGCTGGTGTTGGTAAAACTG
CGATTGTTGAAGGTTTAGCACAGGCAATCGTTGAAGGAAATGTACCAGCAGCAATCAAAGACAAAGAAATTATTTCTGTA
GATATTTCATCATTAGAAGCTGGAACGCAATATCGTGGTGCTTTTGAAGAAAATATTCAAAAATTAATCGAAGGTGTTAA
ATCTTCACAAAATGCCGTACTATTCTTTGATGAAATCCATCAAATTATCGGTTCAGGTGCCACAGGAAGTGATTCAGGTA
GCAAAGGGTTATCTGATATTTTGAAACCTGCATTAAGTCGTGGTGAGATTTCTATTATTGGTGCAACAACACAAGATGAA
TATCGAAACAATATTCTTAAAGATGCTGCATTAACGCGCAGATTTAATGAAGTACTTGTTAATGAACCAAGTGCTAAAGA
TACTGTGGAAATTTTAAAAGGTATTCGCGAAAAATTCGAAGAACACCATCAAGTAAAATTACCAGATGACGTATTAAAAG
CATGTGTTGACTTATCAATTCAATATATTCCACAACGATTATTACCAGATAAAGCAATCGATGTGTTACATATTACAGCA
GCACATTTATCTGCGCAAAGTCCAGCTGTCGATAAAGTTGAAACTGAAAAACGAATTTCTGAATTAGAAAATGATAAACG
TAAAGCGGTAAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATTAAATCATTACAAGATAAATTAGAAA
ATAGTAATGGTGAACATACTGCTGTTGCTACAGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTT
TCTCAAATGGATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATAGGTCAAGATCA
AGCTGTAGAAATGGTTTCACGTGCAATTCGCCGTAATCGTGCTGGGTTTGATGACGGCAACCGTCCAATTGGCAGTTTCC
TATTTGTTGGCCCTACTGGTGTTGGTAAAACAGAGCTTGCTAAACAATTAGCAATTGATCTATTTGGTAATAAAGATGCA
CTGATTCGACTTGATATGAGTGAATATAGTGACACAACAGCTGTTTCAAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGATGACAATTCAAATACGTTAACTGAAAAAGTACGCCGTAATCCATACTCAGTCATTCTATTTGATGAAATCGAAA
AAGCAAATCCACAAATTTTAACATTGTTATTACAAGTAATGGATGATGGTAATTTGACTGATGGTCAAGGTAATGTCATC
AACTTTAAAAATACAATTATTATTTGTACATCAAATGCTGGCTTTGGCAATGGTAATGACGCTGAAGAAAAAGATATTAT
GCACGAAATGAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGCATCGTTGAATTCTTACATTTAGATAAAG
ATGCATTGCAAGATATCGTCAACTTATTATTAGACGATGTACAAGTTACATTAGACAAAAAAGGTATTACGATGGACGTT
TCTCAAGATGCGAAAGATTGGTTAATTGAAGAAGGCTATGATGAAGAATTAGGTGCACGTCCATTAAGACGTATTGTTGA
ACAGCAAGTACGTGACAAAATTACAGATTATTATCTAGATCATACAGACGTTAAACATGTGGATATAGATGTTGAGGATA
ACGAATTAGTCGTAAAAGGTAAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (264-363)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.678	91.726	0.447
clpE	Streptococcus pneumoniae Rx1	48.136	88.017	0.424
clpE	Streptococcus pneumoniae D39	48.136	88.017	0.424
clpE	Streptococcus pneumoniae R6	48.136	88.017	0.424
clpE	Streptococcus pneumoniae TIGR4	48.136	88.017	0.424
clpC	Lactococcus lactis subsp. cremoris KW2	46.656	89.586	0.418
clpC	Bacillus subtilis subsp. subtilis str. 168	44.41	93.153	0.414
clpC	Streptococcus thermophilus LMD-9	44.234	90.3	0.399
clpC	Streptococcus thermophilus LMG 18311	43.918	90.3	0.397
clpC	Streptococcus pneumoniae TIGR4	44.013	88.16	0.388
clpC	Streptococcus pneumoniae Rx1	44.013	88.16	0.388
clpC	Streptococcus pneumoniae D39	44.013	88.16	0.388
clpC	Streptococcus mutans UA159	43.415	87.732	0.381
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.14	92.582	0.381