Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   NLG45_RS00960 Genome accession   NZ_CP100428
Coordinates   196555..197817 (+) Length   420 a.a.
NCBI ID   WP_254414360.1    Uniprot ID   -
Organism   Staphylococcus aureus strain RMSA24     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 191555..202817
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLG45_RS00925 (NLG45_00925) infC 192083..192610 (+) 528 WP_001791162.1 translation initiation factor IF-3 -
  NLG45_RS00930 (NLG45_00930) rpmI 192639..192839 (+) 201 WP_001125540.1 50S ribosomal protein L35 -
  NLG45_RS00935 (NLG45_00935) rplT 192886..193242 (+) 357 WP_001138360.1 50S ribosomal protein L20 -
  NLG45_RS00940 (NLG45_00940) - 193384..193992 (+) 609 WP_000032657.1 NUDIX domain-containing protein -
  NLG45_RS00945 (NLG45_00945) - 194011..194940 (+) 930 WP_001280020.1 hypothetical protein -
  NLG45_RS00950 (NLG45_00950) - 194945..195055 (+) 111 WP_001790560.1 hypothetical protein -
  NLG45_RS00955 (NLG45_00955) tig 195103..196404 (+) 1302 WP_000127574.1 trigger factor -
  NLG45_RS00960 (NLG45_00960) clpX 196555..197817 (+) 1263 WP_254414360.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  NLG45_RS00965 (NLG45_00965) yihA 197971..198561 (+) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  NLG45_RS00970 (NLG45_00970) hemA 198778..200124 (+) 1347 WP_000545452.1 glutamyl-tRNA reductase -
  NLG45_RS00975 (NLG45_00975) ccsA 200146..200961 (+) 816 WP_001157329.1 cytochrome c biogenesis protein -
  NLG45_RS00980 (NLG45_00980) hemC 201003..201929 (+) 927 WP_001230226.1 hydroxymethylbilane synthase -
  NLG45_RS00985 (NLG45_00985) - 201951..202619 (+) 669 WP_154287132.1 uroporphyrinogen-III synthase -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46231.40 Da        Isoelectric Point: 4.2645

>NTDB_id=604877 NLG45_RS00960 WP_254414360.1 196555..197817(+) (clpX) [Staphylococcus aureus strain RMSA24]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADVDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=604877 NLG45_RS00960 WP_254414360.1 196555..197817(+) (clpX) [Staphylococcus aureus strain RMSA24]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATTACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTAGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCATTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACGTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACGACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGCAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531