Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   K8Z23_RS20425 Genome accession   NZ_CP083129
Coordinates   3966405..3967088 (-) Length   227 a.a.
NCBI ID   WP_000350716.1    Uniprot ID   A0A9W5VN71
Organism   Bacillus thuringiensis strain NB-176     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3961405..3972088
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K8Z23_RS20405 (K8Z23_20375) - 3961797..3962135 (-) 339 Protein_4061 competence protein -
  K8Z23_RS20410 (K8Z23_20380) - 3962262..3963698 (-) 1437 WP_001053969.1 IS4-like element IS231C family transposase -
  K8Z23_RS20415 (K8Z23_20385) - 3963790..3964707 (-) 918 Protein_4063 competence protein CoiA -
  K8Z23_RS20420 (K8Z23_20390) - 3964788..3966332 (-) 1545 WP_000799189.1 cardiolipin synthase -
  K8Z23_RS20425 (K8Z23_20395) mecA 3966405..3967088 (-) 684 WP_000350716.1 adaptor protein MecA Regulator
  K8Z23_RS20430 (K8Z23_20400) - 3967434..3968108 (+) 675 WP_000362600.1 TerC family protein -
  K8Z23_RS20435 (K8Z23_20405) spx 3968158..3968553 (-) 396 WP_000258267.1 transcriptional regulator Spx -
  K8Z23_RS20440 (K8Z23_20410) - 3969145..3969348 (+) 204 WP_000559983.1 hypothetical protein -
  K8Z23_RS20445 (K8Z23_20415) - 3969376..3971022 (-) 1647 WP_000727253.1 peptide ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 27009.07 Da        Isoelectric Point: 3.9986

>NTDB_id=604742 K8Z23_RS20425 WP_000350716.1 3966405..3967088(-) (mecA) [Bacillus thuringiensis strain NB-176]
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAEL
SKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQTGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELY
SFENRYYVYVEFDEVLHDEEEIDRILSIILEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT

Nucleotide


Download         Length: 684 bp        

>NTDB_id=604742 K8Z23_RS20425 WP_000350716.1 3966405..3967088(-) (mecA) [Bacillus thuringiensis strain NB-176]
TTGGATATTGAAAGAATTAATGATCATACGATGAAATTTTTTATTACGTACATTGATATAGAGGATAGAGGATTTAATCG
TGAAGAAATTTGGTATGATCGCGAACGAAGTGAAGAGCTCTTTTGGGAGATGATGGACGAAGCTCGTGATCATGACGATT
TCTTTATTGATGGGCCGTTATGGATTCAAGTGCAAGCAGTCGATAAAGGGATTGAAGTACTTGTCACGAAAGCAGAGCTT
TCAAAGGACGGACAAAAGCTGGAACTACCGATAGGGGTAGACAAAATTATAGATATTCCTCTAGATGAAGGCATCGAATC
ATTATTCCAACAAGAGTTAGTCGAAGAGGTAGAAGAACAAACAGGAACAAACTTTAATGAAGATGGTACGTTTGGCTTTT
TAATTAAATTTAATGATTTTGAAGATGTCATTTCATTAAGTCATCGTCTTATCTTTGAAGATATAAAAGATGAGCTGTAT
TCATTTGAGAACCGCTATTATGTATATGTGGAATTCGATGAAGTGCTACATGATGAAGAAGAAATCGATCGTATTTTAAG
TATTATTTTAGAATATGGGGAAGAATCAACTTTAACAATTCATCGTGTAAGTGAGTATGGAAAACAAATTGTGAAAGAGC
ATGCGCTTGAAACGATTCGCAATAATTTTCCTGCTAAAACGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

56.14

100

0.564